How Gender Reassignment Surgery Works (Infographic)

Infographics: How surgery can change the sex of an individual.

Bradley Manning, the U.S. Army private who was sentenced Aug. 21 to 35 years in a military prison for releasing highly sensitive U.S. military secrets, is seeking gender reassignment. Here’s how gender reassignment works:

Converting male anatomy to female anatomy requires removing the penis, reshaping genital tissue to appear more female and constructing a vagina.

An incision is made into the scrotum, and the flap of skin is pulled back. The testes are removed.

A shorter urethra is cut. The penis is removed, and the excess skin is used to create the labia and vagina.

People who have male-to-female gender-reassignment surgery retain a prostate. Following surgery, estrogen (a female hormone) will stimulate breast development, widen the hips, inhibit the growth of facial hair and slightly increase voice pitch.

Female-to-male surgery has achieved lesser success due to the difficulty of creating a functioning penis from the much smaller clitoral tissue available in the female genitals.

The uterus and the ovaries are removed. Genital reconstructive procedures (GRT) use either the clitoris, which is enlarged by hormones, or rely on free tissue grafts from the arm, the thigh or belly and an erectile prosthetic (phalloplasty).

Breasts need to be surgically altered if they are to look less feminine. This process involves removing breast tissue and excess skin, and reducing and properly positioning the nipples and areolae. Androgens (male hormones) will stimulate the development of facial and chest hair, and cause the voice to deepen.

Reliable statistics are extremely difficult to obtain. Many sexual-reassignment procedures are conducted in private facilities that are not subject to reporting requirements.

The cost for female-to-male reassignment can be more than $50,000. The cost for male-to-female reassignment can be $7,000 to $24,000.

Between 100 to 500 gender-reassignment procedures are conducted in the United States each year.

Sign up for the Live Science daily newsletter now

Get the world’s most fascinating discoveries delivered straight to your inbox.

Ross Toro

Man's years of premature ejaculation had a rare cause

Viagra alternatives? Study of mouse erections hints at new ways to treat erectile dysfunction

Gargantuan sunspot 15-Earths wide shoots powerful X-class flare toward Earth, triggering radio blackouts

Most Popular

  • 2 Epic NASA video takes you to the heart of a black hole — and destroys you in seconds
  • 3 2,500-year-old Illyrian helmet found in burial mound likely caused 'awe in the enemy'
  • 4 Record-shattering Tonga volcanic eruption wasn't triggered by what we thought, new study suggests
  • 5 Antarctic ice hole the size of Switzerland keeps cracking open. Now scientists finally know why.
  • 2 Hoard of 17th-century coins hidden during English Civil War unearthed during kitchen renovation
  • 4 Siberia's 'gateway to the underworld' is growing a staggering amount each year
  • 5 EV batteries could last much longer thanks to new capacitor with 19-times higher energy density that scientists created by mistake

how do they do gender reassignment surgery male to female

  • Quick Links
  • Make An Appointment
  • Our Services
  • Price Estimate
  • Price Transparency
  • Pay Your Bill
  • Patient Experience
  • Careers at UH

Schedule an appointment today

University Hospitals Logo

Vaginoplasty: Male to Female (MTF) Genital Reconstructive Surgery

What is vaginoplasty.

Vaginoplasty is a surgical procedure during which surgeons remove the penis and testicles and create a functional vagina. This achieves resolution of gender dysphoria and allows for sexual activity with compatible genitalia. The highly sensitive skin and tissues from the penis are preserved and used to construct the vaginal lining and build a clitoris, resulting in genitals with appropriate sensations. Scrotal skin is used to increase the depth of the vaginal canal. Penile, scrotal and groin skin are refashioned to make the labia majora and minora, and the urethral opening is relocated to an appropriate female position. The final result is an anatomically congruent, aesthetically appealing, and functionally intact vagina. Unless there is a medical reason to do so, the prostate gland is not removed.

University Hospitals has the only reconstructive urology program in the region offering MTF vaginoplasty and other genital gender affirmation surgical procedures. Call 216-844-3009 to schedule a consultation.

Penile Inversion Technique for Vaginoplasty

Penile inversion is the most common type of vaginoplasty and is considered the gold standard for male to female genital reconstruction. This type of gender affirmation surgery can last from two to five hours and is performed with the patient under general anesthesia.

The skin is removed from the penis and inverted to form a pouch which is then inserted into the vaginal cavity created between the urethra and rectum. The urethra is partially removed, shortened and repositioned. Labia majora and labia minora (outer and inner lips), and a clitoris are created. After everything has been sutured in place, a catheter is inserted into the urethra and the area is bandaged. The bandages and catheter will typically remain in place for four to five days. For some patients, a shallow depth vaginoplasty is recommended. This allows for a functional vagina but removes the need for vaginal dilation and douching.

Outcomes after vaginoplasty are excellent, and patients can expect to have aesthetic outcomes and sexual functionality similar to that for cis-women (people that were assigned female sex characteristics at birth and identify as female).

Complications after vaginoplasty are rare, but patients are advised to talk to their doctor about postsurgical risks and how to best manage them.

Things to Consider Before Having a Penile Inversion Vaginoplasty

  • Given that the skin used to construct the new vaginal lining may have abundant hair follicles, patients are recommended to undergo hair removal (either electrolysis or laser hair removal) prior to the vaginoplasty procedure to eliminate the potential for vaginal hair growth. A full course of hair removal can take several months.
  • Patients with fertility concerns should talk to their doctor about ways to save and preserve their sperm before having a vaginoplasty.
  • It is always recommended that patients talk with a therapist in the months leading up to surgery to ensure they are mentally prepared for the transition.
  • In accordance with the World Professional Association of Transgender Health (WPATH) standards of care, patients are required be on appropriate cross-gender hormone therapy for a year, live in the gender-congruent role for a year, and have 2 mental health letters endorsing their suitability for surgery.

Postoperative Care of Your New Vagina

To ensure that your newly constructed vagina maintains the desired depth and width, your UH surgeon  will give you a vaginal dilator to begin using as soon as the bandages are removed. Use the dilator regularly according to your surgeon’s recommendations. This will usually involve inserting the device for ten minutes several times per day for the first three months. After that, once per day for three months followed by two to three times a week until a full year has passed.

Furthermore, regular douching and cleaning of the vagina is recommended. Your surgeon will give you general guidelines for this as well. Approximately 1 out of 10 people who have a vaginoplasty end up requiring a second, minor surgery to correct some of the scarring from the first surgery and improve the function and cosmetic appearance.

Most genital gender affirmation surgeries are covered by insurance. In cases where they are not, your surgeon’s office will guide you through the self-pay options.

  • Patient Care & Health Information
  • Tests & Procedures
  • Feminizing surgery

Feminizing surgery, also called gender-affirming surgery or gender-confirmation surgery, involves procedures that help better align the body with a person's gender identity. Feminizing surgery includes several options, such as top surgery to increase the size of the breasts. That procedure also is called breast augmentation. Bottom surgery can involve removal of the testicles, or removal of the testicles and penis and the creation of a vagina, labia and clitoris. Facial procedures or body-contouring procedures can be used as well.

Not everybody chooses to have feminizing surgery. These surgeries can be expensive, carry risks and complications, and involve follow-up medical care and procedures. Certain surgeries change fertility and sexual sensations. They also may change how you feel about your body.

Your health care team can talk with you about your options and help you weigh the risks and benefits.

Products & Services

  • A Book: Mayo Clinic Family Health Book, 5th Edition
  • Available Sexual Health Solutions at Mayo Clinic Store
  • Newsletter: Mayo Clinic Health Letter — Digital Edition

Why it's done

Many people seek feminizing surgery as a step in the process of treating discomfort or distress because their gender identity differs from their sex assigned at birth. The medical term for this is gender dysphoria.

For some people, having feminizing surgery feels like a natural step. It's important to their sense of self. Others choose not to have surgery. All people relate to their bodies differently and should make individual choices that best suit their needs.

Feminizing surgery may include:

  • Removal of the testicles alone. This is called orchiectomy.
  • Removal of the penis, called penectomy.
  • Removal of the testicles.
  • Creation of a vagina, called vaginoplasty.
  • Creation of a clitoris, called clitoroplasty.
  • Creation of labia, called labioplasty.
  • Breast surgery. Surgery to increase breast size is called top surgery or breast augmentation. It can be done through implants, the placement of tissue expanders under breast tissue, or the transplantation of fat from other parts of the body into the breast.
  • Plastic surgery on the face. This is called facial feminization surgery. It involves plastic surgery techniques in which the jaw, chin, cheeks, forehead, nose, and areas surrounding the eyes, ears or lips are changed to create a more feminine appearance.
  • Tummy tuck, called abdominoplasty.
  • Buttock lift, called gluteal augmentation.
  • Liposuction, a surgical procedure that uses a suction technique to remove fat from specific areas of the body.
  • Voice feminizing therapy and surgery. These are techniques used to raise voice pitch.
  • Tracheal shave. This surgery reduces the thyroid cartilage, also called the Adam's apple.
  • Scalp hair transplant. This procedure removes hair follicles from the back and side of the head and transplants them to balding areas.
  • Hair removal. A laser can be used to remove unwanted hair. Another option is electrolysis, a procedure that involves inserting a tiny needle into each hair follicle. The needle emits a pulse of electric current that damages and eventually destroys the follicle.

Your health care provider might advise against these surgeries if you have:

  • Significant medical conditions that haven't been addressed.
  • Behavioral health conditions that haven't been addressed.
  • Any condition that limits your ability to give your informed consent.

Like any other type of major surgery, many types of feminizing surgery pose a risk of bleeding, infection and a reaction to anesthesia. Other complications might include:

  • Delayed wound healing
  • Fluid buildup beneath the skin, called seroma
  • Bruising, also called hematoma
  • Changes in skin sensation such as pain that doesn't go away, tingling, reduced sensation or numbness
  • Damaged or dead body tissue — a condition known as tissue necrosis — such as in the vagina or labia
  • A blood clot in a deep vein, called deep vein thrombosis, or a blood clot in the lung, called pulmonary embolism
  • Development of an irregular connection between two body parts, called a fistula, such as between the bladder or bowel into the vagina
  • Urinary problems, such as incontinence
  • Pelvic floor problems
  • Permanent scarring
  • Loss of sexual pleasure or function
  • Worsening of a behavioral health problem

Certain types of feminizing surgery may limit or end fertility. If you want to have biological children and you're having surgery that involves your reproductive organs, talk to your health care provider before surgery. You may be able to freeze sperm with a technique called sperm cryopreservation.

How you prepare

Before surgery, you meet with your surgeon. Work with a surgeon who is board certified and experienced in the procedures you want. Your surgeon talks with you about your options and the potential results. The surgeon also may provide information on details such as the type of anesthesia that will be used during surgery and the kind of follow-up care that you may need.

Follow your health care team's directions on preparing for your procedures. This may include guidelines on eating and drinking. You may need to make changes in the medicine you take and stop using nicotine, including vaping, smoking and chewing tobacco.

Because feminizing surgery might cause physical changes that cannot be reversed, you must give informed consent after thoroughly discussing:

  • Risks and benefits
  • Alternatives to surgery
  • Expectations and goals
  • Social and legal implications
  • Potential complications
  • Impact on sexual function and fertility

Evaluation for surgery

Before surgery, a health care provider evaluates your health to address any medical conditions that might prevent you from having surgery or that could affect the procedure. This evaluation may be done by a provider with expertise in transgender medicine. The evaluation might include:

  • A review of your personal and family medical history
  • A physical exam
  • A review of your vaccinations
  • Screening tests for some conditions and diseases
  • Identification and management, if needed, of tobacco use, drug use, alcohol use disorder, HIV or other sexually transmitted infections
  • Discussion about birth control, fertility and sexual function

You also may have a behavioral health evaluation by a health care provider with expertise in transgender health. That evaluation might assess:

  • Gender identity
  • Gender dysphoria
  • Mental health concerns
  • Sexual health concerns
  • The impact of gender identity at work, at school, at home and in social settings
  • The role of social transitioning and hormone therapy before surgery
  • Risky behaviors, such as substance use or use of unapproved hormone therapy or supplements
  • Support from family, friends and caregivers
  • Your goals and expectations of treatment
  • Care planning and follow-up after surgery

Other considerations

Health insurance coverage for feminizing surgery varies widely. Before you have surgery, check with your insurance provider to see what will be covered.

Before surgery, you might consider talking to others who have had feminizing surgery. If you don't know someone, ask your health care provider about support groups in your area or online resources you can trust. People who have gone through the process may be able to help you set your expectations and offer a point of comparison for your own goals of the surgery.

What you can expect

Facial feminization surgery.

Facial feminization surgery may involve a range of procedures to change facial features, including:

  • Moving the hairline to create a smaller forehead
  • Enlarging the lips and cheekbones with implants
  • Reshaping the jaw and chin
  • Undergoing skin-tightening surgery after bone reduction

These surgeries are typically done on an outpatient basis, requiring no hospital stay. Recovery time for most of them is several weeks. Recovering from jaw procedures takes longer.

Tracheal shave

A tracheal shave minimizes the thyroid cartilage, also called the Adam's apple. During this procedure, a small cut is made under the chin, in the shadow of the neck or in a skin fold to conceal the scar. The surgeon then reduces and reshapes the cartilage. This is typically an outpatient procedure, requiring no hospital stay.

Top surgery

Breast incisions for breast augmentation

  • Breast augmentation incisions

As part of top surgery, the surgeon makes cuts around the areola, near the armpit or in the crease under the breast.

Placement of breast implants or tissue expanders

  • Placement of breast implants or tissue expanders

During top surgery, the surgeon places the implants under the breast tissue. If feminizing hormones haven't made the breasts large enough, an initial surgery might be needed to have devices called tissue expanders placed in front of the chest muscles.

Hormone therapy with estrogen stimulates breast growth, but many people aren't satisfied with that growth alone. Top surgery is a surgical procedure to increase breast size that may involve implants, fat grafting or both.

During this surgery, a surgeon makes cuts around the areola, near the armpit or in the crease under the breast. Next, silicone or saline implants are placed under the breast tissue. Another option is to transplant fat, muscles or tissue from other parts of the body into the breasts.

If feminizing hormones haven't made the breasts large enough for top surgery, an initial surgery may be needed to place devices called tissue expanders in front of the chest muscles. After that surgery, visits to a health care provider are needed every few weeks to have a small amount of saline injected into the tissue expanders. This slowly stretches the chest skin and other tissues to make room for the implants. When the skin has been stretched enough, another surgery is done to remove the expanders and place the implants.

Genital surgery

Anatomy before and after penile inversion

  • Anatomy before and after penile inversion

During penile inversion, the surgeon makes a cut in the area between the rectum and the urethra and prostate. This forms a tunnel that becomes the new vagina. The surgeon lines the inside of the tunnel with skin from the scrotum, the penis or both. If there's not enough penile or scrotal skin, the surgeon might take skin from another area of the body and use it for the new vagina as well.

Anatomy before and after bowel flap procedure

  • Anatomy before and after bowel flap procedure

A bowel flap procedure might be done if there's not enough tissue or skin in the penis or scrotum. The surgeon moves a segment of the colon or small bowel to form a new vagina. That segment is called a bowel flap or conduit. The surgeon reconnects the remaining parts of the colon.

Orchiectomy

Orchiectomy is a surgery to remove the testicles. Because testicles produce sperm and the hormone testosterone, an orchiectomy might eliminate the need to use testosterone blockers. It also may lower the amount of estrogen needed to achieve and maintain the appearance you want.

This type of surgery is typically done on an outpatient basis. A local anesthetic may be used, so only the testicular area is numbed. Or the surgery may be done using general anesthesia. This means you are in a sleep-like state during the procedure.

To remove the testicles, a surgeon makes a cut in the scrotum and removes the testicles through the opening. Orchiectomy is typically done as part of the surgery for vaginoplasty. But some people prefer to have it done alone without other genital surgery.

Vaginoplasty

Vaginoplasty is the surgical creation of a vagina. During vaginoplasty, skin from the shaft of the penis and the scrotum is used to create a vaginal canal. This surgical approach is called penile inversion. In some techniques, the skin also is used to create the labia. That procedure is called labiaplasty. To surgically create a clitoris, the tip of the penis and the nerves that supply it are used. This procedure is called a clitoroplasty. In some cases, skin can be taken from another area of the body or tissue from the colon may be used to create the vagina. This approach is called a bowel flap procedure. During vaginoplasty, the testicles are removed if that has not been done previously.

Some surgeons use a technique that requires laser hair removal in the area of the penis and scrotum to provide hair-free tissue for the procedure. That process can take several months. Other techniques don't require hair removal prior to surgery because the hair follicles are destroyed during the procedure.

After vaginoplasty, a tube called a catheter is placed in the urethra to collect urine for several days. You need to be closely watched for about a week after surgery. Recovery can take up to two months. Your health care provider gives you instructions about when you may begin sexual activity with your new vagina.

After surgery, you're given a set of vaginal dilators of increasing sizes. You insert the dilators in your vagina to maintain, lengthen and stretch it. Follow your health care provider's directions on how often to use the dilators. To keep the vagina open, dilation needs to continue long term.

Because the prostate gland isn't removed during surgery, you need to follow age-appropriate recommendations for prostate cancer screening. Following surgery, it is possible to develop urinary symptoms from enlargement of the prostate.

Dilation after gender-affirming surgery

This material is for your education and information only. This content does not replace medical advice, diagnosis and treatment. If you have questions about a medical condition, always talk with your health care provider.

Narrator: Vaginal dilation is important to your recovery and ongoing care. You have to dilate to maintain the size and shape of your vaginal canal and to keep it open.

Jessi: I think for many trans women, including myself, but especially myself, I looked forward to one day having surgery for a long time. So that meant looking up on the internet what the routines would be, what the surgery entailed. So I knew going into it that dilation was going to be a very big part of my routine post-op, but just going forward, permanently.

Narrator: Vaginal dilation is part of your self-care. You will need to do vaginal dilation for the rest of your life.

Alissa (nurse): If you do not do dilation, your vagina may shrink or close. If that happens, these changes might not be able to be reversed.

Narrator: For the first year after surgery, you will dilate many times a day. After the first year, you may only need to dilate once a week. Most people dilate for the rest of their life.

Jessi: The dilation became easier mostly because I healed the scars, the stitches held up a little bit better, and I knew how to do it better. Each transgender woman's vagina is going to be a little bit different based on anatomy, and I grew to learn mine. I understand, you know, what position I needed to put the dilator in, how much force I needed to use, and once I learned how far I needed to put it in and I didn't force it and I didn't worry so much on oh, did I put it in too far, am I not putting it in far enough, and I have all these worries and then I stress out and then my body tenses up. Once I stopped having those thoughts, I relaxed more and it was a lot easier.

Narrator: You will have dilators of different sizes. Your health care provider will determine which sizes are best for you. Dilation will most likely be painful at first. It's important to dilate even if you have pain.

Alissa (nurse): Learning how to relax the muscles and breathe as you dilate will help. If you wish, you can take the pain medication recommended by your health care team before you dilate.

Narrator: Dilation requires time and privacy. Plan ahead so you have a private area at home or at work. Be sure to have your dilators, a mirror, water-based lubricant and towels available. Wash your hands and the dilators with warm soapy water, rinse well and dry on a clean towel. Use a water-based lubricant to moisten the rounded end of the dilators. Water-based lubricants are available over-the-counter. Do not use oil-based lubricants, such as petroleum jelly or baby oil. These can irritate the vagina. Find a comfortable position in bed or elsewhere. Use pillows to support your back and thighs as you lean back to a 45-degree angle. Start your dilation session with the smallest dilator. Hold a mirror in one hand. Use the other hand to find the opening of your vagina. Separate the skin. Relax through your hips, abdomen and pelvic floor. Take slow, deep breaths. Position the rounded end of the dilator with the lubricant at the opening to your vaginal canal. The rounded end should point toward your back. Insert the dilator. Go slowly and gently. Think of its path as a gentle curving swoop. The dilator doesn't go straight in. It follows the natural curve of the vaginal canal. Keep gentle down and inward pressure on the dilator as you insert it. Stop when the dilator's rounded end reaches the end of your vaginal canal. The dilators have dots or markers that measure depth. Hold the dilator in place in your vaginal canal. Use gentle but constant inward pressure for the correct amount of time at the right depth for you. If you're feeling pain, breathe and relax the muscles. When time is up, slowly remove the dilator, then repeat with the other dilators you need to use. Wash the dilators and your hands. If you have increased discharge following dilation, you may want to wear a pad to protect your clothing.

Jessi: I mean, it's such a strange, unfamiliar feeling to dilate and to have a dilator, you know to insert a dilator into your own vagina. Because it's not a pleasurable experience, and it's quite painful at first when you start to dilate. It feels much like a foreign body entering and it doesn't feel familiar and your body kind of wants to get it out of there. It's really tough at the beginning, but if you can get through the first month, couple months, it's going to be a lot easier and it's not going to be so much of an emotional and uncomfortable experience.

Narrator: You need to stay on schedule even when traveling. Bring your dilators with you. If your schedule at work creates challenges, ask your health care team if some of your dilation sessions can be done overnight.

Alissa (nurse): You can't skip days now and do more dilation later. You must do dilation on schedule to keep vaginal depth and width. It is important to dilate even if you have pain. Dilation should cause less pain over time.

Jessi: I hear that from a lot of other women that it's an overwhelming experience. There's lots of emotions that are coming through all at once. But at the end of the day for me, it was a very happy experience. I was glad to have the opportunity because that meant that while I have a vagina now, at the end of the day I had a vagina. Yes, it hurts, and it's not pleasant to dilate, but I have the vagina and it's worth it. It's a long process and it's not going to be easy. But you can do it.

Narrator: If you feel dilation may not be working or you have any questions about dilation, please talk with a member of your health care team.

Research has found that gender-affirming surgery can have a positive impact on well-being and sexual function. It's important to follow your health care provider's advice for long-term care and follow-up after surgery. Continued care after surgery is associated with good outcomes for long-term health.

Before you have surgery, talk to members of your health care team about what to expect after surgery and the ongoing care you may need.

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

Feminizing surgery care at Mayo Clinic

  • Tangpricha V, et al. Transgender women: Evaluation and management. https://www.uptodate.com/ contents/search. Accessed Aug. 16, 2022.
  • Erickson-Schroth L, ed. Surgical transition. In: Trans Bodies, Trans Selves: A Resource by and for Transgender Communities. 2nd ed. Kindle edition. Oxford University Press; 2022. Accessed Aug. 17, 2022.
  • Coleman E, et al. Standards of care for the health of transgender and gender diverse people, version 8. International Journal of Transgender Health. 2022; doi:10.1080/26895269.2022.2100644.
  • AskMayoExpert. Gender-affirming procedures (adult). Mayo Clinic; 2022.
  • Nahabedian, M. Implant-based breast reconstruction and augmentation. https://www.uptodate.com/contents/search. Accessed Aug. 17, 2022.
  • Erickson-Schroth L, ed. Medical transition. In: Trans Bodies, Trans Selves: A Resource by and for Transgender Communities. 2nd ed. Kindle edition. Oxford University Press; 2022. Accessed Aug. 17, 2022.
  • Ferrando C, et al. Gender-affirming surgery: Male to female. https://www.uptodate.com/contents/search. Accessed Aug. 17, 2022.
  • Doctors & Departments
  • Care at Mayo Clinic

Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.

  • Opportunities

Mayo Clinic Press

Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press .

  • Mayo Clinic on Incontinence - Mayo Clinic Press Mayo Clinic on Incontinence
  • The Essential Diabetes Book - Mayo Clinic Press The Essential Diabetes Book
  • Mayo Clinic on Hearing and Balance - Mayo Clinic Press Mayo Clinic on Hearing and Balance
  • FREE Mayo Clinic Diet Assessment - Mayo Clinic Press FREE Mayo Clinic Diet Assessment
  • Mayo Clinic Health Letter - FREE book - Mayo Clinic Press Mayo Clinic Health Letter - FREE book

Your gift holds great power – donate today!

Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine.

  • Reference Manager
  • Simple TEXT file

People also looked at

Original research article, male-to-female gender-affirming surgery: 20-year review of technique and surgical results.

how do they do gender reassignment surgery male to female

  • 1 Serviço de Urologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • 2 Serviço de Psiquiatria, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
  • 3 Serviço de Psiquiatria, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil

Purpose: Gender dysphoria (GD) is an incompatibility between biological sex and personal gender identity; individuals harbor an unalterable conviction that they were born in the wrong body, which causes personal suffering. In this context, surgery is imperative to achieve a successful gender transition and plays a key role in alleviating the associated psychological discomfort. In the current study, a retrospective cohort, we report the 20-years outcomes of the gender-affirming surgery performed at a single Brazilian university center, examining demographic data, intra and postoperative complications. During this period, 214 patients underwent penile inversion vaginoplasty.

Results: Results demonstrate that the average age at the time of surgery was 32.2 years (range, 18–61 years); the average of operative time was 3.3 h (range 2–5 h); the average duration of hormone therapy before surgery was 12 years (range 1–39). The most commons minor postoperative complications were granulation tissue (20.5 percent) and introital stricture of the neovagina (15.4 percent) and the major complications included urethral meatus stenosis (20.5 percent) and hematoma/excessive bleeding (8.9 percent). A total of 36 patients (16.8 percent) underwent some form of reoperation. One hundred eighty-one (85 percent) patients in our series were able to have regular sexual intercourse, and no individual regretted having undergone GAS.

Conclusions: Findings confirm that it is a safety procedure, with a low incidence of serious complications. Otherwise, in our series, there were a high level of functionality of the neovagina, as well as subjective personal satisfaction.

Introduction

Transsexualism (ICD-10) or Gender Dysphoria (GD) (DSM-5) is characterized by intense and persistent cross-gender identification which influences several aspects of behavior ( 1 ). The terms describe a situation where an individual's gender identity differs from external sexual anatomy at birth ( 1 ). Gender identity-affirming care, for those who desire, can include hormone therapy and affirming surgeries, as well as other procedures such as hair removal or speech therapy ( 1 ).

Since 1998, the Gender Identity Program (PROTIG) of the Hospital de Clínicas de Porto Alegre (HCPA), Universidade Federal do Rio Grande do Sul, Brazil has provided public assistance to transsexual people, is the first one in Brazil and one of the pioneers in South America. Our program offers psychosocial support, health care, and guidance to families, and refers individuals for gender-affirming surgery (GAS) when indicated. To be eligible for this surgery, transsexual individuals must have been adherent to multidisciplinary follow-up for at least 2 years, have a minimum age of 21 years (required for surgical procedures of this nature), have a positive psychiatric or psychological report, and have a diagnosis of GD.

Gender-affirming surgery (GAS) is increasingly recognized as a therapeutic intervention and a medical necessity, with growing societal acceptance ( 2 ). At our institution, we perform the classic penile inversion vaginoplasty (PIV), with an inverted penis skin flap used as the lining for the neovagina. Studies have demonstrated that GAS for the management of GD can promote improvements in mental health and social relationships for these patients ( 2 – 5 ). It is therefore imperative to understand and establish best practice techniques for this patient population ( 2 ). Although there are several studies reporting the safety and efficacy of gender-affirming surgery by penile inversion vaginoplasty, we present the largest South-American cohort to date, examining demographic data, intra and postoperative complications.

Patients and Methods

Subjects and study setup.

This is a retrospective cohort study of Brazilian transgender women who underwent penile inversion vaginoplasty between January of 2000 and March of 2020 at the Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil. The study was approved by our institutional medical and research ethics committee.

At our institution, gender-affirming surgery is indicated for transgender women who are under assistance by our program for transsexual individuals. All transsexual women included in this study had at least 2 years of experience as a woman and met WPATH standards for GAS ( 1 ). Patients were submitted to biweekly group meetings and monthly individual therapy.

Between January of 2000 and March of 2020, a total of 214 patients underwent penile inversion vaginoplasty. The surgical procedures were performed by two separate staff members, mostly assisted by residents. A retrospective chart review was conducted recording patient demographics, intraoperative and postoperative complications, reoperations, and secondary surgical procedures. Informed consent was obtained from all individual participants included in the study.

Hormonal Therapy

The goal of feminizing hormone therapy is the development of female secondary sex characteristics, and suppression/minimization of male secondary sex characteristics.

Our general therapy approach is to combine an estrogen with an androgen blocker. The usual estrogen is the oral preparation of estradiol (17-beta estradiol), starting at a dose of 2 mg/day until the maximum dosage of 8 mg/day. The preferred androgen blocker is spironolactone at a dose of 200 mg twice a day.

Operative Technique

At our institution, we perform the classic penile inversion vaginoplasty, with an inverted penis skin flap used as the lining for the neovagina. For more details, we have previously published our technique with a step-by-step procedure video ( 6 ). All individuals underwent intestinal cleansing the evening before the surgery. A first-generation cephalosporin was used as preoperative prophylaxis. The procedure was performed with the patient in a dorsal lithotomy position. A Foley catheter was placed for bladder catheterization. A inverted-V incision was made 4 cm above the anus and a flap was created. A neovaginal cavity was created between the prostate and the rectum with blunt dissection, in the Denonvilliers space, until the peritoneal fold, usually measuring 12 cm in extension and 6 cm in width. The incision was then extended vertically to expose the testicles and the spermatic cords, which were removed at the level of the external inguinal rings. A circumferential subcoronal incision was made ( Figure 1 ), the penis was de-gloved and a skin flap was created, with the de-gloved penis being passed through the scrotal opening ( Figure 2 ). The dorsal part of the glans and its neurovascular bundle were bluntly dissected away from the penile shaft ( Figure 3 ) as well as the urethra, which included a portion of the bulbospongious muscle ( Figure 4 ). The corpora cavernosa was excised up to their attachments at the symphysis pubis and ligated. The neoclitoris was shaped and positioned in the midline at the level of the symphysis pubis and sutured using interrupted 5-0 absorbable suture. The corpus spongiosum was reduced and the urethra was shortened, spatulated, and placed 1 cm below the neoclitoris in the midline and sutured using interrupted 4-0 absorbable suture. The penile skin flap was inverted and pulled into the neovaginal cavity to become its walls ( Figure 5 ). The excess of skin was then removed, and the subcutaneous tissue and the skin were closed using continuous 3-0 non-absorbable suture ( Figure 6 ). A neo mons pubis was created using a 0 absorbable suture between the skin and the pubic bone. The skin flap was fixed to the pubic bone using a 0 absorbable suture. A gauze impregnated with Vaseline and antibiotic ointment was left inside the neovagina, and a customized compressive bandage was applied ( Figure 7 —shows the final appearance after the completion of the procedures).

www.frontiersin.org

Figure 1 . The initial circumferential subcoronal incision.

www.frontiersin.org

Figure 2 . The de-gloved penis being passed through the scrotal opening.

www.frontiersin.org

Figure 3 . The dorsal part of the glans and its neurovascular bundle dissected away from the penile shaft.

www.frontiersin.org

Figure 4 . The urethra dissected including a portion of the bulbospongious muscle. The grey arrow shows the penile shaft and the white arrow shows the dissected urethra.

www.frontiersin.org

Figure 5 . The inverted penile skin flap.

www.frontiersin.org

Figure 6 . The neoclitoris and the urethra sutured in the midline and the neovaginal cavity.

www.frontiersin.org

Figure 7 . The final appearance after the completion of the procedures.

Postoperative Care and Follow-Up

The patients were usually discharged within 2 days after surgery with the Foley catheter and vaginal gauze packing in place, which were removed after 7 days in an ambulatorial attendance.

Our vaginal dilation protocol starts seven days after surgery: a kit of 6 silicone dilators with progressive diameter (1.1–4 cm) and length (6.5–14.5 cm) is used; dilation is done progressively from the smallest dilator; each size should be kept in place for 5 min until the largest possible size, which is kept for 3 h during the day and during the night (sleep), if possible. The process is performed daily for the first 3 months and continued until the patient has regular sexual intercourse.

The follow-up visits were performed 7 days, 1, 2, 3, 6, and 12 months after surgery ( Figure 8 ), and included physical examination and a quality-of-life questionnaire.

www.frontiersin.org

Figure 8 . Appearance after 1 month of the procedure.

Statistical Analysis

The statistical analysis was conducted using Statistical Product and Service Solutions Version 18.0 (SPSS). Outcome measures were intra-operative and postoperative complications, re-operations. Descriptive statistics were used to evaluate the study outcomes. Mean values and standard deviations or median values and ranges are presented as continuous variables. Frequencies and percentages are reported for dichotomous and ordinal variables.

Patient Demographics

During the period of the study, 214 patients underwent penile inversion vaginoplasty, performed by two staff surgeons, mostly assisted by residents ( Table 1 ). The average age at the time of surgery was 32.2 years (range 18–61 years). There was no significant increase or decrease in the ages of patients who underwent SRS over the study period (Fisher's exact test: P = 0.065; chi-square test: X 2 = 5.15; GL = 6; P = 0.525). The average of operative time was 3.3 h (range 2–5 h). The average duration of hormone therapy before surgery was 12 years (range 1–39). The majority of patients were white (88.3 percent). The most prevalent patient comorbidities were history of tobacco use (15 percent), human immunodeficiency virus infection (13 percent) and hypertension (10.7 percent). Other comorbidities are listed in Table 1 .

www.frontiersin.org

Table 1 . Patient demographics.

Multidisciplinary follow-up was comprised of 93.45% of patients following up with a urologist and 59.06% of patients continuing psychiatric follow-up, median follow-up time of 16 and 9.3 months after surgery, respectively.

Postoperative Results

The complications were classified according to the Clavien-Dindo score ( Table 2 ). The most common minor postoperative complications (Grade I) were granulation tissue (20.5 percent), introital stricture of the neovagina (15.4 percent) and wound dehiscence (12.6 percent). The major complications (Grade III-IV) included urethral stenosis (20.5 percent), urethral fistula (1.9 percent), intraoperative rectal injury (1.9 percent), necrosis (primarily along the wound edges) (1.4 percent), and rectovaginal fistula (0.9 percent). A total of 17 patients required blood transfusion (7.9 percent).

www.frontiersin.org

Table 2 . Complications after penile inversion vaginoplasty.

A total of 36 patients (16.8 percent) underwent some form of reoperation.

One hundred eighty-one (85 percent) patients in our series were able to have regular sexual vaginal intercourse, and no individual regretted having undergone GAS.

Penile inversion vaginoplasty is the gold-standard in gender-affirming surgery. It has good functional outcomes, and studies have demonstrated adequate vaginal depths ( 3 ). It is recognized not only as a cosmetic procedure, but as a therapeutic intervention and a medical necessity ( 2 ). We present the largest South-American cohort to date, examining demographic data, intra and postoperative complications.

The mean age of transsexual women who underwent GAS in our study was 32.2 years (range 18–61 years), which is lower than the mean age of patients in studies found in the literature. Two studies indicated that the mean ages of patients at time of GAS were 36.7 years and 41 years, respectively ( 4 , 5 ). Another study reported a mean age at time of GAS of 36 years and found there was a significant decrease in age at the time of GAS from 41 years in 1994 to 35 years in 2015 ( 7 ). According to the authors, this decrease in age is associated with greater tolerance and societal approval regarding individuals with GD ( 7 ).

There was no grade IV or grade V complications. Excessive bleeding noticed postoperatively occurred in 19 patients (8.9 percent) and blood transfusion was required in 17 cases (7.9 percent); all patients who required blood transfusions were operated until July 2011, and the reason for this rate of blood transfusion was not identified.

The most common intraoperative complication was rectal injury, occurring in 4 patients (1.9 percent); in all patients the lesion was promptly identified and corrected in 2 layers absorbable sutures. In 2 of these patients, a rectovaginal fistula became evident, requiring fistulectomy and colonic transit deviation. This is consistent with current literature, in which rectal injury is reported in 0.4–4.5 percent of patients ( 4 , 5 , 8 – 13 ). Goddard et al. suggested carefully checking for enterotomy after prostate and bladder mobilization by digital rectal examination ( 4 ). Gaither et al. ( 14 ) commented that careful dissection that closely follows the urethra along its track from the central tendon of the perineum up through the lower pole of the prostate is critical and only blunt dissection is encouraged after Denonvilliers' fascia is reached. Alternatively, a robotic-assisted approach to penile inversion vaginoplasty may aid in minimizing these complications. The proposed advantages of a robotic-assisted vaginoplasty include safer dissection to minimize the risk of rectal injury and better proximal vaginal fixation. Dy et al. ( 15 ) has had no rectal injuries or fistulae to date in his series of 15 patients, with a mean follow-up of 12 months.

In our series, we observed 44 cases (20.5 percent) of urethral meatus strictures. We credit this complication to the technique used in the initial 5 years of our experience, in which the urethra was shortened and sutured in a circular fashion without spatulation. All cases were treated with meatal dilatation and 11 patients required surgical correction, being performed a Y-V plastic reconstruction of the urethral meatus. In the literature, meatal strictures are relatively rare in male-to-female (MtF) GAS due to the spatulation of the urethra and a simple anastomosis to the external genitalia. Recent systematic reviews show an incidence of five percent in this complication ( 16 , 17 ). Other studies report a wide incidence of meatal stenosis ranging from 1.1 to 39.8 percent ( 4 , 8 , 11 ).

Neovagina introital stricture was observed in 33 patients (15.4 percent) in our study and impedes the possibility of neovaginal penetration and/or adversely affects sexual life quality. In the literature, the reported incidence of introital stenosis range from 6.7 to 14.5 percent ( 4 , 5 , 8 , 9 , 11 – 13 ). According to Hadj-Moussa et al. ( 18 ) a regimen of postoperative prophylactic dilation is crucial to minimize the development of this outcome. At our institution, our protocol for vaginal dilation started seven days after surgery and was performed three to four times a day during the first 3 months and was continued until the individual had regular sexual intercourse. We treated stenosis initially with dilation. In case of no response, we propose a surgical revision with diamond-shaped introitoplasty with relaxing incisions. In recalcitrant cases, we proposed to the patient a secondary vaginoplasty using a full-thickness skin graft of the lower abdomen.

One hundred eighty-one (85 percent) patients were classified as having a “functional vagina,” characterized as the capacity to maintain satisfactory sexual vaginal intercourse, since the mean neovaginal depth was not measured. In a review article, the mean neovaginal depth ranged from 10 to 13.5 cm, with the shallowest neovagina depth at 2.5 cm and the deepest at 18 cm ( 17 ). According to Salim et al. ( 19 ), in terms of postoperative functional outcomes after penile inversion vaginoplasty, a mean percentage of 75 percent (range from 33 to 87 percent) patients were having vaginal intercourse. Hess et al. found that 91.4% of patients who responded to a questionnaire were very satisfied (34.4%), satisfied (37.6%), or mostly satisfied (19.4%) with their sexual function after penile inversion vaginoplasty ( 20 ).

Poor cosmetic appearance of the vulva is common. Amend et al. reported that the most common reason for reoperation was cosmetic correction in the form of mons pubis and mucosa reduction in 50% of patients ( 16 ). We had no patient regrets about performing GAS, although 36 patients (16.8 percent) were reoperated due to cosmetic issues. Gaither et al. propose in order to minimize scarring to use a one-stage surgical approach and the lateralization of surgical scars to the groin ( 14 ). Frequently, cosmetic issues outcomes are often patient driven and preoperative patient education is necessary ( 14 ).

Analyzing the quality of life, in 2016, our health care group (PROTIG) published a study assessing quality of life before and after gender-affirming surgery in 47 patients using the diagnostic tool 100-item WHO Quality of Life Assessment (WHOQOL-100) ( 21 ). The authors found that GAS promotes the improvement of psychological aspects and social relations. However, even 1 year after GAS, MtF persons continue to report problems in physical and difficulty in recovering their independence. In a systematic review and meta-analysis of QOL and psychosocial outcomes in transsexual people, researchers verified that sex reassignment with hormonal interventions more likely corrects gender dysphoria, psychological functioning and comorbidities, sexual function, and overall QOL compared with sex reassignment without hormonal interventions, although there is a low level of evidence for this ( 22 ). Recently, Castellano et al. assessed QOL in 60 Italian transsexuals (46 transwomen and 14 transmen) at least 2 years after SRS using the WHOQOL-100 (general QOL score and quality of sexual life and quality of body image scores) to focus on the effects of hormonal therapy. Overall satisfaction improved after SRS, and QOL was similar to the controls ( 23 ). Bartolucci et al. evaluated the perception of quality of sexual life using four questions evaluating the sexual facet in individuals with gender dysphoria before SRS and the possible factors associated with this perception. The study showed that approximately half the subjects with gender dysphoria perceived their sexual life as “poor/dissatisfied” or “very poor/very dissatisfied” before SRS ( 24 ).

Our study has some limitations. The total number of operated patients is restricted within the long follow-up period. This is due to a limitation in our health system, which allows only 1 sexual reassignment surgery to be performed per month at our institution. Neovagin depth measurement was not performed routinely in the follow-up of operated patients.

Conclusions

The definitive treatment for patients with gender dysphoria is gender-affirming surgery. Our series demonstrates that GAS is a feasible surgery with low rates of serious complications. We emphasize the high level of functionality of the vagina after the procedure, as well as subjective personal satisfaction. Complications, especially minor ones, are probably underestimated due to the nature of the study, and since this is a surgical population, the results may not be generalizable for all transgender MTF individuals.

Data Availability Statement

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

Ethics Statement

The studies involving human participants were reviewed and approved by Hospital de Clínicas de Porto Alegre. The patients/participants provided their written informed consent to participate in this study.

Author Contributions

GM: conception and design, data acquisition, data analysis, interpretation, drafting the manuscript, review of the literature, critical revision of the manuscript and factual content, and statistical analysis. ML and TR: conception and design, data interpretation, drafting the manuscript, critical revision of the manuscript and factual content, and statistical analysis. DS, KS, AF, AC, PT, AG, and RC: conception and design, data acquisition and data analysis, interpretation, drafting the manuscript, and review of the literature. All authors contributed to the article and approved the submitted version.

This study was supported by the Fundo de Incentivo à Pesquisa e Eventos (FIPE - Fundo de Incentivo à Pesquisa e Eventos) of Hospital de Clínicas de Porto Alegre.

Conflict of Interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

1. Coleman E, Bockting W, Botzer M, Cohen-Kettenis P, DeCuypere G, Feldman J, et al. Standards of care for the health of transsexual, transgender, and gender-non-conforming people, version 7. Int J Transgend. (2012) 13:165–232. doi: 10.1080/15532739.2011.700873

CrossRef Full Text | Google Scholar

2. Massie JP, Morrison SD, Maasdam JV, Satterwhite T. Predictors of patient satisfaction and postoperative complications in penile inversion vaginoplasty. Plast Reconstruct Surg. (2018) 141:911–921. doi: 10.1097/PRS.0000000000004427

PubMed Abstract | CrossRef Full Text | Google Scholar

3. Pan S, Honig SC. Gender-affirming surgery: current concepts. Curr Urol Rep . (2018) 19:62. doi: 10.1007/s11934-018-0809-9

4. Goddard JC, Vickery RM, Qureshi A, Summerton DJ, Khoosal D, Terry TR. Feminizing genitoplasty in adult transsexuals: early and long-term surgical results. BJU Int . (2007) 100:607–13. doi: 10.1111/j.1464-410X.2007.07017.x

5. Rossi NR, Hintz F, Krege S, Rübben H, Vom DF, Hess J. Gender reassignment surgery – a 13 year review of surgical outcomes. Eur Urol Suppl . (2013) 12:e559. doi: 10.1016/S1569-9056(13)61042-8

6. Silva RUM, Abreu FJS, Silva GMV, Santos JVQV, Batezini NSS, Silva Neto B, et al. Step by step male to female transsexual surgery. Int Braz J Urol. (2018) 44:407–8. doi: 10.1590/s1677-5538.ibju.2017.0044

7. Aydin D, Buk LJ, Partoft S, Bonde C, Thomsen MV, Tos T. Transgender surgery in Denmark from 1994 to 2015: 20-year follow-up study. J Sex Med. (2016) 13:720–5. doi: 10.1016/j.jsxm.2016.01.012

8. Perovic SV, Stanojevic DS, Djordjevic MLJ. Vaginoplasty in male transsexuals using penile skin and a urethral flap. BJU Int. (2001) 86:843–50. doi: 10.1046/j.1464-410x.2000.00934.x

9. Krege S, Bex A, Lümmen G, Rübben H. Male-to-female transsexualism: a technique, results and long-term follow-up in 66 patients. BJU Int. (2001) 88:396–402. doi: 10.1046/j.1464-410X.2001.02323.x

10. Wagner S, Greco F, Hoda MR, Inferrera A, Lupo A, Hamza A, et al. Male-to-female transsexualism: technique, results and 3-year follow-up in 50 patients. Urol International. (2010) 84:330–3. doi: 10.1159/000288238

11. Reed H. Aesthetic and functional male to female genital and perineal surgery: feminizing vaginoplasty. Semin PlasticSurg. (2011) 25:163–74. doi: 10.1055/s-0031-1281486

12. Raigosa M, Avvedimento S, Yoon TS, Cruz-Gimeno J, Rodriguez G, Fontdevila J. Male-to-female genital reassignment surgery: a retrospective review of surgical technique and complications in 60 patients. J Sex Med. (2015) 12:1837–45. doi: 10.1111/jsm.12936

13. Sigurjonsson H, Rinder J, Möllermark C, Farnebo F, Lundgren TK. Male to female gender reassignment surgery: surgical outcomes of consecutive patients during 14 years. JPRAS Open. (2015) 6:69–73. doi: 10.1016/j.jpra.2015.09.003

14. Gaither TW, Awad MA, Osterberg EC, Murphy GP, Romero A, Bowers ML, et al. Postoperative complications following primary penile inversion vaginoplasty among 330 male-to-female transgender patients. J Urol. (2018) 199:760–5. doi: 10.1016/j.juro.2017.10.013

15. Dy GW, Sun J, Granieri MA, Zhao LC. Reconstructive management pearls for the transgender patient. Curr. Urol. Rep. (2018) 19:36. doi: 10.1007/s11934-018-0795-y

16. Amend B, Seibold J, Toomey P, Stenzl A, Sievert KD. Surgical reconstruction for male-to-female sex reassignment. Eur Urol. (2013) 64:141–9. doi: 10.1016/j.eururo.2012.12.030

17. Horbach SER, Bouman MB, Smit JM, Özer M, Buncamper ME, Mullender MG. Outcome of vaginoplasty in male-to-female transgenders: a systematic review of surgical techniques. J Sex Med . (2015) 12:1499–512. doi: 10.1111/jsm.12868

18. Hadj-Moussa M, Ohl DA, Kuzon WM. Feminizing genital gender-confirmation surgery. Sex Med Rev. (2018) 6:457–68.e2. doi: 10.1016/j.sxmr.2017.11.005

19. Salim A, Poh M. Gender-affirming penile inversion vaginoplasty. Clin Plast Surg. (2018) 45:343–50. doi: 10.1016/j.cps.2018.04.001

20. Hess J, Rossi NR, Panic L, Rubben H, Senf W. Satisfaction with male-to-female gender reassignment surgery. DtschArztebl Int. (2014) 111:795–801. doi: 10.3238/arztebl.2014.0795

21. Silva DC, Schwarz K, Fontanari AMV, Costa AB, Massuda R, Henriques AA, et al. WHOQOL-100 before and after sex reassignment surgery in brazilian male-to-female transsexual individuals. J Sex Med. (2016) 13:988–93. doi: 10.1016/j.jsxm.2016.03.370

22. Murad MH, Elamin MB, Garcia MZ, Mullan RJ, Murad A, Erwin PJ, et al. Hormonal therapy and sex reassignment: a systematic review and meta-analysis of quality of life and psychosocial outcomes. Clin Endocrinol . (2010) 72:214–31. doi: 10.1111/j.1365-2265.2009.03625.x

23. Castellano E, Crespi C, Dell'Aquila C, Rosato R, Catalano C, Mineccia V, et al. Quality of life and hormones after sex reassignment surgery. J Endocrinol Invest . (2015) 38:1373–81. doi: 10.1007/s40618-015-0398-0

24. Bartolucci C, Gómez-Gil E, Salamero M, Esteva I, Guillamón A, Zubiaurre L, et al. Sexual quality of life in gender-dysphoric adults before genital sex reassignment surgery. J Sex Med . (2015) 12:180–8. doi: 10.1111/jsm.12758

Keywords: transsexualism, gender dysphoria, gender-affirming genital surgery, penile inversion vaginoplasty, surgical outcome

Citation: Moisés da Silva GV, Lobato MIR, Silva DC, Schwarz K, Fontanari AMV, Costa AB, Tavares PM, Gorgen ARH, Cabral RD and Rosito TE (2021) Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique and Surgical Results. Front. Surg. 8:639430. doi: 10.3389/fsurg.2021.639430

Received: 17 December 2020; Accepted: 22 March 2021; Published: 05 May 2021.

Reviewed by:

Copyright © 2021 Moisés da Silva, Lobato, Silva, Schwarz, Fontanari, Costa, Tavares, Gorgen, Cabral and Rosito. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Gabriel Veber Moisés da Silva, veber.gabriel@gmail.com

This article is part of the Research Topic

Gender Dysphoria: Diagnostic Issues, Clinical Aspects and Health Promotion

  • Search the site GO Please fill out this field.
  • Newsletters
  • Mental Health
  • Social and Public Health

What Is Gender Affirmation Surgery?

how do they do gender reassignment surgery male to female

A gender affirmation surgery allows individuals, such as those who identify as transgender or nonbinary, to change one or more of their sex characteristics. This type of procedure offers a person the opportunity to have features that align with their gender identity.

For example, this type of surgery may be a transgender surgery like a male-to-female or female-to-male surgery. Read on to learn more about what masculinizing, feminizing, and gender-nullification surgeries may involve, including potential risks and complications.

Why Is Gender Affirmation Surgery Performed?

A person may have gender affirmation surgery for different reasons. They may choose to have the surgery so their physical features and functional ability align more closely with their gender identity.

For example, one study found that 48,019 people underwent gender affirmation surgeries between 2016 and 2020. Most procedures were breast- and chest-related, while the remaining procedures concerned genital reconstruction or facial and cosmetic procedures.

In some cases, surgery may be medically necessary to treat dysphoria. Dysphoria refers to the distress that transgender people may experience when their gender identity doesn't match their sex assigned at birth. One study found that people with gender dysphoria who had gender affirmation surgeries experienced:

  • Decreased antidepressant use
  • Decreased anxiety, depression, and suicidal ideation
  • Decreased alcohol and drug abuse

However, these surgeries are only performed if appropriate for a person's case. The appropriateness comes about as a result of consultations with mental health professionals and healthcare providers.

Transgender vs Nonbinary

Transgender and nonbinary people can get gender affirmation surgeries. However, there are some key ways that these gender identities differ.

Transgender is a term that refers to people who have gender identities that aren't the same as their assigned sex at birth. Identifying as nonbinary means that a person doesn't identify only as a man or a woman. A nonbinary individual may consider themselves to be:

  • Both a man and a woman
  • Neither a man nor a woman
  • An identity between or beyond a man or a woman

Hormone Therapy

Gender-affirming hormone therapy uses sex hormones and hormone blockers to help align the person's physical appearance with their gender identity. For example, some people may take masculinizing hormones.

"They start growing hair, their voice deepens, they get more muscle mass," Heidi Wittenberg, MD , medical director of the Gender Institute at Saint Francis Memorial Hospital in San Francisco and director of MoZaic Care Inc., which specializes in gender-related genital, urinary, and pelvic surgeries, told Health .

Types of hormone therapy include:

  • Masculinizing hormone therapy uses testosterone. This helps to suppress the menstrual cycle, grow facial and body hair, increase muscle mass, and promote other male secondary sex characteristics.
  • Feminizing hormone therapy includes estrogens and testosterone blockers. These medications promote breast growth, slow the growth of body and facial hair, increase body fat, shrink the testicles, and decrease erectile function.
  • Non-binary hormone therapy is typically tailored to the individual and may include female or male sex hormones and/or hormone blockers.

It can include oral or topical medications, injections, a patch you wear on your skin, or a drug implant. The therapy is also typically recommended before gender affirmation surgery unless hormone therapy is medically contraindicated or not desired by the individual.

Masculinizing Surgeries

Masculinizing surgeries can include top surgery, bottom surgery, or both. Common trans male surgeries include:

  • Chest masculinization (breast tissue removal and areola and nipple repositioning/reshaping)
  • Hysterectomy (uterus removal)
  • Metoidioplasty (lengthening the clitoris and possibly extending the urethra)
  • Oophorectomy (ovary removal)
  • Phalloplasty (surgery to create a penis)
  • Scrotoplasty (surgery to create a scrotum)

Top Surgery

Chest masculinization surgery, or top surgery, often involves removing breast tissue and reshaping the areola and nipple. There are two main types of chest masculinization surgeries:

  • Double-incision approach : Used to remove moderate to large amounts of breast tissue, this surgery involves two horizontal incisions below the breast to remove breast tissue and accentuate the contours of pectoral muscles. The nipples and areolas are removed and, in many cases, resized, reshaped, and replaced.
  • Short scar top surgery : For people with smaller breasts and firm skin, the procedure involves a small incision along the lower half of the areola to remove breast tissue. The nipple and areola may be resized before closing the incision.

Metoidioplasty

Some trans men elect to do metoidioplasty, also called a meta, which involves lengthening the clitoris to create a small penis. Both a penis and a clitoris are made of the same type of tissue and experience similar sensations.

Before metoidioplasty, testosterone therapy may be used to enlarge the clitoris. The procedure can be completed in one surgery, which may also include:

  • Constructing a glans (head) to look more like a penis
  • Extending the urethra (the tube urine passes through), which allows the person to urinate while standing
  • Creating a scrotum (scrotoplasty) from labia majora tissue

Phalloplasty

Other trans men opt for phalloplasty to give them a phallic structure (penis) with sensation. Phalloplasty typically requires several procedures but results in a larger penis than metoidioplasty.

The first and most challenging step is to harvest tissue from another part of the body, often the forearm or back, along with an artery and vein or two, to create the phallus, Nicholas Kim, MD, assistant professor in the division of plastic and reconstructive surgery in the department of surgery at the University of Minnesota Medical School in Minneapolis, told Health .

Those structures are reconnected under an operative microscope using very fine sutures—"thinner than our hair," said Dr. Kim. That surgery alone can take six to eight hours, he added.

In a separate operation, called urethral reconstruction, the surgeons connect the urinary system to the new structure so that urine can pass through it, said Dr. Kim. Urethral reconstruction, however, has a high rate of complications, which include fistulas or strictures.

According to Dr. Kim, some trans men prefer to skip that step, especially if standing to urinate is not a priority. People who want to have penetrative sex will also need prosthesis implant surgery.

Hysterectomy and Oophorectomy

Masculinizing surgery often includes the removal of the uterus (hysterectomy) and ovaries (oophorectomy). People may want a hysterectomy to address their dysphoria, said Dr. Wittenberg, and it may be necessary if their gender-affirming surgery involves removing the vagina.

Many also opt for an oophorectomy to remove the ovaries, almond-shaped organs on either side of the uterus that contain eggs and produce female sex hormones. In this case, oocytes (eggs) can be extracted and stored for a future surrogate pregnancy, if desired. However, this is a highly personal decision, and some trans men choose to keep their uterus to preserve fertility.

Feminizing Surgeries

Surgeries are often used to feminize facial features, enhance breast size and shape, reduce the size of an Adam’s apple , and reconstruct genitals.  Feminizing surgeries can include: 

  • Breast augmentation
  • Facial feminization surgery
  • Penis removal (penectomy)
  • Scrotum removal (scrotectomy)
  • Testicle removal (orchiectomy)
  • Tracheal shave (chondrolaryngoplasty) to reduce an Adam's apple
  • Vaginoplasty
  • Voice feminization

Breast Augmentation

Top surgery, also known as breast augmentation or breast mammoplasty, is often used to increase breast size for a more feminine appearance. The procedure can involve placing breast implants, tissue expanders, or fat from other parts of the body under the chest tissue.

Breast augmentation can significantly improve gender dysphoria. Studies show most people who undergo top surgery are happier, more satisfied with their chest, and would undergo the surgery again.

Most surgeons recommend 12 months of feminizing hormone therapy before breast augmentation. Since hormone therapy itself can lead to breast tissue development, transgender women may or may not decide to have surgical breast augmentation.

Facial Feminization and Adam's Apple Removal

Facial feminization surgery (FFS) is a series of plastic surgery procedures that reshape the forehead, hairline, eyebrows, nose, cheeks, and jawline. Nonsurgical treatments like cosmetic fillers, botox, fat grafting, and liposuction may also be used to create a more feminine appearance.  

Some trans women opt for chondrolaryngoplasty, also known as a tracheal shave. The procedure reduces the size of the Adam's apple, an area of cartilage around the larynx (voice box) that tends to be larger in people assigned male at birth.

Vulvoplasty and Vaginoplasty

As for bottom surgery, there are various feminizing procedures from which to choose. Vulvoplasty (to create external genitalia without a vagina) or vaginoplasty (to create a vulva and vaginal canal) are two of the most common procedures.

Dr. Wittenberg noted that people might undergo six to 12 months of electrolysis or laser hair removal before surgery to remove pubic hair from the skin that will be used for the vaginal lining.

Surgeons have different techniques for creating a vaginal canal. A common one is a penile inversion, where the masculine structures are emptied and inverted into a created cavity, explained Dr. Kim. Vaginoplasty may be done in one or two stages, said Dr. Wittenberg, and the initial recovery is three months—but it will be a full year until people see results.

Surgical removal of the penis or penectomy is sometimes used in feminization treatment. This can be performed along with an orchiectomy and scrotectomy.

However, a total penectomy is not commonly used in feminizing surgeries . Instead, many people opt for penile-inversion surgery, a technique that hollows out the penis and repurposes the tissue to create a vagina during vaginoplasty.

Orchiectomy and Scrotectomy

An orchiectomy is a surgery to remove the testicles —male reproductive organs that produce sperm. Scrotectomy is surgery to remove the scrotum, that sac just below the penis that holds the testicles.

However, some people opt to retain the scrotum. Scrotum skin can be used in vulvoplasty or vaginoplasty, surgeries to construct a vulva or vagina.

Other Surgical Options

Some gender non-conforming people opt for other types of surgeries. This can include:

  • Gender nullification procedures
  • Penile preservation vaginoplasty
  • Vaginal preservation phalloplasty

Gender Nullification

People who are agender or asexual may opt for gender nullification, sometimes called nullo. This involves the removal of all sex organs. The external genitalia is removed, leaving an opening for urine to pass and creating a smooth transition from the abdomen to the groin.

Depending on the person's sex assigned at birth, nullification surgeries can include:

  • Breast tissue removal
  • Nipple and areola augmentation or removal

Penile Preservation Vaginoplasty

Some gender non-conforming people assigned male at birth want a vagina but also want to preserve their penis, said Dr. Wittenberg. Often, that involves taking skin from the lining of the abdomen to create a vagina with full depth.

Vaginal Preservation Phalloplasty

Alternatively, a patient assigned female at birth can undergo phalloplasty (surgery to create a penis) and retain the vaginal opening. Known as vaginal preservation phalloplasty, it is often used as a way to resolve gender dysphoria while retaining fertility.

The recovery time for a gender affirmation surgery will depend on the type of surgery performed. For example, healing for facial surgeries may last for weeks, while transmasculine bottom surgery healing may take months.

Your recovery process may also include additional treatments or therapies. Mental health support and pelvic floor physiotherapy are a few options that may be needed or desired during recovery.

Risks and Complications

The risk and complications of gender affirmation surgeries will vary depending on which surgeries you have. Common risks across procedures could include:

  • Anesthesia risks
  • Hematoma, which is bad bruising
  • Poor incision healing

Complications from these procedures may be:

  • Acute kidney injury
  • Blood transfusion
  • Deep vein thrombosis, which is blood clot formation
  • Pulmonary embolism, blood vessel blockage for vessels going to the lung
  • Rectovaginal fistula, which is a connection between two body parts—in this case, the rectum and vagina
  • Surgical site infection
  • Urethral stricture or stenosis, which is when the urethra narrows
  • Urinary tract infection (UTI)
  • Wound disruption

What To Consider

It's important to note that an individual does not need surgery to transition. If the person has surgery, it is usually only one part of the transition process.

There's also psychotherapy . People may find it helpful to work through the negative mental health effects of dysphoria. Typically, people seeking gender affirmation surgery must be evaluated by a qualified mental health professional to obtain a referral.

Some people may find that living in their preferred gender is all that's needed to ease their dysphoria. Doing so for one full year prior is a prerequisite for many surgeries.

All in all, the entire transition process—living as your identified gender, obtaining mental health referrals, getting insurance approvals, taking hormones, going through hair removal, and having various surgeries—can take years, healthcare providers explained.

A Quick Review

Whether you're in the process of transitioning or supporting someone who is, it's important to be informed about gender affirmation surgeries. Gender affirmation procedures often involve multiple surgeries, which can be masculinizing, feminizing, or gender-nullifying in nature.

It is a highly personalized process that looks different for each person and can often take several months or years. The procedures also vary regarding risks and complications, so consultations with healthcare providers and mental health professionals are essential before having these procedures.

American Society of Plastic Surgeons. Gender affirmation surgeries .

Wright JD, Chen L, Suzuki Y, Matsuo K, Hershman DL. National estimates of gender-affirming surgery in the US .  JAMA Netw Open . 2023;6(8):e2330348-e2330348. doi:10.1001/jamanetworkopen.2023.30348

Coleman E, Radix AE, Bouman WP, et al. Standards of care for the health of transgender and gender diverse people, version 8 .  Int J Transgend Health . 2022;23(S1):S1-S260. doi:10.1080/26895269.2022.2100644 

Chou J, Kilmer LH, Campbell CA, DeGeorge BR, Stranix JY. Gender-affirming surgery improves mental health outcomes and decreases anti-depressant use in patients with gender dysphoria .  Plast Reconstr Surg Glob Open . 2023;11(6 Suppl):1. doi:10.1097/01.GOX.0000944280.62632.8c

Human Rights Campaign. Get the facts on gender-affirming care .

Human Rights Campaign. Transgender and non-binary people FAQ .

Unger CA. Hormone therapy for transgender patients . Transl Androl Urol . 2016;5(6):877–84. doi:10.21037/tau.2016.09.04

Richards JE, Hawley RS. Chapter 8: Sex Determination: How Genes Determine a Developmental Choice . In: Richards JE, Hawley RS, eds. The Human Genome . 3rd ed. Academic Press; 2011: 273-298.

Randolph JF Jr. Gender-affirming hormone therapy for transgender females . Clin Obstet Gynecol . 2018;61(4):705-721. doi:10.1097/GRF.0000000000000396

Cocchetti C, Ristori J, Romani A, Maggi M, Fisher AD. Hormonal treatment strategies tailored to non-binary transgender individuals . J Clin Med . 2020;9(6):1609. doi:10.3390/jcm9061609

Van Boerum MS, Salibian AA, Bluebond-Langner R, Agarwal C. Chest and facial surgery for the transgender patient .  Transl Androl Urol . 2019;8(3):219-227. doi:10.21037/tau.2019.06.18

Djordjevic ML, Stojanovic B, Bizic M. Metoidioplasty: techniques and outcomes . Transl Androl Urol . 2019;8(3):248–53. doi:10.21037/tau.2019.06.12

Bordas N, Stojanovic B, Bizic M, Szanto A, Djordjevic ML. Metoidioplasty: surgical options and outcomes in 813 cases .  Front Endocrinol . 2021;12:760284. doi:10.3389/fendo.2021.760284

Al-Tamimi M, Pigot GL, van der Sluis WB, et al. The surgical techniques and outcomes of secondary phalloplasty after metoidioplasty in transgender men: an international, multi-center case series .  The Journal of Sexual Medicine . 2019;16(11):1849-1859. doi:10.1016/j.jsxm.2019.07.027

Waterschoot M, Hoebeke P, Verla W, et al. Urethral complications after metoidioplasty for genital gender affirming surgery . J Sex Med . 2021;18(7):1271–9. doi:10.1016/j.jsxm.2020.06.023

Nikolavsky D, Hughes M, Zhao LC. Urologic complications after phalloplasty or metoidioplasty . Clin Plast Surg . 2018;45(3):425–35. doi:10.1016/j.cps.2018.03.013

Nota NM, den Heijer M, Gooren LJ. Evaluation and treatment of gender-dysphoric/gender incongruent adults . In: Feingold KR, Anawalt B, Boyce A, et al., eds.  Endotext . MDText.com, Inc.; 2000.

Carbonnel M, Karpel L, Cordier B, Pirtea P, Ayoubi JM. The uterus in transgender men . Fertil Steril . 2021;116(4):931–5. doi:10.1016/j.fertnstert.2021.07.005

Miller TJ, Wilson SC, Massie JP, Morrison SD, Satterwhite T. Breast augmentation in male-to-female transgender patients: Technical considerations and outcomes . JPRAS Open . 2019;21:63-74. doi:10.1016/j.jpra.2019.03.003

Claes KEY, D'Arpa S, Monstrey SJ. Chest surgery for transgender and gender nonconforming individuals . Clin Plast Surg . 2018;45(3):369–80. doi:10.1016/j.cps.2018.03.010

De Boulle K, Furuyama N, Heydenrych I, et al. Considerations for the use of minimally invasive aesthetic procedures for facial remodeling in transgender individuals .  Clin Cosmet Investig Dermatol . 2021;14:513-525. doi:10.2147/CCID.S304032

Asokan A, Sudheendran MK. Gender affirming body contouring and physical transformation in transgender individuals .  Indian J Plast Surg . 2022;55(2):179-187. doi:10.1055/s-0042-1749099

Sturm A, Chaiet SR. Chondrolaryngoplasty-thyroid cartilage reduction . Facial Plast Surg Clin North Am . 2019;27(2):267–72. doi:10.1016/j.fsc.2019.01.005

Chen ML, Reyblat P, Poh MM, Chi AC. Overview of surgical techniques in gender-affirming genital surgery . Transl Androl Urol . 2019;8(3):191-208. doi:10.21037/tau.2019.06.19

Wangjiraniran B, Selvaggi G, Chokrungvaranont P, Jindarak S, Khobunsongserm S, Tiewtranon P. Male-to-female vaginoplasty: Preecha's surgical technique . J Plast Surg Hand Surg . 2015;49(3):153-9. doi:10.3109/2000656X.2014.967253

Okoye E, Saikali SW. Orchiectomy . In: StatPearls [Internet] . Treasure Island (FL): StatPearls Publishing; 2022.

Salgado CJ, Yu K, Lalama MJ. Vaginal and reproductive organ preservation in trans men undergoing gender-affirming phalloplasty: technical considerations . J Surg Case Rep . 2021;2021(12):rjab553. doi:10.1093/jscr/rjab553

American Society of Plastic Surgeons. What should I expect during my recovery after facial feminization surgery?

American Society of Plastic Surgeons. What should I expect during my recovery after transmasculine bottom surgery?

de Brouwer IJ, Elaut E, Becker-Hebly I, et al. Aftercare needs following gender-affirming surgeries: findings from the ENIGI multicenter European follow-up study .  The Journal of Sexual Medicine . 2021;18(11):1921-1932. doi:10.1016/j.jsxm.2021.08.005

American Society of Plastic Surgeons. What are the risks of transfeminine bottom surgery?

American Society of Plastic Surgeons. What are the risks of transmasculine top surgery?

Khusid E, Sturgis MR, Dorafshar AH, et al. Association between mental health conditions and postoperative complications after gender-affirming surgery .  JAMA Surg . 2022;157(12):1159-1162. doi:10.1001/jamasurg.2022.3917

Related Articles

Masks Strongly Recommended but Not Required in Maryland, Starting Immediately

Due to the downward trend in respiratory viruses in Maryland, masking is no longer required but remains strongly recommended in Johns Hopkins Medicine clinical locations in Maryland. Read more .

  • Vaccines  
  • Masking Guidelines
  • Visitor Guidelines  

Couple talks with doctor.

Phalloplasty for Gender Affirmation

Featured Expert:

Fan Liang

Fan Liang, M.D.

Phalloplasty is surgery for masculinizing gender affirmation. Phalloplasty is a multistaged process that may include a variety of procedures, including:

  • Creating the penis
  • Lengthening the urethra so you are able to stand to urinate
  • Creating the tip (glans) of the penis
  • Creating the scrotum
  • Removing the vagina, uterus and ovaries
  • Placing erectile and testicular implants
  • Skin grafting from the donor tissue site 

Gender affirmation surgery is customized to each individual. Your surgical plan may include more or fewer of these steps and procedures. Fan Liang, M.D. , medical director of the Center for Transgender and Gender Expansive Health at Johns Hopkins, explains what you should know.

Are there different types of phalloplasty?

Phalloplasty involves using skin flaps, which are areas of skin moved from one area of the body to another. The skin flap is then reshaped, contoured and reattached to the groin to create the penis. There are three approaches the surgeon may use to construct the penis, using skin from the arm (radial forearm free flap), leg (anterolateral thigh flap) or side (latissimus dorsi flap). 

There are pros and cons to each approach. Factors for choosing skin flap locations include the patient’s health and fat distribution, nerve function, blood flow and desired surgical outcomes.

What is a radial forearm free flap?

A radial forearm free flap (RFFF) involves taking the skin, fat, nerves, arteries and veins from your wrist to about halfway up your forearm to create the penis. Typically, the surgeon will use your nondominant hand so it is easier for you to recover and return to your day-to-day activities.

During your surgical consultation, the doctor will check the blood flow to your arm and hand noninvasively. This involves temporarily putting pressure on arteries then releasing the pressure to test blood distribution in the arm and hand.

There are three stages to this procedure.

  • Stage 1: The first stage of an RFFF approach is creating the penis using tissue from the forearm. The area where the forearm tissue is taken will require a skin graft. This may occur at the time of the initial phalloplasty surgery, or it may occur three to five weeks afterward. If it occurs later, patients will have a temporary skin covering over the forearm to help it heal.
  • Stage 2: The second stage, scheduled about five to six months later, may include lengthening the urethra to allow for urination out of the tip of the penis, creating the scrotum and removing the vagina, and other procedures depending on the patient’s individualized plan.
  • Stage 3: The third stage of surgery involves putting in place testicle implants and an erectile device to help the patient achieve an erection. The third stage typically takes place 12 months after the second.

Will I have a say in how the phalloplasty is staged and the surgical plan?

Your gender affirmation surgery is highly personalized. Depending on what is most important to you, your surgery team will work with you on a customized plan beforehand. You and your surgeon will discuss your priorities and decide which procedures are right for you. Each stage will be scheduled to ensure your health and safety and provide the best chance of good results.

How long will I be in the hospital?

After your stage 1 surgery, you will stay as an inpatient for four to five days. Your surgical team will frequently monitor the blood supply to the tissue that has been used to create your new penis and ensure you are able to use the bathroom and walk around after surgery. Procedures for stages 2 and 3 do not require a hospital stay.

Will I need a catheter?

During your inpatient stay for stage 1 surgery, you will have a suprapubic tube that goes directly into your bladder and another catheter in your native urethra for at least five days. It is typically removed in the hospital before you go home.

If you decide not to have urethral lengthening as part of stage 2, you will have a Foley catheter placed in the operating room and removed before you leave the hospital. If you decide to have urethral lengthening, you will go home with a Foley catheter in the new urethra and a suprapubic tube. A clamp ensures that the urethra does not leak urine.

What is a suprapubic tube?

A suprapubic tube (SPT) allows urine to drain from your bladder. It is placed in the lower part of your abdomen, below the belly button. The SPT stays in for four to five weeks, depending on your healing and recovery.

When will my SPT be removed?

Before the SPT is removed, around four weeks after surgery, a urologist will perform a retrograde urethrogram. This involves putting dye into the bladder through the new urethra. An X-ray tracks the dye to see if the new urethra is open and ready for urination. If so, the doctor will clamp the SPT and you will be allowed to urinate from your new urethra. If everything looks good after a few days, the SPT is removed.

Forearm Flap Phalloplasty

Stage 1: phallus creation. Enlarged image .

Hillary Wilson's illustrations of gender affirming surgery detailing phalloplasty phallus creation.

Stage 2: urethral lengthening and scrotoplasty. Enlarged image .

Hillary Wilson's illustrations of gender affirming surgery detailing phalloplasty urethral lengthening and scrotoplasty.

Stage 3: penile prosthesis. Enlarged image .

Hillary Wilson's illustrations of gender affirming surgery detailing phalloplasty, penile prosthesis.

Other Skin Flaps Used in Phalloplasty

What is an anterolateral thigh flap.

An anterolateral thigh flap (ALT) uses skin, fat, nerves, arteries and veins from the leg to create a penis.  A special vascular CT scan can help the surgeon  examine the blood supply of each leg to determine which leg will be better for creating the skin flap.

The stage of the ALT phalloplasty are similar to the RFFF. The area where the thigh tissue is taken will also require a skin graft. The resulting scar on the thigh can be covered with shorts.

What is a musculocutaneous latissimus dorsi flap?

A musculocutaneous latissimus dorsi skin flap (MLD) involves the skin, fat, nerves, arteries and veins from the side of your back to create a penis. The surgeon may order a special CT scan to look at the blood flow throughout the donor site area.

The stages of the MLD phalloplasty are similar to the RFFF and ALT. However, the area from which the back tissue is taken usually does not require a skin graft and can be closed in a straight line. The scar can be covered with a shirt. Patients may experience some initial weakness raising their arm, but this improves with time.

How is penis size determined?

Penis size depends on patient preferences and the skin flap harvested from your body. Thinner patients with less fat on the skin flap will have a penis with less girth. Alternatively, patients with a greater amount of fat will have a thicker penis.

The length of the penis depends on the patient’s donor site, but typically it is about 5–6 inches. After the first stage, the penis may decrease in size as postoperative swelling decreases and the tissue settles into its new location.

What determines scrotum size?

Scrotum size is specific to the patient and depends on the amount of skin that is present in the genital area before phalloplasty. The more genital tissue there is, the larger the scrotum and the testicular implants can be.

There are different ways to create the scrotum, including a procedure called V-Y scrotoplasty, a technique that creates a pouch to hold testicular implants. AART silicone round carving blocks have been approved by the FDA to be used as implants.

Procedures to Discuss with Your Physician Before Phalloplasty

Each individual undergoing gender confirmation surgery is different. Your surgeon will work with you to discuss which procedures, and their timing, are best for you and your goals.

Should I have a hysterectomy before phalloplasty surgery?

For those interested in this procedure,  hysterectomies  are typically done before phalloplasty and do not require a vaginectomy.

Urethral Lengthening Before Phalloplasty

If you choose to have urethral lengthening, this procedure involves lengthening your existing urethra so that you are able to urinate out of the tip of the penis. It involves connecting your current urethra to the new urethra created in the shaft of the penis.

Not all patients choose to have urethral lengthening; however, this will be a necessary step if you want to stand when you urinate. It is also important to know that if you decide not to have urethral lengthening in stage 1 of your phalloplasty, it will not be possible to have the lengthening procedure later.

Complications of Urethral Lengthening

The most common complications for urethral lengthening include urethral strictures (narrowed areas of the urethra), fistula (creation of a passageway between the urethra and another location) and diverticula (formation of a pouch in the urethra). This may require an additional surgical procedure to fix.

What is a metoidioplasty?

A metoidioplasty is a surgical procedure to achieve masculine-appearing genitalia with fewer steps than a phalloplasty. The skin of the labia and around the clitoris is lengthened to achieve the appearance of a penis. Some people prefer to undergo a metoidioplasty if they do not want to use tissue from their arms or legs to create a penis or if they prefer a shorter, more straightforward surgery.

A metoidioplasty procedure has a quicker recovery and fewer complications. Surgeons can discuss metoidioplasty with patients and help them decide if this option is right for them.

Will I need to have hair removal?

Yes, before surgery, after you consult with the surgical team and choose a skin flap site, you will get a template for hair removal that you can give to your hair removal professional.

What if I have a tattoo on my preferred donor site?

As long as there is good blood flow and nerve function, donor sites — even those with a tattoo — can be used.

Penile Function and Sensation After Phalloplasty

What can i do with a reconstructed penis.

Penis function is determined by what you and your surgery team agree on for your surgical plan. If it is important for you to urinate out of the tip of your penis, then urethral lengthening may be a good choice for you. If sensation is most important, your team will focus on a donor site with good nerve innervation. If penetrative sex is most important, and you would like to maintain an erection, then implanting an erectile prosthetic can be part of your surgery plan.

Can I get an erection after phalloplasty?

In stage 3 phalloplasty, a urologist can place a prosthetic erectile device which will allow you to maintain an erection. As of September 2022, no implantable prosthetic devices have been FDA-approved for phalloplasty. Instead, the surgeon can use a device intended for patients with erectile dysfunction to allow transmasculine patients to achieve an erection. There is a risk of infection and implant rejection with an erectile implant . If this happens, it may take six months before another device can be placed into the penis.

What kind of sensation and feeling can I expect?

Sensation recovery varies by patient. Nerve regeneration can begin as early as three weeks after surgery, but it can take longer in some patients. Sometimes sensation can take up to a year or longer. Return of nerve sensation is not guaranteed. As nerves regenerate and strengthen connections, you might experience shooting pain, tingling or electrical sensations. As time goes on, the tingling feeling begins to subside.

What is nerve hookup during phalloplasty?

Nerve hookup involves taking existing nerves from the donor site, such as the arm, and connecting them to nerves located in the pelvis. This allows you to have sensation in the reconstructed penis.

What is clitoral burying during phalloplasty surgery?

Clitoral burying involves moving the clitoris into the base of the penis to increase sensation. This is typically done at stage 2.

Is orgasm possible after phalloplasty?

Orgasm is possible after phalloplasty, especially if your surgery plan emphasizes preserving sensation. It is important to note that your penis will not ejaculate with semen at the time of orgasm.

Find a Doctor

Specializing In:

  • Gender Affirmation Surgery
  • Transgender Health

At Another Johns Hopkins Member Hospital:

  • Howard County Medical Center
  • Sibley Memorial Hospital
  • Suburban Hospital

Find a Treatment Center

  • Center for Transgender and Gender Expansive Health
  • Plastic and Reconstructive Surgery

Find Additional Treatment Centers at:

Doctor speaks with smiling transgender woman

Request an Appointment

Doctor speaks with smiling transgender woman

Vaginoplasty for Gender Affirmation

Cropped shot of two affectionate young friends having a discussion while walking in the city

Top Surgery

how do they do gender reassignment surgery male to female

Facial Feminization Surgery (FFS)

Related Topics

  • Type 2 Diabetes
  • Heart Disease
  • Digestive Health
  • Multiple Sclerosis
  • Diet & Nutrition
  • Supplements
  • Health Insurance
  • Public Health
  • Patient Rights
  • Caregivers & Loved Ones
  • End of Life Concerns
  • Health News
  • Thyroid Test Analyzer
  • Doctor Discussion Guides
  • Hemoglobin A1c Test Analyzer
  • Lipid Test Analyzer
  • Complete Blood Count (CBC) Analyzer
  • What to Buy
  • Editorial Process
  • Meet Our Medical Expert Board

Preparation and Procedures Involved in Gender Affirmation Surgeries

If you or a loved one are considering gender affirmation surgery , you are probably wondering what steps you must go through before the surgery can be done. Let's look at what is required to be a candidate for these surgeries, the potential positive effects and side effects of hormonal therapy, and the types of surgeries that are available.

Gender affirmation surgery, also known as gender confirmation surgery, is performed to align or transition individuals with gender dysphoria to their true gender.

A transgender woman, man, or non-binary person may choose to undergo gender affirmation surgery.

The term "transexual" was previously used by the medical community to describe people who undergo gender affirmation surgery. The term is no longer accepted by many members of the trans community as it is often weaponized as a slur. While some trans people do identify as "transexual", it is best to use the term "transgender" to describe members of this community.

Transitioning

Transitioning may involve:

  • Social transitioning : going by different pronouns, changing one’s style, adopting a new name, etc., to affirm one’s gender
  • Medical transitioning : taking hormones and/or surgically removing or modifying genitals and reproductive organs

Transgender individuals do not need to undergo medical intervention to have valid identities.  

Reasons for Undergoing Surgery

Many transgender people experience a marked incongruence between their gender and their assigned sex at birth.   The American Psychiatric Association (APA) has identified this as gender dysphoria.

Gender dysphoria is the distress some trans people feel when their appearance does not reflect their gender. Dysphoria can be the cause of poor mental health or trigger mental illness in transgender people.

For these individuals, social transitioning, hormone therapy, and gender confirmation surgery permit their outside appearance to match their true gender.  

Steps Required Before Surgery

In addition to a comprehensive understanding of the procedures, hormones, and other risks involved in gender-affirming surgery, there are other steps that must be accomplished before surgery is performed. These steps are one way the medical community and insurance companies limit access to gender affirmative procedures.

Steps may include:

  • Mental health evaluation : A mental health evaluation is required to look for any mental health concerns that could influence an individual’s mental state, and to assess a person’s readiness to undergo the physical and emotional stresses of the transition.  
  • Clear and consistent documentation of gender dysphoria
  • A "real life" test :   The individual must take on the role of their gender in everyday activities, both socially and professionally (known as “real-life experience” or “real-life test”).

Firstly, not all transgender experience physical body dysphoria. The “real life” test is also very dangerous to execute, as trans people have to make themselves vulnerable in public to be considered for affirmative procedures. When a trans person does not pass (easily identified as their gender), they can be clocked (found out to be transgender), putting them at risk for violence and discrimination.

Requiring trans people to conduct a “real-life” test despite the ongoing violence out transgender people face is extremely dangerous, especially because some transgender people only want surgery to lower their risk of experiencing transphobic violence.

Hormone Therapy & Transitioning

Hormone therapy involves taking progesterone, estrogen, or testosterone. An individual has to have undergone hormone therapy for a year before having gender affirmation surgery.  

The purpose of hormone therapy is to change the physical appearance to reflect gender identity.

Effects of Testosterone

When a trans person begins taking testosterone , changes include both a reduction in assigned female sexual characteristics and an increase in assigned male sexual characteristics.

Bodily changes can include:

  • Beard and mustache growth  
  • Deepening of the voice
  • Enlargement of the clitoris  
  • Increased growth of body hair
  • Increased muscle mass and strength  
  • Increase in the number of red blood cells
  • Redistribution of fat from the breasts, hips, and thighs to the abdominal area  
  • Development of acne, similar to male puberty
  • Baldness or localized hair loss, especially at the temples and crown of the head  
  • Atrophy of the uterus and ovaries, resulting in an inability to have children

Behavioral changes include:

  • Aggression  
  • Increased sex drive

Effects of Estrogen

When a trans person begins taking estrogen , changes include both a reduction in assigned male sexual characteristics and an increase in assigned female characteristics.

Changes to the body can include:

  • Breast development  
  • Loss of erection
  • Shrinkage of testicles  
  • Decreased acne
  • Decreased facial and body hair
  • Decreased muscle mass and strength  
  • Softer and smoother skin
  • Slowing of balding
  • Redistribution of fat from abdomen to the hips, thighs, and buttocks  
  • Decreased sex drive
  • Mood swings  

When Are the Hormonal Therapy Effects Noticed?

The feminizing effects of estrogen and the masculinizing effects of testosterone may appear after the first couple of doses, although it may be several years before a person is satisfied with their transition.   This is especially true for breast development.

Timeline of Surgical Process

Surgery is delayed until at least one year after the start of hormone therapy and at least two years after a mental health evaluation. Once the surgical procedures begin, the amount of time until completion is variable depending on the number of procedures desired, recovery time, and more.

Transfeminine Surgeries

Transfeminine is an umbrella term inclusive of trans women and non-binary trans people who were assigned male at birth.

Most often, surgeries involved in gender affirmation surgery are broken down into those that occur above the belt (top surgery) and those below the belt (bottom surgery). Not everyone undergoes all of these surgeries, but procedures that may be considered for transfeminine individuals are listed below.

Top surgery includes:

  • Breast augmentation  
  • Facial feminization
  • Nose surgery: Rhinoplasty may be done to narrow the nose and refine the tip.
  • Eyebrows: A brow lift may be done to feminize the curvature and position of the eyebrows.  
  • Jaw surgery: The jaw bone may be shaved down.
  • Chin reduction: Chin reduction may be performed to soften the chin's angles.
  • Cheekbones: Cheekbones may be enhanced, often via collagen injections as well as other plastic surgery techniques.  
  • Lips: A lip lift may be done.
  • Alteration to hairline  
  • Male pattern hair removal
  • Reduction of Adam’s apple  
  • Voice change surgery

Bottom surgery includes:

  • Removal of the penis (penectomy) and scrotum (orchiectomy)  
  • Creation of a vagina and labia

Transmasculine Surgeries

Transmasculine is an umbrella term inclusive of trans men and non-binary trans people who were assigned female at birth.

Surgery for this group involves top surgery and bottom surgery as well.

Top surgery includes :

  • Subcutaneous mastectomy/breast reduction surgery.
  • Removal of the uterus and ovaries
  • Creation of a penis and scrotum either through metoidioplasty and/or phalloplasty

Complications and Side Effects

Surgery is not without potential risks and complications. Estrogen therapy has been associated with an elevated risk of blood clots ( deep vein thrombosis and pulmonary emboli ) for transfeminine people.   There is also the potential of increased risk of breast cancer (even without hormones, breast cancer may develop).

Testosterone use in transmasculine people has been associated with an increase in blood pressure, insulin resistance, and lipid abnormalities, though it's not certain exactly what role these changes play in the development of heart disease.  

With surgery, there are surgical risks such as bleeding and infection, as well as side effects of anesthesia . Those who are considering these treatments should have a careful discussion with their doctor about potential risks related to hormone therapy as well as the surgeries.  

Cost of Gender Confirmation Surgery

Surgery can be prohibitively expensive for many transgender individuals. Costs including counseling, hormones, electrolysis, and operations can amount to well over $100,000. Transfeminine procedures tend to be more expensive than transmasculine ones. Health insurance sometimes covers a portion of the expenses.

Quality of Life After Surgery

Quality of life appears to improve after gender-affirming surgery for all trans people who medically transition. One 2017 study found that surgical satisfaction ranged from 94% to 100%.  

Since there are many steps and sometimes uncomfortable surgeries involved, this number supports the benefits of surgery for those who feel it is their best choice.

A Word From Verywell

Gender affirmation surgery is a lengthy process that begins with counseling and a mental health evaluation to determine if a person can be diagnosed with gender dysphoria.

After this is complete, hormonal treatment is begun with testosterone for transmasculine individuals and estrogen for transfeminine people. Some of the physical and behavioral changes associated with hormonal treatment are listed above.

After hormone therapy has been continued for at least one year, a number of surgical procedures may be considered. These are broken down into "top" procedures and "bottom" procedures.

Surgery is costly, but precise estimates are difficult due to many variables. Finding a surgeon who focuses solely on gender confirmation surgery and has performed many of these procedures is a plus.   Speaking to a surgeon's past patients can be a helpful way to gain insight on the physician's practices as well.

For those who follow through with these preparation steps, hormone treatment, and surgeries, studies show quality of life appears to improve. Many people who undergo these procedures express satisfaction with their results.

Bizic MR, Jeftovic M, Pusica S, et al. Gender dysphoria: Bioethical aspects of medical treatment . Biomed Res Int . 2018;2018:9652305. doi:10.1155/2018/9652305

American Psychiatric Association. What is gender dysphoria? . 2016.

The World Professional Association for Transgender Health. Standards of care for the health of transsexual, transgender, and gender-nonconforming people . 2012.

Tomlins L. Prescribing for transgender patients . Aust Prescr . 2019;42(1): 10–13.  doi:10.18773/austprescr.2019.003

T'sjoen G, Arcelus J, Gooren L, Klink DT, Tangpricha V. Endocrinology of transgender medicine . Endocr Rev . 2019;40(1):97-117. doi:10.1210/er.2018-00011

Unger CA. Hormone therapy for transgender patients . Transl Androl Urol . 2016;5(6):877-884.  doi:10.21037/tau.2016.09.04

Seal LJ. A review of the physical and metabolic effects of cross-sex hormonal therapy in the treatment of gender dysphoria . Ann Clin Biochem . 2016;53(Pt 1):10-20.  doi:10.1177/0004563215587763

Schechter LS. Gender confirmation surgery: An update for the primary care provider . Transgend Health . 2016;1(1):32-40. doi:10.1089/trgh.2015.0006

Altman K. Facial feminization surgery: current state of the art . Int J Oral Maxillofac Surg . 2012;41(8):885-94.  doi:10.1016/j.ijom.2012.04.024

Therattil PJ, Hazim NY, Cohen WA, Keith JD. Esthetic reduction of the thyroid cartilage: A systematic review of chondrolaryngoplasty . JPRAS Open. 2019;22:27-32. doi:10.1016/j.jpra.2019.07.002

Top H, Balta S. Transsexual mastectomy: Selection of appropriate technique according to breast characteristics . Balkan Med J . 2017;34(2):147-155. doi:10.4274/balkanmedj.2016.0093

Chan W, Drummond A, Kelly M. Deep vein thrombosis in a transgender woman . CMAJ . 2017;189(13):E502-E504.  doi:10.1503/cmaj.160408

Streed CG, Harfouch O, Marvel F, Blumenthal RS, Martin SS, Mukherjee M. Cardiovascular disease among transgender adults receiving hormone therapy: A narrative review . Ann Intern Med . 2017;167(4):256-267. doi:10.7326/M17-0577

Hashemi L, Weinreb J, Weimer AK, Weiss RL. Transgender care in the primary care setting: A review of guidelines and literature . Fed Pract . 2018;35(7):30-37.

Van de grift TC, Elaut E, Cerwenka SC, Cohen-kettenis PT, Kreukels BPC. Surgical satisfaction, quality of life, and their association after gender-affirming aurgery: A follow-up atudy . J Sex Marital Ther . 2018;44(2):138-148. doi:10.1080/0092623X.2017.1326190

American Society of Plastic Surgeons. Gender confirmation surgeries .

American Psychological Association. Transgender people, gender identity, and gender expression .

Colebunders B, Brondeel S, D'Arpa S, Hoebeke P, Monstrey S. An update on the surgical treatment for transgender patients . Sex Med Rev . 2017 Jan;5(1):103-109. doi:10.1016/j.sxmr.2016.08.001

Learn how UpToDate can help you.

Select the option that best describes you

  • Medical Professional
  • Resident, Fellow, or Student
  • Hospital or Institution
  • Group Practice
  • Patient or Caregiver
  • Find in topic

RELATED TOPICS

INTRODUCTION

This topic will review surgeries that are commonly performed as part of feminizing transition. Other topics related to the care of transgender persons include:

● (See "Transgender men: Evaluation and management" .)

● (See "Transgender women: Evaluation and management" .)

● (See "Primary care of transgender individuals" .)

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • View all journals
  • Explore content
  • About the journal
  • Publish with us
  • Sign up for alerts
  • Review Article
  • Published: 16 May 2017

An overview of female-to-male gender-confirming surgery

  • Shane D. Morrison 1 ,
  • Mang L. Chen 2 &
  • Curtis N. Crane 2  

Nature Reviews Urology volume  14 ,  pages 486–500 ( 2017 ) Cite this article

2668 Accesses

62 Citations

13 Altmetric

Metrics details

  • Reconstruction
  • Sexual behaviour

Gender-confirming surgery is becoming a more frequently encountered procedure for urologists, plastic surgeons, and gynaecologists

Female-to-male gender-confirming surgery consists of facial masculinization, chest masculinization, body contouring, and genital surgery

Metoidioplasty (hypertrophy with systemic hormones and mobilization of the clitoris with urethroplasty) can produce a sensate microphallus

Phalloplasty can produce an aesthetic and sensate phallus with ability to micturate in a standing position and engage in penetrative sexual intercourse if proper nerve coaptation and prosthetic insertion are performed

Urethral complications following genital surgery in transmen are generally higher than 30% and include urethral fistulas and strictures; revisional urethroplasty can address most urethral complications following genital surgery

Advances in basic sciences, transgender-specific prostheses, and patient-reported outcomes will continue to offer options for improvements in gender-confirming surgery

Gender dysphoria is estimated to occur in approximately 25 million people worldwide, and can have severe psychosocial sequelae. Medical and surgical gender transition can substantially improve quality-of-life outcomes for individuals with gender dysphoria. Individuals seeking to undergo female-to-male (FtM) transition have various surgical options available for gender confirmation, including facial and chest masculinization, body contouring, and genital surgery. The World Professional Association for Transgender Health guidelines should be met before the patient undergoes surgery, to ensure that gender-confirming surgery is appropriate and indicated. Chest masculinization and metoidioplasty or phalloplasty are the most common procedures pursued, and both generally result in high levels of patient satisfaction. Phalloplasty, with a resultant aesthetic and sensate phallus along with implantable prosthetic, can take upwards of a year to accomplish, and is associated with a considerable risk of complications. Urethral complications are most frequent, and can be addressed with revision procedures. A number of scaffolds, implants, and prostheses are now in development to improve outcomes in FtM patients.

This is a preview of subscription content, access via your institution

Access options

Access Nature and 54 other Nature Portfolio journals

Get Nature+, our best-value online-access subscription

24,99 € / 30 days

cancel any time

Subscribe to this journal

Receive 12 print issues and online access

195,33 € per year

only 16,28 € per issue

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF

Prices may be subject to local taxes which are calculated during checkout

how do they do gender reassignment surgery male to female

Similar content being viewed by others

how do they do gender reassignment surgery male to female

Male-to-female gender affirmation surgery: breast reconstruction with Ergonomix round prostheses

how do they do gender reassignment surgery male to female

Overview on metoidioplasty: variants of the technique

how do they do gender reassignment surgery male to female

Masculinizing genital gender-affirming surgery: metoidioplasty and urethral lengthening

World Professional Association for Transgender Health. Standards of Care for the Health of Transsexual, Transgender, and Gender Nonconforming People. 7th Version (World Professional Association for Transgender Health, 2011). Standards of care for transgender and gender nonconforming patients to assist all providers caring for patients within this population.

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders 5th edn (American Psychiatric Association, 2013).

Benjamin, H. The Transsexual Phenomenon (Julian Press, 1966).

Google Scholar  

Byne, W. et al . Report of the American Psychiatric Association task force on treatment of gender identity disorder. Arch. Sex. Behav. 41 , 759–796 (2012).

Article   PubMed   Google Scholar  

Dhejne, C. et al . Long-term follow-up of transsexual persons undergoing sex reassignment surgery: cohort study in Sweden. PLoS ONE 6 , e16885 (2011).

Article   CAS   PubMed   PubMed Central   Google Scholar  

Dhejne, C., Oberg, K., Arver, S. & Landen, M. An analysis of all applications for sex reassignment surgery in Sweden, 1960-2010: prevalence, incidence, and regrets. Arch. Sex. Behav. 43 , 1535–1545 (2014).

Lawrence, A. A. Gender assignment dysphoria in the DSM-5. Arch. Sex. Behav. 43 , 1263–1266 (2014).

Leiter, E., Futterweit, W. & Brown, G. R. in Reconstructive Urology Vol. 2 (eds Webster, G., Kirby, R., King, L. & Goldwasser, B.) 921–932 (Blackwell Scientific Publications, 1993).

Winter, S. et al . Transgender people: health at the margins of society. Lancet 388 , 390–400 (2016). Evaluation of the difficulties experienced by transgender patients in seeking healthcare.

Wylie, K. et al . Serving transgender people: clinical care considerations and service delivery models in transgender health. Lancet 388 , 401–411 (2016).

Gooren, L. J. Clinical practice. Care of transsexual persons. N. Engl. J. Med. 364 , 1251–1257 (2011).

Article   CAS   PubMed   Google Scholar  

Deutsch, M. B. et al . Electronic medical records and the transgender patient: recommendations from the World Professional Association for Transgender Health EMR Working Group. J. Am. Med. Inform. Assoc. 20 , 700–703 (2013).

Article   PubMed   PubMed Central   Google Scholar  

Morrison, S. D. The care transition in plastic surgery. Plast. Reconstr. Surg. 136 , 861e–862e (2015).

Morrison, S. D. & Swanson, J. W. Surgical justice. Plast. Reconstr. Surg. 136 , 291e–292e (2015).

De Cuypere, G., Elaut, E. & Heylens, G. Long-term follow-up: psychosocial outcome of Belgian transsexuals after sex reassignment surgery. Sexologies 15 , 126–133 (2006).

Article   Google Scholar  

De Cuypere, G. et al . Sexual and physical health after sex reassignment surgery. Arch. Sex. Behav. 34 , 679–690 (2005).

Hage, J. J. & Karim, R. B. Ought GIDNOS get nought? Treatment options for nontranssexual gender dysphoria. Plast. Reconstr. Surg. 105 , 1222–1227 (2000).

Lawrence, A. A. Sexuality before and after male-to-female sex reassignment surgery. Arch. Sex. Behav. 34 , 147–166 (2005).

Wierckx, K. et al . Sexual desire in female-to-male transsexual persons: exploration of the role of testosterone administration. Eur. J. Endocrinol. 165 , 331–337 (2011).

Wierckx, K. et al . Sexual desire in trans persons: associations with sex reassignment treatment. J. Sex. Med. 11 , 107–118 (2014). Evaluation of the sexual desires experienced by transgender patients after gender-confirming surgery.

Wierckx, K. et al . Long-term evaluation of cross-sex hormone treatment in transsexual persons. J. Sex. Med. 9 , 2641–2651 (2012).

Wierckx, K. et al . Quality of life and sexual health after sex reassignment surgery in transsexual men. J. Sex. Med. 8 , 3379–3388 (2011).

Zaker-Shahrak, A., Chio, L. W., Isaac, R. & Tescher, J. Economic impact assessment: Gender nondiscrimination in health insurance. (ed. Department of Insurance) (State of California, 2012).

Monstrey, S. et al . Surgical therapy in transsexual patients: a multi-disciplinary approach. Acta Chir. Belg. 101 , 200–209 (2001).

CAS   PubMed   Google Scholar  

Selvaggi, G., Dhejne, C., Landen, M. & Elander, A. The 2011 WPATH standards of care and penile reconstruction in female-to-male transsexual individuals. Adv. Urol. 2012 , 581712 (2012).

Gooren, L. J. Management of female-to-male transgender persons: medical and surgical management, life expectancy. Curr. Opin. Endocrinol. Diabetes Obes. 21 , 233–238 (2014).

Davis, S. R. et al . Testosterone for low libido in postmenopausal women not taking estrogen. N. Engl. J. Med. 359 , 2005–2017 (2008).

Gooren, L. J. & Giltay, E. J. Review of studies of androgen treatment of female-to-male transsexuals: effects and risks of administration of androgens to females. J. Sex. Med. 5 , 765–776 (2008).

Gooren, L. J., Giltay, E. J. & Bunck, M. C. Long-term treatment of transsexuals with cross-sex hormones: extensive personal experience. J. Clin. Endocrinol. Metab. 93 , 19–25 (2008).

Mueller, A. & Gooren, L. Hormone-related tumors in transsexuals receiving treatment with cross-sex hormones. Eur. J. Endocrinol. 159 , 197–202 (2008).

Van Caenegem, E. et al . Bone mass, bone geometry, and body composition in female-to-male transsexual persons after long-term cross-sex hormonal therapy. J. Clin. Endocrinol. Metab. 97 , 2503–2511 (2012).

Monstrey, S. J., Ceulemans, P. & Hoebeke, P. Sex reassignment surgery in the female-to-male transsexual. Semin. Plast. Surg. 25 , 229–244 (2011).

Morrison, S. D., Perez, M. G., Carter, C. K. & Crane, C. N. Pre- and post-operative care with associated intra-operative techniques for phalloplasty in female-to-male patients. Urol. Nurs. 35 , 134–138 (2015).

Morrison, S. D., Perez, M. G., Nedelman, M. & Crane, C. N. Current state of female-to-male gender confirming surgery. Curr. Sex. Health Rep. 7 , 38–48 (2015).

Selvaggi, G. & Bellringer, J. Gender reassignment surgery: an overview. Nat. Rev. Urol. 8 , 274–282 (2011).

Morrison, S. D. et al . Educational exposure to transgender patient care in plastic surgery training. Plast. Reconstr. Surg. 138 , 944–953 (2016). Evaluation of resident exposure to transgender patient care in plastic surgery.

Obedin-Maliver, J. et al . Lesbian, gay, bisexual, and transgender-related content in undergraduate medical education. JAMA 306 , 971–977 (2011).

Dy, G. W. et al . Exposure to and attitudes regarding transgender education among urology residents. J. Sex. Med. 13 , 1466–1472 (2016). Evaluation of resident exposure to transgender patient care in urology.

Morrison, S. D. et al . Facial feminization: systematic review of the literature. Plast. Reconstr. Surg. 137 , 1759–1770 (2016).

Ousterhout, D. K. Dr. Paul Tessier and facial skeletal masculinization. Ann. Plast. Surg. 67 , S10–S15 (2011).

Deschamps-Braly, J. C., Sacher, C. L., Fick, J. & Ousterhout, D. K. First female-to-male facial confirmation surgery with description of a new procedure for masculinization of the thyroid cartilage (Adam's apple). Plast. Reconstr. Surg. 139 , 883e–887e (2017). First report of facial masculinization in transmen.

Monstrey, S. et al . Chest-wall contouring surgery in female-to-male transsexuals: a new algorithm. Plast. Reconstr. Surg. 121 , 849–859 (2008). Algorithmic approach to chest wall masculinization.

Richards, C. & Barrett, J. The case for bilateral mastectomy and male chest contouring for the female-to-male transsexual. Ann. R. Coll. Surg. Engl. 95 , 93–95 (2013).

Berry, M. G., Curtis, R. & Davies, D. Female-to-male transgender chest reconstruction: a large consecutive, single-surgeon experience. J. Plast. Reconstr. Aesthet. Surg. 65 , 711–719 (2012).

Colic, M. M. & Colic, M. M. Circumareolar mastectomy in female-to-male transsexuals and large gynecomastias: a personal approach. Aesthetic Plast. Surg. 24 , 450–454 (2000).

Nelson, L., Whallett, E. J. & McGregor, J. C. Transgender patient satisfaction following reduction mammaplasty. J. Plast. Reconstr. Aesthet. Surg. 62 , 331–334 (2009).

Vukadinovic, V., Stojanovic, B., Majstorovic, M. & Milosevic, A. The role of clitoral anatomy in female to male sex reassignment surgery. ScientificWorldJournal 2014 , 437378 (2014).

Weyers, S. et al . Gynaecological aspects of the treatment and follow-up of transsexual men and women. Facts Views Vis. Obgyn. 2 , 35–54 (2010).

CAS   PubMed   PubMed Central   Google Scholar  

Ergeneli, M. H., Duran, E. H., Ozcan, G. & Erdogan, M. Vaginectomy and laparoscopically assisted vaginal hysterectomy as adjunctive surgery for female-to-male transsexual reassignment: preliminary report. Eur. J. Obstet. Gynecol. Reprod. Biol. 87 , 35–37 (1999).

Weyers, S., Selvaggi, G. & Monstrey, S. Two-stage versus one-stage sex reassignment surgery in female-to-male transsexual individuals. Gynecol. Surg. 3 , 190–194 (2006).

Morrison, S. D. et al . Phalloplasty: a review of techniques and outcomes. Plast. Reconstr. Surg. 138 , 594–615 (2016). Contemporary evaluation of techniques and outcomes of phalloplasty.

Perrone, A. M. et al . Hysterectomy and bilateral salpingoovariectomy in a transsexual subject without visible scaring. Diagn. Ther. Endosc. 2010 , 845029 (2010).

Chen, Y. J. et al . Single-port compared with conventional laparoscopic-assisted vaginal hysterectomy: a randomized controlled trial. Obstet. Gynecol. 117 , 906–912 (2011).

Bogliolo, S. et al . Robotic single-site surgery for female-to-male transsexuals: preliminary experience. ScientificWorldJournal 2014 , 674579 (2014).

Obedin-Maliver, J., Light, A., Dehaan, G., Steinauer, J. & Jackson, R. Vaginal hysterectomy as a viable option for female-to-male transgender men. Obstet. Gynecol. 123 (Suppl. 1), 126S–127S (2014).

Djordjevic, M. L. et al . Urethral lengthening in metoidioplasty (female-to-male sex reassignment surgery) by combined buccal mucosa graft and labia minora flap. Urology 74 , 349–353 (2009).

Djordjevic, M. L. & Bizic, M. R. Comparison of two different methods for urethral lengthening in female to male (metoidioplasty) surgery. J. Sex. Med. 10 , 1431–1438 (2013). Assessment of outcomes of urethral lengthening following metoidioplasty.

Zhang, Y. F. et al . Is vaginal mucosal graft the excellent substitute material for urethral reconstruction in female-to-male transsexuals? World J. Urol. 33 , 2115–2123 (2015).

Hage, J. J. & Bloem, J. J. Review of the literature on construction of a neourethra in female-to-male transsexuals. Ann. Plast. Surg. 30 , 278–286 (1993).

Hage, J. J., Bouman, F. G. & Bloem, J. J. Construction of the fixed part of the neourethra in female-to-male transsexuals: experience in 53 patients. Plast. Reconstr. Surg. 91 , 904–910 (1993).

Rohrmann, D. & Jakse, G. Urethroplasty in female-to-male transsexuals. Eur. Urol. 44 , 611–614 (2003).

Selvaggi, G. & Elander, A. Penile reconstruction/formation. Curr. Opin. Urol. 18 , 589–597 (2008).

Salgado, C. J., Chim, H., Tang, J. C., Monstrey, S. J. & Mardini, S. Penile reconstruction. Semin. Plast. Surg. 25 , 221–228 (2011).

Hage, J. J. & De Graaf, F. H. Addressing the ideal requirements by free flap phalloplasty: some reflections on refinements of technique. Microsurgery 14 , 592–598 (1993).

Monstrey, S. et al . Penile reconstruction: is the radial forearm flap really the standard technique? Plast. Reconstr. Surg. 124 , 510–518 (2009). Largest evaluation of outcomes of RFFF phalloplasty.

Zhang, W. R., Garrett, G. L., Arron, S. T. & Garcia, M. M. Laser hair removal for genital gender affirming surgery. Transl Androl. Urol. 5 , 381–387 (2016).

Durfee, R. & Rowland, W. in Proceedings of the Second Interdisciplinary Symposium on Gender Dysphoria Syndrome (eds Laub, D. R. & Gandy, P.) 181–183 (Stanford Univ. Press, 1973).

Lebovic, G. S. & Laub, D. R. in Reconstructive and Plastic Surgery of the External Genitalia (eds Ehrlich, R. M. & Alter, G. J.) 355–360 (WB Saunders, 1999).

Hage, J. J. Metaidoioplasty: an alternative phalloplasty technique in transsexuals. Plast. Reconstr. Surg. 97 , 161–167 (1996).

Hage, J. J. & van Turnhout, A. A. Long-term outcome of metaidoioplasty in 70 female-to-male transsexuals. Ann. Plast. Surg. 57 , 312–316 (2006).

Oakley, S. H. et al . Innervation and histology of the clitoral-urethal complex: a cross-sectional cadaver study. J. Sex. Med. 10 , 2211–2218 (2013).

Djordjevic, M. L. et al . Metoidioplasty as a single stage sex reassignment surgery in female transsexuals: Belgrade experience. J. Sex. Med. 6 , 1306–1313 (2009).

Perovic, S. V. & Djordjevic, M. L. Metoidioplasty: a variant of phalloplasty in female transsexuals. BJU Int. 92 , 981–985 (2003).

Takamatsu, A. & Harashina, T. Labial ring flap: a new flap for metaidoioplasty in female-to-male transsexuals. J. Plast. Reconstr. Aesthet. Surg. 62 , 318–325 (2009).

Bogoras, N. Über die volle plastische Wiederherstellung eines zum Koitus fähigen Penis (Peniplastica totalis) [German]. Zentralbl. Chir. 63 , 1271–1276 (1936).

Gillies, H. & Millard, R. The Principles and Art of Plastic Surgery Vol. II 369–388 (Little, Brown and Company, 1957).

Kaplan, I. A rapid method for constructing a functional sensitive penis. Br. J. Plast. Surg. 24 , 342–344 (1971).

Puckett, C. L., Reinisch, J. F. & Montie, J. E. Free flap phalloplasty. J. Urol. 128 , 294–297 (1982).

Hu, W. et al . A preliminary report of penile transplantation: part 2. Eur. Urol. 50 , 1115–1116 (2006).

Hu, W. et al . A preliminary report of penile transplantation. Eur. Urol. 50 , 851–853 (2006).

Morrison, S. D. et al . Penile replantation: a retrospective analysis of outcomes and complications. J. Reconstr. Microsurg. 33 , 227–232 (2017).

Monstrey, S. et al . Radial forearm phalloplasty: a review of 81 cases. Eur. J. Plast. Surg. 28 , 206–212 (2005).

Bettocchi, C., Ralph, D. J. & Pryor, J. P. Pedicled pubic phalloplasty in females with gender dysphoria. BJU Int. 95 , 120–124 (2005).

Shaeer, O. & El-Sebaie, A. Construction of neoglans penis: a new sculpturing technique from rectus abdominis myofascial flap. J. Sex. Med. 2 , 259–265 (2005).

Terrier, J. E., Courtois, F., Ruffion, A. & Morel Journel, N. Surgical outcomes and patients' satisfaction with suprapubic phalloplasty. J. Sex. Med. 11 , 288–298 (2014).

Alanis, S. Z. An innovation in total penis reconstruction. Plast. Reconstr. Surg. 43 , 418–422 (1969).

Davies, D. Phalloplasty. S. Afr. Med. J. 31 , 990–991 (1957).

Davies, D. M. & Matti, B. A. A method of phalloplasty using the deep inferior epigastric flap. Br. J. Plast. Surg. 41 , 165–168 (1988).

Dubin, B. J., Sato, R. M. & Laub, D. R. Results of phalloplasty. Plast. Reconstr. Surg. 64 , 163–170 (1979).

Santi, P. et al . Immediate reconstruction of the penis using an inferiorly based rectus abdominis myocutaneous flap. Plast. Reconstr. Surg. 81 , 961–964 (1988).

Zhang, Y., Lu, L., Zhang, W., Jiang, H. & Zhu, X. A simple and effective method for phalloplasty in female-to-male transsexuals. Plast. Reconstr. Surg. 126 , 264e–265e (2010).

Lumen, N., Hoebeke, P. & Oosterlinck, W. Urethroplasty for urethral strictures: quality assessment of an in-home algorithm. Int. J. Urol. 17 , 167–174 (2010).

Krauss, E. M., Tung, T. H. & Moore, A. M. Free functional muscle transfers to restore upper extremity function. Hand Clin. 32 , 243–256 (2016).

Ranno, R. et al . Neo-phalloplasty with re-innervated latissimus dorsi free flap: a functional study of a novel technique. Acta Chir. Plast. 49 , 3–7 (2007).

Ranno, R., Hyza, P., Vesely, J., Dessy, L. A. & Kadanka, Z. An objective evaluation of contraction power of neo-phallus reconstructed with free re-innervated LD in female-to-male transsexuals. Acta Chir. Plast. 49 , 8–12 (2007).

Mori, R. L. & Angermeier, K. W. Staged urethroplasty in the management of complex anterior urethral stricture disease. Transl Androl. Urol. 4 , 29–34 (2015).

PubMed   PubMed Central   Google Scholar  

Djordjevic, M. L., Bumbasirevic, M. Z., Vukovic, P. M., Sansalone, S. & Perovic, S. V. Musculocutaneous latissimus dorsi free transfer flap for total phalloplasty in children. J. Pediatr. Urol. 2 , 333–339 (2006).

Lin, C. T. & Chen, L. W. Using a free thoracodorsal artery perforator flap for phallic reconstruction — a report of surgical technique. J. Plast. Reconstr. Aesthet. Surg. 62 , 402–408 (2009).

Perovic, S. V., Djinovic, R., Bumbasirevic, M., Djordjevic, M. & Vukovic, P. Total phalloplasty using a musculocutaneous latissimus dorsi flap. BJU Int. 100 , 899–905 (2007).

Vesely, J. et al . New technique of total phalloplasty with reinnervated latissimus dorsi myocutaneous free flap in female-to-male transsexuals. Ann. Plast. Surg. 58 , 544–550 (2007).

Kessler, T. M. et al . Long-term results of surgery for urethral stricture: a statistical analysis. J. Urol. 170 , 840–844 (2003).

Mathur, R. K. et al . Single-stage preputial skin flap urethroplasty for long-segment urethral strictures: evaluation and determinants of success. BJU Int. 113 , 120–126 (2014).

Taguchi, H., Saito, K. & Yamada, T. A simple method of total reconstruction of the penis. Case reports. Plast. Reconstr. Surg. 60 , 454–456 (1977).

Hage, J. J., Winters, H. A. & Van Lieshout, J. Fibula free flap phalloplasty: modifications and recommendations. Microsurgery 17 , 358–365 (1996).

Sadove, R. C., Sengezer, M., McRoberts, J. W. & Wells, M. D. One-stage total penile reconstruction with a free sensate osteocutaneous fibula flap. Plast. Reconstr. Surg. 92 , 1314–1323 (1993).

McRoberts, J. W. & Sadove, R. C. Penile reconstruction with a free sensate osteocutaneous fibula flap in the surgical management of the intersex patient. Adv. Exp. Med. Biol. 511 , 283–287 (2002).

Sengezer, M., Ozturk, S., Deveci, M. & Odabasi, Z. Long-term follow-up of total penile reconstruction with sensate osteocutaneous free fibula flap in 18 biological male patients. Plast. Reconstr. Surg. 114 , 439–450 (2004).

Dabernig, J., Chan, L. K. & Schaff, J. Phalloplasty with free (septocutaneous) fibular flap sine fibula. J. Urol. 176 , 2085–2088 (2006).

Papadopulos, N. A., Schaff, J. & Biemer, E. The use of free prelaminated and sensate osteofasciocutaneous fibular flap in phalloplasty. Injury 39 (Suppl. 3), S62–S67 (2008).

Salgado, C. J., Rampazzo, A., Xu, E. & Chen, H. C. Treatment of dyspareunia by creation of a pseudojoint in rigid bone following total penile reconstruction with fibular osteocutaneous flap. J. Sex. Med. 5 , 2947–2950 (2008).

Sun, G. C. & Huang, J. J. One-stage reconstruction of the penis with composite iliac crest and lateral groin skin flap. Ann. Plast. Surg. 15 , 519–528 (1985).

Cutting, C. B. & McCarthy, J. G. Comparison of residual osseous mass between vascularized and nonvascularized onlay bone transfers. Plast. Reconstr. Surg. 72 , 672–675 (1983).

Weiland, A. J., Phillips, T. W. & Randolph, M. A. Bone grafts: a radiologic, histologic, and biomechanical model comparing autografts, allografts, and free vascularized bone grafts. Plast. Reconstr. Surg. 74 , 368–379 (1984).

Zielinski, T. Phalloplasty using a lateral groin flap in female-to-male transsexuals. Acta Chir. Plast. 41 , 15–19 (1999).

Akoz, T., Erdogan, B., Gorgu, M., Kapucu, M. R. & Kargi, E. Penile reconstruction in children using a double vascular pedicle composite groin flap. Scand. J. Urol. Nephrol. 32 , 225–230 (1998).

Akoz, T. & Kargi, E. Phalloplasty in a female-to-male transsexual using a double-pedicle composite groin flap. Ann. Plast. Surg. 48 , 423–427 (2002).

Puckett, C. L. & Montie, J. E. Construction of male genitalia in the transsexual, using a tubed groin flap for the penis and a hydraulic inflation device. Plast. Reconstr. Surg. 61 , 523–530 (1978).

Felici, N. & Felici, A. A new phalloplasty technique: the free anterolateral thigh flap phalloplasty. J. Plast. Reconstr. Aesthet. Surg. 59 , 153–157 (2006).

Lee, G. K., Lim, A. F. & Bird, E. T. A novel single-flap technique for total penile reconstruction: the pedicled anterolateral thigh flap. Plast. Reconstr. Surg. 124 , 163–166 (2009).

Hasegawa, K., Namba, Y. & Kimata, Y. Phalloplasty with an innervated island pedicled anterolateral thigh flap in a female-to-male transsexual. Acta Med. Okayama 67 , 325–331 (2013).

PubMed   Google Scholar  

Morrison, S. D. et al . Modification of the tube-in-tube pedicled anterolateral thigh flap for total phalloplasty: the mushroom flap. Ann. Plast. Surg. 72 (Suppl. 1), S22–S26 (2014).

Mutaf, M. A new surgical procedure for phallic reconstruction: Istanbul flap. Plast. Reconstr. Surg. 105 , 1361–1370 (2000).

Hoebeke, P. B. et al . Erectile implants in female-to-male transsexuals: our experience in 129 patients. Eur. Urol. 57 , 334–340 (2010).

Lumen, N. et al . Erectile implants in female-to-male transsexuals: our experience in 130 patients [abstract]. Eur. Urol. Suppl. 7 , 117 (2008).

Neuville, P. et al . Surgical outcomes of erectile implants after phalloplasty: retrospective analysis of 95 procedures. J. Sex. Med. 13 , 1758–1764 (2016). Recent evaluation of outcomes of prosthetics in phalloplasty.

Gurjala, A. N., Nazerali, R. S., Salim, A. & Lee, G. K. World's first baby born through natural insemination by father with total phalloplasty reconstruction. Ann. Plast. Surg. 76 (Suppl. 3), S179–S183 (2016).

Sinove, Y. et al . Preoperative planning of a pedicled anterolateral thigh (ALT) flap for penile reconstruction with the multidetector CT scan. Handchir. Mikrochir. Plast. Chir. 45 , 217–222 (2013).

Liu, C. Y., Wei, Z. R., Jiang, H., Zhao, Y. Z. & Zhang, Y. F. Preconstruction of the pars pendulans urethrae for phalloplasty with digestive mucosa using a prefabricated anterolateral thigh flap in a one-arm patient. Plast. Reconstr. Surg. Glob. Open 1 , e53 (2013).

Rubino, C. et al . Innervated island pedicled anterolateral thigh flap for neo-phallic reconstruction in female-to-male transsexuals. J. Plast. Reconstr. Aesthet. Surg. 62 , e45–e49 (2009).

Chang, T. S. & Hwang, W. Y. Forearm flap in one-stage reconstruction of the penis. Plast. Reconstr. Surg. 74 , 251–258 (1984).

Monstrey, S. et al . Radial Forearm Phalloplasty: a Review of 91 Cases. ANIR-ANHP 6 , 193–199 (2004).

Selvaggi, G. et al . Genital sensitivity after sex reassignment surgery in transsexual patients. Ann. Plast. Surg. 58 , 427–433 (2007). Evaluation of genital sensitivity following phalloplasty for transmen.

Fang, R. H., Kao, Y. S., Ma, S. & Lin, J. T. Phalloplasty in female-to-male transsexuals using free radial osteocutaneous flap: a series of 22 cases. Br. J. Plast. Surg. 52 , 217–222 (1999).

Kim, S. K. et al . The etiology and treatment of the softened phallus after the radial forearm osteocutaneous free flap phalloplasty. Arch. Plast. Surg. 39 , 390–396 (2012).

Trost, L., Wanzek, P. & Bailey, G. A practical overview of considerations for penile prosthesis placement. Nat. Rev. Urol. 13 , 33–46 (2016).

Biemer, E. Penile construction by the radial arm flap. Clin. Plast. Surg. 15 , 425–430 (1988).

Doornaert, M. et al . Penile reconstruction with the radial forearm flap: an update. Handchir. Mikrochir. Plast. Chir. 43 , 208–214 (2011).

Matti, B. A., Matthews, R. N. & Davies, D. M. Phalloplasty using the free radial forearm flap. Br. J. Plast. Surg. 41 , 160–164 (1988).

Salgado, C. J. et al . Immediate pedicled gracilis flap in radial forearm flap phalloplasty for transgender male patients to reduce urinary fistula. J. Plast. Reconstr. Aesthet. Surg. 69 , 1551–1557 (2016).

Selvaggi, G. et al . Donor-site morbidity of the radial forearm free flap after 125 phalloplasties in gender identity disorder. Plast. Reconstr. Surg. 118 , 1171–1177 (2006).

Bardsley, A. F., Soutar, D. S., Elliot, D. & Batchelor, A. G. Reducing morbidity in the radial forearm flap donor site. Plast. Reconstr. Surg. 86 , 287–292 (1990).

Boorman, J. G., Brown, J. A. & Sykes, P. J. Morbidity in the forearm flap donor arm. Br. J. Plast. Surg. 40 , 207–212 (1987).

Richardson, D., Fisher, S. E., Vaughan, E. D. & Brown, J. S. Radial forearm flap donor-site complications and morbidity: a prospective study. Plast. Reconstr. Surg. 99 , 109–115 (1997).

Van Caenegem, E. et al . Long-term evaluation of donor-site morbidity after radial forearm flap phalloplasty for transsexual men. J. Sex. Med. 10 , 1644–1651 (2013).

Rieger, U. M. et al . Comparative study of the free microvascular groin flap: optimizing the donor site after free radial forearm flap phalloplasty. Urology 95 , 192–196 (2016).

Fang, R. H., Lin, J. T. & Ma, S. Phalloplasty for female transsexuals with sensate free forearm flap. Microsurgery 15 , 349–352 (1994).

Gottlieb, L. J. & Levine, L. A. A new design for the radial forearm free-flap phallic construction. Plast. Reconstr. Surg. 92 , 276–283 (1993).

Hage, J. J., Bouman, F. G., de Graaf, F. H. & Bloem, J. J. Construction of the neophallus in female-to-male transsexuals: the Amsterdam experience. J. Urol. 149 , 1463–1468 (1993).

Kim, S. K., Lee, K. C., Kwon, Y. S. & Cha, B. H. Phalloplasty using radial forearm osteocutaneous free flaps in female-to-male transsexuals. J. Plast. Reconstr. Aesthet. Surg. 62 , 309–317 (2009).

Koshima, I., Tai, T. & Yamasaki, M. One-stage reconstruction of the penis using an innervated radial forearm osteocutaneous flap. J. Reconstr. Microsurg. 3 , 19–26 (1986).

Leriche, A. et al . Long-term outcome of forearm flee-flap phalloplasty in the treatment of transsexualism. BJU Int. 101 , 1297–1300 (2008).

Ma, S., Cheng, K. & Liu, Y. Sensibility following innervated free radial forearm flap for penile reconstruction. Plast. Reconstr. Surg. 127 , 235–241 (2011).

Ma, S., Liu, Y., Chang, T. & Cheng, K. Long-term follow-up of sensation recovery of the penis reconstructed by Cheng's method. Plast. Reconstr. Surg. 127 , 1546–1552 (2011).

Papadopulos, N. A., Schaff, J. & Biemer, E. Usefulness of free sensate osteofasciocutaneous forearm and fibula flaps for neophallus construction. J. Reconstr. Microsurg. 17 , 407–412 (2001).

Sasaki, K., Nozaki, M., Morioka, K. & Huang, T. T. Penile reconstruction: combined use of an innervated forearm osteocutaneous flap and big toe pulp. Plast. Reconstr. Surg. 104 , 1054–1058 (1999).

Song, C., Wong, M., Wong, C. H. & Ong, Y. S. Modifications of the radial forearm flap phalloplasty for female-to-male gender reassignment. J. Reconstr. Microsurg. 27 , 115–120 (2011).

Vriens, J. P., Acosta, R., Soutar, D. S. & Webster, M. H. Recovery of sensation in the radial forearm free flap in oral reconstruction. Plast. Reconstr. Surg. 98 , 649–656 (1996).

Waits, C. A., Toby, E. B., Girod, D. A. & Tsue, T. T. Osteocutaneous radial forearm free flap: long-term radiographic evaluation of donor site morbidity after prophylactic plating of radius. J. Reconstr. Microsurg. 23 , 367–372 (2007).

Ma, S., Cheng, K., Liu, Y. & Chen, F. A new surgical procedure for penile reconstruction by combined free radial forearm flap and dorsalis pedis flap. Urology 97 , 232–237 (2016).

Hoebeke, P., de Cuypere, G., Ceulemans, P. & Monstrey, S. Obtaining rigidity in total phalloplasty: experience with 35 patients. J. Urol. 169 , 221–223 (2003).

Selvaggi, G. et al . Scrotal reconstruction in female-to-male transsexuals: a novel scrotoplasty. Plast. Reconstr. Surg. 123 , 1710–1718 (2009). Presentation of the novel technique for transman scrotoplasty.

Hage, J. J., Bouman, F. G. & Bloem, J. J. Constructing a scrotum in female-to-male transsexuals. Plast. Reconstr. Surg. 91 , 914–921 (1993).

Millard, D. R. Jr. Scrotal construction and reconstruction. Plast. Reconstr. Surg. 38 , 10–15 (1966).

Reid, C. F. & Wright, J. H. Jr. Scrotal reconstruction following an avulsion injury. J. Urol. 133 , 681–682 (1985).

Sengezer, M. & Sadove, R. C. Scrotal construction by expansion of labia majora in biological female transsexuals. Ann. Plast. Surg. 31 , 372–376 (1993).

Still, E. F. II & Goodman, R. C. Total reconstruction of a two-compartment scrotum by tissue expansion. Plast. Reconstr. Surg. 85 , 805–807 (1990).

Lumen, N., Monstrey, S., Goessaert, A. S., Oosterlinck, W. & Hoebeke, P. Urethroplasty for strictures after phallic reconstruction: a single-institution experience. Eur. Urol. 60 , 150–158 (2011). Analysis of outcomes and techniques for urethral fistula and stricture repair in phalloplasty.

Wilson, S. C. et al . Fasciocutaneous flap reinforcement of ventral onlay buccal mucosa grafts enables neophallus revision urethroplasty. Ther. Adv. Urol. 8 , 331–337 (2016).

Dabernig, J., Shelley, O. P., Cuccia, G. & Schaff, J. Urethral reconstruction using the radial forearm free flap: experience in oncologic cases and gender reassignment. Eur. Urol. 52 , 547–553 (2007).

Garaffa, G., Ralph, D. J. & Christopher, N. Total urethral construction with the radial artery-based forearm free flap in the transsexual. BJU Int. 106 , 1206–1210 (2010).

Kim, S. K., Moon, J. B., Heo, J., Kwon, Y. S. & Lee, K. C. A new method of urethroplasty for prevention of fistula in female-to-male gender reassignment surgery. Ann. Plast. Surg. 64 , 759–764 (2010).

Bayramicli, M. & Akdeniz, Z. D. Urethra reconstruction with lateral pectoral flap in female-to-male transsexual patients. J. Plast. Reconstr. Aesthet. Surg. 69 , 1558–1560 (2016).

De Filippo, R. E., Yoo, J. J. & Atala, A. Urethral replacement using cell seeded tubularized collagen matrices. J. Urol. 168 , 1789–1792 (2002).

Chen, K. L., Eberli, D., Yoo, J. J. & Atala, A. Bioengineered corporal tissue for structural and functional restoration of the penis. Proc. Natl Acad. Sci. USA 107 , 3346–3350 (2010).

Joo, K. J. et al . Porcine vesical acellular matrix graft of tunica albuginea for penile reconstruction. Asian J. Androl. 8 , 543–548 (2006).

Kwon, T. G., Yoo, J. J. & Atala, A. Autologous penile corpora cavernosa replacement using tissue engineering techniques. J. Urol. 168 , 1754–1758 (2002).

Kropp, B. P. et al . Use of small intestinal submucosa for corporal body grafting in cases of severe penile curvature. J. Urol. 168 , 1742–1745 (2002).

Raya-Rivera, A. M. et al . Tissue-engineered autologous vaginal organs in patients: a pilot cohort study. Lancet 384 , 329–336 (2014).

Sopko, N. A. et al . Ex vivo model of human penile transplantation and rejection: implications for erectile tissue physiology. Eur. Urol. 71 , 584–593 (2017).

Tuffaha, S. H. et al . Using the dorsal, cavernosal, and external pudendal arteries for penile transplantation: technical considerations and perfusion territories. Plast. Reconstr. Surg. 134 , 111e–119e (2014).

Selvaggi, G., Branemark, R., Elander, A., Liden, M. & Stalfors, J. Titanium-bone-anchored penile epithesis: preoperative planning and immediate postoperative results. J. Plast. Surg. Hand. Surg. 49 , 40–44 (2015).

Selvaggi, G., Elander, A. & Branemark, R. Penile epithesis: preliminary study. Plast. Reconstr. Surg. 126 , 265e–266e (2010).

Massie, J. P., Morrison, S. D., Smith, J. R., Wilson, S. C. & Satterwhite, T. Letter to the editor regarding “Surgical outcome after penile inversion vaginoplasty: a retrospective study of 475 transgender women” by Buncamper et al . Plast. Reconstr. Surg. http://dx.doi.org/10.1097/PRS.0000000000003479 (2017).

Berli, J. U. et al . What surgeons need to know about gender confirmation surgery when providing care for transgender individuals: a review. JAMA Surg. 152 , 394–400 (2017).

Download references

Author information

Authors and affiliations.

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, 98195, WA, USA

Shane D. Morrison

Brownstein & Crane Surgical Services, 575 Sir Francis Drake Blvd, Ste 1, Greenbrae, 94904, CA, USA

Mang L. Chen & Curtis N. Crane

You can also search for this author in PubMed   Google Scholar

Contributions

S.D.M., C.N.C and M.C. researched data for article, made substantial contributions to discussions of content, and reviewed and edited the manuscript before submission. S.D.M. and M.C. wrote the article.

Corresponding author

Correspondence to Curtis N. Crane .

Ethics declarations

Competing interests.

The authors declare no competing financial interests.

PowerPoint slides

Powerpoint slide for fig. 1, powerpoint slide for fig. 2, powerpoint slide for fig. 3, powerpoint slide for fig. 4, powerpoint slide for fig. 5, powerpoint slide for fig. 6, powerpoint slide for fig. 7, powerpoint slide for table 1.

Inherent discordance of a patient's gender expression and their anatomy leading to distress

Tissue forming the nipple and surrounding areola on the breast or chest

A physical examination test to determine the patency of the palmar or plantar arches as a correlate for the dominant inflow vessel to the hand or foot. Most commonly it is used in the hand where the radial and ulnar arteries are both occluded with pressure from the examiners hand and each is released sequentially while maintaining the pressure on the other artery. The perfusion of the hand is monitored to ensure both vessels can perfuse the hand.

A person born as a male and whose gender identity is male.

Urological procedure for urethral strictures, in which the ventral aspect of the phallus is opened through the urethra. The urethra is secured to the skin and urine is diverted. A second stage completed months later is used to repair the urethra with grafted tissue over a catheter.

Flaps containing multiple tissue types (skin, bone, mucosa.) based on a single angiosome used for complex reconstruction.

Local flap used for advancing tissue generally to cover a wound, but can be used in other procedures. An incision shaped like a V is made through the subcutaneous tissue, advanced into its new position relying on subcutaneous perfusion, and closed in a Y pattern.

Closure of a urethral stricture with a longitudinal incision followed by a transverse closure.

A person born with female sexual organs, but whose gender identity is male

Rights and permissions

Reprints and permissions

About this article

Cite this article.

Morrison, S., Chen, M. & Crane, C. An overview of female-to-male gender-confirming surgery. Nat Rev Urol 14 , 486–500 (2017). https://doi.org/10.1038/nrurol.2017.64

Download citation

Published : 16 May 2017

Issue Date : August 2017

DOI : https://doi.org/10.1038/nrurol.2017.64

Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

This article is cited by

Geschlechtsinkongruenz – definition, diagnosestellung und transitionsoptionen.

  • Antje Feicke
  • Barbara Mijuskovic

Urologie in der Praxis (2023)

(De-)centralized health care delivery, surgical outcome, and psychosocial health of transgender and gender-diverse people undergoing vaginoplasty: results of a retrospective, single-center study

  • Andreas Koehler
  • Bernhard Strauß
  • Timo O. Nieder

World Journal of Urology (2023)

Gender Affirmation Surgery for the Transmasculine Patient

  • Michael Callegari
  • Gaetan Pettigrew
  • Shubham Gupta

Current Obstetrics and Gynecology Reports (2022)

Urethral complications after gender reassignment surgery: a systematic review

  • L. R. Doumanian

International Journal of Impotence Research (2021)

Suprapubic phalloplasty in transmen: surgical results and critical review

  • Manon Terrier
  • Nicolas Morel-Journel
  • Paul Neuville

Quick links

  • Explore articles by subject
  • Guide to authors
  • Editorial policies

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

how do they do gender reassignment surgery male to female

Medindia

Medindia » Articles » Procedure » Gender-Reassignment Surgery: Everything You Need to Know

Gender-Reassignment Surgery: Everything You Need to Know

  • Indications

Non-Surgical Procedures

  • Surgical Procedures

Risks in Non-Surgical and Surgical Procedures

  • Whom to consult?
  • Pre-Op Considerations
  • Post-Op Considerations

Impact on Mental Health

  • Cost of the Surgery

Gender reassignment surgery, also known as gender-affirming surgery, is a medical procedure or series of procedures aimed at altering an individual's physical appearance and sexual characteristics to align with their gender identity.

In Simple words, it can be defined as the alteration of a person's physical sex characteristics by surgery in order to match the person’s gender identity

This transformative process is often pursued by transgender individuals, as well as some cisgender and non-binary individuals. It involves various surgical interventions to modify primary and secondary sexual characteristics, thereby affirming an individual's gender identity( 1 ✔ ✔ Trusted Source Sex Reassignment Surgery in the Female-to-Male Transsexual Go to source ).

Alternative Names for Gender-Affirming Surgery

  • Gender reassignment surgery (GRS)
  • Gender-affirmation surgery
  • Gender confirmation surgery
  • Sex reassignment surgery

Who Can Get Gender Reassignment Surgery?

Transgender individuals.

Transgender individuals are those whose gender identity differs from the sex they were assigned at birth. Many transgender individuals experience gender dysphoria, a condition characterized by distress or discomfort caused by a misalignment between their gender identity and physical body. Gender reassignment surgery is often sought by transgender individuals as part of their transition journey to alleviate gender dysphoria and align their physical appearance with their gender identity.

Trans Women: Assigned male at birth but identify and live as women. Trans women may pursue feminizing surgeries such as vaginoplasty (creation of a vagina), breast augmentation, facial feminization surgery, and voice feminization surgery to affirm their gender identity.

Trans Men: Assigned female at birth but identify and live as men. Trans men may undergo masculinizing surgeries such as chest reconstruction (removal of breast tissue), hysterectomy (removal of the uterus), and phalloplasty or metoidioplasty (creation of a penis) to align their bodies with their gender identity.

Intersex Individuals

Intersex is a term used to describe individuals who are born with variations in their biological sex characteristics (chromosomes, gonads (testes/ovaries), reproductive organs (prostate/uterus) or external genitalia (penis/clitoris)) that do not fit typical definitions of male or female.

Intersex Individuals with Gender Dysphoria: While intersex individuals can be transgender if their gender identity does not match the sex they were raised or assigned as, some intersex individuals may experience distress or discomfort, known as gender dysphoria , due to a misalignment between their gender identity and assigned sex characteristics, and seek gender-affirming surgery to align their physical appearance with their gender identity( 2 ✔ ✔ Trusted Source Gender Affirmation Surgeries Go to source ).

Drag Performers

Drag performers are individuals who utilize clothing, makeup, and performance art to explore and celebrate gender expression. They are typically associated with a gender different from their own. These performers engage in drag for various reasons, including self-expression, artistic exploration, and entertainment purposes.

While some drag performers may identify as transgender or non-binary and use drag as a form of self-expression or exploration of their gender identity, others may identify as cisgender and engage in drag purely for entertainment or artistic expression.

Drag Queens and Drag Kings : Drag queens are typically male individuals who dress in feminine attire and adopt exaggerated female personas for performance. Drag kings, on the other hand, present as male or masculine while performing. While some drag performers may identify as transgender and may ultimately pursue gender-affirming surgeries, the act of performing drag does not inherently imply a desire for surgical intervention.

Individuals with Klinefelter Syndrome

Klinefelter syndrome is a chromosomal condition in which individuals are born with an extra X chromosome (XXY), resulting in differences in sexual development and often leading to infertility and other physical characteristics such as tall stature, reduced muscle mass, and gynecomastia (enlarged breast tissue in males)( 4 ✔ ✔ Trusted Source Klinefelter syndrome Go to source ).

While not directly related to transgender identity, some individuals with Klinefelter syndrome may experience gender dysphoria and seek gender-affirming treatments, including surgery. These individuals may undergo procedures to modify their physical characteristics to better align with their gender identity and alleviate distress associated with gender dysphoria.

Non-Binary Individuals

"Non-binary" is a term used to describe individuals whose gender identity does not exclusively align with the categories of male or female. This is a deeply personal and internal sense of one's own gender. Non-binary individuals may identify as both, neither, a combination of both, or as a gender entirely different from male or female.

Bigenital Operation: Bigenital operations allow individuals to construct a penis or vagina and retain their original organs. Some non-binary individuals may opt for these surgeries to achieve a physical presentation that aligns with their gender identity while maintaining aspects of their original anatomy. These surgeries cater to the diverse spectrum of gender identities and expressions and provide options for individuals who do not fit within the traditional binary understanding of gender.

"Cisgender" is a term used to describe individuals whose gender identity aligns with the sex they were assigned at birth. In other words, someone who is cisgender identifies as the gender typically associated with the biological sex they were born with. For example, a person who was assigned female at birth and identifies as a woman is considered cisgender. The term "cisgender" is often used in contrast to "transgender," which describes individuals whose gender identity differs from the sex they were assigned at birth

While gender dysphoria is often associated with transgender individuals, cisgender people can also experience it. In some cases, cisgender individuals with severe gender dysphoria may seek gender-affirming surgeries to alleviate their distress and bring their physical appearance into alignment with their gender identity. These surgeries are typically pursued after extensive evaluation and therapy, and they can significantly improve the mental health and well-being of individuals experiencing gender dysphoria.

Is Gender Dysphoria the only Reason for Gender Reassignment Surgery?

No, not only gender dysphoric individuals seek gender reassignment surgery. While gender dysphoria is a common reason why individuals pursue gender-affirming surgeries, it's not the only factor. Some people may choose to undergo these surgeries for reasons beyond alleviating distress associated with gender dysphoria.

For example, individuals with intersex variations may seek gender-affirming surgeries to align their physical appearance with their gender identity, even if they do not experience gender dysphoria. Similarly, some non-binary individuals may opt for surgeries to achieve a physical presentation that better aligns with their gender identity, regardless of whether they experience gender dysphoria.

Furthermore, some cisgender individuals may also undergo gender-affirming surgeries for reasons related to body dysmorphia or dissatisfaction with their physical appearance, rather than gender dysphoria.

Ultimately, the decision to pursue gender reassignment surgery is deeply personal and can be influenced by a variety of factors beyond gender dysphoria alone.

Hormonal injections is the only available non-surgical procedure.It isa form of hormone replacement therapy (HRT) commonly used in transgender healthcare to induce and maintain desired physical changes consistent with an individual's gender identity.

These injections typically involve the administration of testosterone for transmasculine individuals (female-to-male, or FtM) and estrogen for transfeminine individuals (male-to-female, or MtF).

Testosterone Injections (for Transmasculine Individuals)

Purpose : Testosterone injections are administered to induce masculine changes, such as increased facial and body hair growth, deepening of the voice, muscle development, and redistribution of body fat.

Types of Testosterone : There are different formulations of testosterone available for injection, including testosterone cypionate, testosterone enanthate, and testosterone undecanoate.

Administration : Testosterone injections are typically administered intramuscularly (into the muscle) in either the gluteal (buttocks) or deltoid (upper arm) muscle.

Dosage and Frequency : The dosage and frequency of testosterone injections can vary depending on individual factors such as age, weight, hormone levels, and desired changes. Typically, injections are administered every one to two weeks to maintain stable testosterone levels in the body.

Monitoring : Regular monitoring of hormone levels, liver function, and other relevant markers is essential to ensure the safety and effectiveness of testosterone therapy. Blood tests may be conducted periodically to assess hormone levels and adjust the dosage as needed.

Estrogen Injections (for Transfeminine Individuals)

Purpose : Estrogen injections are administered to induce feminine changes, such as breastdevelopment, redistribution of body fat, softening of the skin, and reduction of muscle mass.

Types of Estrogen : The most common form of estrogen used in injections is estradiol valerate.

Administration : Estrogen injections are typically administered intramuscularly, similar to testosterone injections, in the gluteal or deltoid muscle.

Dosage and Frequency : The dosage and frequency of estrogen injections vary depending on individual factors and treatment goals. Typically, injections are administered every one to two weeks.

Monitoring : Regular monitoring of hormone levels, liver function, and other relevant parameters is crucial for ensuring the safety and effectiveness of estrogen therapy. Blood tests may be conducted periodically to assess hormone levels and adjust the dosage as needed.

Time Frame of Use of Hormonal Injections

Initiation : Hormonal injections are often initiated after a thorough evaluation by healthcare providers, including discussions about treatment goals, potential risks and benefits, and informed consent. The timing of initiation may vary depending on individual factors such as age, readiness for treatment, and presence of any underlying health conditions.

Duration : Hormonal injections are typically used as part of long-term hormone replacement therapy to maintain desired physical changes and support overall well-being. The duration of hormone therapy may vary from individual to individual and often continues indefinitely, especially for those who desire ongoing maintenance of gender-affirming changes.

Discontinuation : In some cases, individuals may choose to discontinue hormonal injections for various reasons, such as personal preference, changes in health status, or the achievement of desired physical changes. It's essential for individuals to discuss any plans to discontinue hormone therapy with their healthcare provider to ensure proper management of any potential effects or complications.

Surgical Procedures: Gender Affirming Surgery

These surgical procedures play vital roles in gender affirmation for transgender individuals, aligning their physical appearance with their gender identity( 3 ✔ ✔ Trusted Source Gender Confirmation Surgery Go to source ).

Male-to-Female (MtF) Transitions:

  • Tracheal Shave: This procedure reduces the prominence of the Adam's apple, a typically male characteristic, to create a smoother, more feminine neck contour.
  • Breast Augmentation: Transfeminine individuals undergo breast augmentation to develop fuller, more feminine breast contours. Breast implants are placed behind breast tissue or chest muscle to achieve the desired size and shape.
  • Facial Feminization Surgery (FFS): FFS encompasses various surgical procedures aimed at feminizing facial features. Techniques may include forehead contouring, rhinoplasty , cheek augmentation, chin and jaw reshaping, tracheal shave, lip augmentation, and hairline lowering to achieve a more traditionally feminine appearance.
  • Male-to-Female Genital Sex Reassignment (Vaginoplasty): This surgical procedure constructs female genitalia for transfeminine individuals seeking alignment with their gender identity. Techniques involve using penile and scrotal tissue to create the vaginal canal, labia, and clitoral hood. The procedure may also include the creation of a neurovascular neoclitoris, providing both aesthetic and functional female genitalia in one operation.

Female-to-Male (FtM) Transitions:

  • Hysterectomy and Oophorectomy: This procedure involves the removal of the uterus and ovaries, reducing the production of female hormones (estrogen and progesterone).
  • Vaginectomy: Vaginectomy is the surgical removal of the vaginal canal, aligning the physical anatomy with a masculine appearance.
  • Chest Reconstruction (Top Surgery): FtM individuals undergo chest reconstruction surgery to remove breast tissue and reshape the chest to achieve a more masculine contour. Techniques include subcutaneous mastectomy or double mastectomy with or without nipple reconstruction.
  • Female-to-Male Genital Sex Reassignment (Phalloplasty): Phalloplasty is a surgical procedure to construct a phallus for FtM individuals seeking male genitalia. The radial forearm flap method is commonly used, involving tissue grafting from the forearm to create the phallus and urethra for standing urination. This procedure can be performed concurrently with a hysterectomy/vaginectomy to complete the transition process. A scrotum with testicular implants may be constructed in a second stage.

These surgical interventions are integral to gender affirmation for transgender individuals, helping align their physical appearance with their gender identity and alleviating gender dysphoria. Each procedure is tailored to the individual's unique needs and goals, reflecting the diversity of experiences within the transgender community.

Treatment of Gender-Reassignment Surgery

Risks in Hormone Therapies

  • Cardiovascular Risks : Hormone replacement therapy (HRT) may increase the risk of cardiovascular events such as heart attacks and strokes, especially in older individuals or those with pre-existing cardiovascular conditions.
  • Thromboembolic Events : Estrogen therapy, particularly in forms like oral contraceptives, may elevate the risk of blood clots, leading to thromboembolic events such as deep vein thrombosis (DVT) or pulmonary embolism (PE).
  • Endocrine Disruption : Hormone therapies can disrupt the body's natural hormone balance, leading to potential complications such as metabolic disturbances, including insulin resistance and dyslipidemia.
  • Breast Cancer Risk : Some studies suggest that long-term use of hormone replacement therapy, especially estrogen-only formulations, may increase the risk of breast cancer in transgender women.
  • Liver Dysfunction : Hormone therapies, particularly oral estrogen formulations, may affect liver function and increase the risk of liver disease or dysfunction.

Risks in Gender Reassignment Surgeries

  • Surgical Complications : As with any surgical procedure, gender reassignment surgeries carry risks such as infection, bleeding , anesthesia complications, and adverse reactions to medications.
  • Scarring : Gender-affirming surgeries, especially those involving breast augmentation, chest reconstruction, or genital reconstruction, may result in visible scarring that could impact body image and self-esteem.
  • Loss of Sensation : Surgeries involving genital reconstruction, such as vaginoplasty or phalloplasty, may result in loss of sensation or altered sensation in the genital region, affecting sexual function and satisfaction.
  • Functional Complications : Some individuals may experience functional complications post-surgery, such as urinary incontinence , erectile dysfunction, or difficulties with sexual arousal or orgasm.
  • Psychological Impact : Gender reassignment surgeries can have profound psychological effects, including adjustment difficulties, post-operative depression, and challenges related to body image and identity.

Guidance on Surgical Procedures: Whom to Consult?

When contemplating gender reassignment surgery, it's essential for individuals to consult with a team of experienced healthcare providers specializing in transgender care. Here's whom to consider consulting:

1. Gender-Affirming Surgeons

Gender-affirming surgeons specialize in performing gender reassignment surgeries and have expertise in various surgical techniques, including chest surgery (for both masculinization and feminization procedures), genital reconstruction, and facial feminization surgery. These surgeons can provide comprehensive information about the surgical options available, discuss the potential risks and benefits, and guide individuals through the decision-making process.

2. Endocrinologists

Endocrinologists play a crucial role in managing hormone therapy for transgender individuals. They can provide guidance on hormone replacement therapy (HRT), including the use of testosterone for transmasculine individuals and estrogen for transfeminine individuals. Endocrinologists can assess hormone levels, monitor any potential side effects, and adjust hormone regimens as needed to support the transition process.

3. Mental Health Professionals

Mental health professionals, such as psychologists, psychiatrists, or licensed therapists, offer invaluable support throughout the gender transition journey. They can assist individuals in exploring their gender identity, coping with gender dysphoria, and addressing any psychological concerns or challenges that may arise before, during, or after surgery. Mental health professionals also play a role in assessing readiness for surgery and providing pre- and post-operative counseling and support.

4. Primary Care Physicians

Primary care physicians are essential members of the healthcare team and can provide general medical care, coordinate referrals to specialists, and monitor overall health and well-being. They can also assist with managing any pre-existing medical conditions and ensuring that individuals are physically fit for surgery.

5. Support Groups and Advocacy Organizations

Support groups and advocacy organizations within the transgender community can offer valuable peer support, resources, and information about gender-affirming surgeries. These groups provide opportunities for individuals to connect with others who have undergone similar experiences, share insights, and seek guidance from those who have navigated the transition process.

Consulting with a multidisciplinary team of healthcare providers ensures that individuals receive comprehensive care tailored to their unique needs and goals. This collaborative approach helps individuals make informed decisions about gender reassignment surgery and supports their overall health and well-being throughout the transition process.

Pre-operative Considerations

1. Medical Considerations

Transgender individuals may have preexisting health conditions like diabetes , asthma , or HIV, which can impact their eligibility for surgery and postoperative care. Surgeons often consult with endocrinologists to assess the patient's physical fitness for surgery, especially considering the complex medication regimens involved in hormone therapy before and after surgery.

2. Fertility Concerns

Patients considering sex reassignment surgery (SRS) are informed about potential infertility, particularly if procedures like orchiectomy or oophorectomy are performed as part of the transition process. Preservation of fertility options may be discussed before surgery.

3. Age and Consent

SRS is generally not performed on children under 18, with rare exceptions made for adolescents based on healthcare provider assessments and potential benefits or risks. Consent from parents or legal guardians is required, along with long-term mental health counseling to confirm persistent gender dysphoria.

4. Intersex and Trauma Cases

Infants born with intersex traits may undergo surgical interventions at or near birth, raising ethical concerns about human rights implications. Trauma cases also require careful consideration, as surgically assigned gender may not align with the individual's gender identity, leading to negative outcomes later in life.

5. Standards of Care

Many regions follow Standards of Care for the Health of Transgender and Gender Diverse People (SOC), such as those published by the World Professional Association for Transgender Health (WPATH). These guidelines outline minimum requirements for treatment, including psychological evaluation and living as the desired gender before surgery.

6. Insurance Coverage

Obtaining insurance coverage for SRS may require documented assessments by mental health professionals, evidence of persistent gender dysphoria, and completion of physician-supervised hormone therapy for a specified duration.

Post-operative Considerations

1. Quality of Life and Physical Health

Studies assessing postoperative quality of life vary, with some reporting similar quality to control groups while others note lower quality in domains of health and limitations. Overall, many individuals report improvements in mental health, satisfaction with physical appearance, and overall well-being after surgery.

2. Psychological and Social Consequences

SRS has been shown to be effective in relieving gender dysphoria, though some studies highlight methodological limitations. Patients often report reduced anxiety, depression , and hostility levels post-surgery, with improvements in self-perceived physical and mental health.

3. Sexuality and Sexual Satisfaction

SRS can significantly impact individuals' sexual experiences and satisfaction. Most transsexual individuals report enjoying better sex lives and improved sexual satisfaction after surgery, with changes in orgasm frequency, intensity, and masturbation habits observed. However, satisfaction levels may vary between trans men and trans women, and expectations for sexual aspects of life may differ from cisgender individuals.

4. Continued Support

Comprehensive postoperative care involves ongoing psychological support, management of any complications, and assistance with adjustment to physical changes. Social support networks play a crucial role in helping individuals navigate their post-surgical experiences and integrate their gender identities into their daily lives.

The denial or limited access to gender-affirming surgeries can have severe consequences for the mental health and well-being of transgender individuals.

1. Persistent Gender Dysphoria

Without access to surgery, transgender individuals may continue to experience intense distress and discomfort due to the misalignment between their gender identity and physical characteristics. This persistent gender dysphoria can lead to heightened anxiety, depression, and a sense of hopelessness.

2. Heightened Anxiety

Living in a body that does not align with one's gender identity can contribute to persistent anxiety. The frustration of being unable to access necessary medical care and the ongoing struggle to navigate societal expectations can exacerbate feelings of stress and worry.

3. Increased Depression

Untreated gender dysphoria and the inability to undergo gender-affirming surgeries can lead to deepening feelings of depression and despair. Transgender individuals may struggle with low self-esteem, feelings of worthlessness, and a sense of isolation from not being able to live authentically.

4. Social Withdrawal

The distress caused by the incongruence between one's gender identity and physical appearance can result in social withdrawal and avoidance of social interactions. Transgender individuals may feel ashamed or uncomfortable in social settings, leading to further isolation and loneliness.

5. Suicidal Ideation

The lack of access to gender-affirming surgeries and the ongoing struggle with gender dysphoria can significantly increase the risk of suicidal thoughts and behaviors. Without the hope of being able to live authentically and alleviate their distress, transgender individuals may experience profound feelings of hopelessness and desperation.

Click here to know more about Mental health in transgender community

Affordable Surgery Options

Gender-affirming surgeries, including gender reassignment surgery (GRS), vary widely in cost globally. Affordable options exist in countries like Turkey, Brazil, Argentina, and Belgium. Turkey offers the most budget-friendly option, followed by Brazil, Argentina, and Belgium. While these countries provide competitive prices, individuals should consider factors beyond cost, such as healthcare quality and legal protections.

Click here for detailed information on the global cost of these surgeries and to find out which options are more affordable

In summary, gender reassignment surgery serves as a vital tool in validating the gender identities of transgender and intersex individuals, enabling them to harmonize their external appearance with their innate sense of self. Despite its transformative potential, many face obstacles in accessing this essential care, including financial constraints, inadequate insurance coverage, and legal hurdles.

As society progresses towards greater awareness and acceptance of transgender rights, it's imperative to prioritize equitable access to gender-affirming treatments and offer unwavering support to individuals throughout their transition journey. By dismantling these barriers and fostering inclusivity within healthcare systems, we can empower transgender individuals to live authentically and flourish in their gender identity.

Html.Raw(Model.contents.ToString())

  • Sex Reassignment Surgery in the Female-to-Male Transsexual - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312187/)
  • Gender Affirmation Surgeries - (https://www.hopkinsmedicine.org/health/wellness-and-prevention/gender-affirmation-surgeries)
  • Gender Confirmation Surgery - (https://www.uofmhealth.org/conditions-treatments/transgender-services/gender-confirmation-surgery)
  • Klinefelter syndrome - (https://www.nhs.uk/conditions/klinefelters-syndrome/)

Please use one of the following formats to cite this article in your essay, paper or report:

Dr. Preethi Balasubramanian. (2024, May 08). Gender-Reassignment Surgery: Everything You Need to Know . Medindia. Retrieved on May 10, 2024 from https://www.medindia.net/health/procedure/gender-reassignment-surgery-everything-you-need-to-know.htm.

Dr. Preethi Balasubramanian. "Gender-Reassignment Surgery: Everything You Need to Know". Medindia . May 10, 2024. <https://www.medindia.net/health/procedure/gender-reassignment-surgery-everything-you-need-to-know.htm>.

Dr. Preethi Balasubramanian. "Gender-Reassignment Surgery: Everything You Need to Know". Medindia. https://www.medindia.net/health/procedure/gender-reassignment-surgery-everything-you-need-to-know.htm. (accessed May 10, 2024).

Dr. Preethi Balasubramanian. 2024. Gender-Reassignment Surgery: Everything You Need to Know . Medindia, viewed May 10, 2024, https://www.medindia.net/health/procedure/gender-reassignment-surgery-everything-you-need-to-know.htm.

  • Neuroscience for Kids - (http://faculty.washington.edu/chudler/words.html)
  • What the Stroop Effect Reveals About Our Minds - (https://lesley.edu/article/what-the-stroop-effect-reveals-about-our-minds)
  • The Emotional Stroop Effect Is Modulated by the Biological Salience and Motivational Intensity Inherent in Stimuli - (https://www.frontiersin.org/articles/10.3389/fpsyg.2019.03023/full)
  • Numerical stroop effect - (https://pubmed.ncbi.nlm.nih.gov/15058867/)
  • The Emotional Stroop Task: Assessing Cognitive Performance under Exposure to Emotional Content - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4993290/)
  • The Stroop Effect - (https://www.simplypsychology.org/stroop-effect.html)
  • Ask an Expert: How does Stroop Effect apply to real life situations? - (https://www.sciencebuddies.org/science-fair-projects/ask-an-expert/viewtopic.php?t=6139)
  • Stroop Effect - (https://conductscience.com/portfolio/stroop-effect/#:~:text=Stroop%20effect%20has%20many%20practical,bipolar%20disorder%2C%20or%20major%20depression.)
  • Stroop Test - (https://www.sciencedirect.com/topics/psychology/stroop-test)
  • Clinical Application of the Modified Stroop Test to Children with Attention Deficit/Hyperactivity Disorder - (https://www.researchgate.net/publication/47792734_Clinical_Application_of_the_Modified_Stroop_Test_to_Children_with_Attention_DeficitHyperactivity_Disorder)

Anita Ramesh. (2021, September 17). Stroop Effect . Medindia. Retrieved on Apr 21, 2023 from https://www.medindia.net/patients/lifestyleandwellness/stroop-effect.htm.

Anita Ramesh. "Stroop Effect". Medindia . Apr 21, 2023. <https://www.medindia.net/patients/lifestyleandwellness/stroop-effect.htm>.

Anita Ramesh. "Stroop Effect". Medindia. https://www.medindia.net/patients/lifestyleandwellness/stroop-effect.htm. (accessed Apr 21, 2023).

Anita Ramesh. 2021. Stroop Effect . Medindia, viewed Apr 21, 2023, https://www.medindia.net/patients/lifestyleandwellness/stroop-effect.htm.

Transgender Hormone Therapy Tied to Blood Pressure Risk

ASK A DOCTOR ONLINE

Get Health and Wellness Secrets from Our Engaging eBooks

What's New on Medindia

Test Your Knowledge On Cell Free DNA

Follow @MedIndia

Available on the Android Market

Gender-Reassignment Surgery: Everything You Need to Know - Related News

  • Addressing Mental Health Needs in the Transgender Community
  • A Global Comparison: Best Countries for Gender Reassignment Surgery
  • Transgender Healthcare Disparities Highlighted
  • Why is Thyroid Cancer More Common Among Transgender Female Veterans?
  • Is Gender Reassignment Surgery Against Nature?
  • Consult Online Doctor
  • Take Telemedicine course
  • Health Centers
  • Health Tools
  • Health info by Speciality
  • Know Your Body
  • Health and Wellness
  • Web Stories
  • Health Tips
  • Nutrition Facts
  • Lifestyle & Wellness
  • Beauty Tips
  • Diet & Nutrition
  • Home Remedies
  • Obesity & Weight Loss
  • Complementary Medicine
  • Special Reports
  • Press Releases
  • Health Guide
  • Health articles
  • Health Quiz
  • Health Facts
  • Travel Health
  • Medicine and Movies
  • Symptom Articles
  • Diabetes Tools
  • Pediatric Calculators
  • Men's Health
  • Women's Health
  • Height Weight Tools
  • Cardiac Tools
  • Pharma Tools
  • Wellness Interactive Tools
  • Drug Information
  • Drugs by Condition
  • Drug Price List - Brand Names
  • Drug Interaction with Food
  • Drug Price List - Generic Names
  • Drugs - Side Effects
  • Drug Videos
  • Drug Database
  • Doctor Directory
  • Diagnostic Lab Directory
  • Hospital Directory
  • Pharmacy or Chemist
  • Medical Equipment Suppliers
  • Pharma Directory
  • Emergency Services
  • PG Education
  • Family Medicine
  • Other Resources
  • Medical Aphorism
  • Health Acts in India
  • Health Quotations
  • Medical Conference
  • Amazing Body Facts
  • Health poll

open

  • Editorial Team
  • Exclusive Interviews
  • In the News
  • Partners & Affiliates
  • Advertise With Us
  • हिन्दी
  • français
  • Español
  • 中文

StarTribune

Ethics panel takes up complaint against republican senator who sent graphic video link.

An ethics panel Tuesday delayed action for yet another day on the question of whether Sen. Glenn Gruenhagen violated the norms of the state Senate by sending to his 66 colleagues a link to a video about gender-affirming surgery.

Sen. Erin Maye Quade, DFL-Apple Valley, filed the complaint against the Glencoe Republican in April 2023, but the Senate's ethics subcommittee didn't take it up until now. The four-person panel agreed to think about it and come back at 3 p.m. Wednesday to decide what, if anything, should be done.

The timing of the meeting was a concern for the two Republicans on the committee, who noted that the hearing occurred only after a complaint was recently filed against Sen. Nicole Mitchell, DFL-Woodbury, over her alleged attempted first-degree burglary of the Detroit Lakes home of her father's widow.

"The perception is the only reason we have this complaint in front of us now is because the other complaint was filed," Sen. Jeremy Miller, R-Winona, said. Sen. Andrew Mathews, R-Princeton, expressed similar concerns.

For more than two hours, the committee heard from and questioned Maye Quade and Gruenhagen before agreeing on a motion by Sen. Mary Kunesh, DFL-New Brighton, to think about it overnight.

Mathews initially moved for a finding of no probable cause for wrongdoing. But the motion failed on a tie with the two Republicans voting for it and Kunesh and Chair Bobby Joe Champion, DFL-Minneapolis, against it.

Maye Quade argued that by sending a link of gender-affirming surgery to all senators last year, Gruenhagen violated the Senate norms and should be sent to sensitivity training on LGBTQIA+ matters. She said Gruenhagen labeled the contents "extremely graphic and disturbing" and "sent it anyway."

She said the email was gratuitous and not related to pending legislation. "We can and should express our opinions and educate each other about topics," she said, but added that Gruenhagen's email "demonstrated a deep lack of understanding about LGBTQIA+ people."

Sen. Glenn Gruenhagen, R-Glencoe, right, listens as Sen. Erin Maye Quade, DFL-Apple Valley, left, speaks about her ethics complaint against Gruenhagen on Tuesday.

Gruenhagen countered that he was providing information about a bill passed late last April. "We have an obligation and a responsibility to do the research," Gruenhagen said. He said the email linked to an academic, medical video created to train physicians on male to female gender reassignment surgery.

"You had to click twice to get to the videos. You could have hit erase," he said. "What's at stake is whether a member can share information, even if it's explicit, on a bill that's coming before the Senate to vote on."

The bill, which is now law , provided protections from legal repercussions and extradition orders for transgender people and their families traveling to Minnesota for treatment.

Rochelle Olson is a reporter on the politics and government team.

  • Widower sues Ulta, claiming salon denied late wife use of her service dog
  • Myon Burrell arrested on probable cause of narcotics violation
  • What Trump promised oil CEOs as he asked them to steer $1 billion to his campaign

California's budget deficit has likely grown. Gov. Gavin Newsom will reveal his plan to address it

One man was a capitol police officer. the other rioted on jan. 6. they're both running for congress, third week of testimony in trump's hush money trial draws to a close, with michael cohen yet to come.

Trump attorney and Stormy Daniels trade barbs during questions about alleged 2006 sexual encounter

Trump attorney and Stormy Daniels trade barbs during questions about alleged 2006 sexual encounter

Supporters of President Donald Trump fight with police outside the Capitol in Washington, Jan. 6, 2021.

'You're a go': How miscues and confusion delayed the National Guard on Jan. 6

Democratic Sen. Nicole Mitchell, left, was seated next to her attorney Bruce Ringstrom Jr. during the Minnesota Senate ethics hearing Tuesday in St. P

  • What Trump promised oil CEOs as he asked them to steer $1 billion to his campaign • Politics
  • Minnesota Senate passes new penalties for gun straw buyers, bans binary triggers • Politics
  • 'You're a go': How miscues and confusion delayed the National Guard on Jan. 6 • Politics
  • Minnesota agencies too lax on grant safeguards, legislative auditor finds • Politics
  • Ethics panel: Senator who sent graphic video link needs instruction on appropriate emails • Politics

how do they do gender reassignment surgery male to female

© 2024 StarTribune. All rights reserved.

Commentary | Armstrong Williams: The rise of transgenderism…

Share this:.

  • Click to share on Facebook (Opens in new window)
  • Click to share on Twitter (Opens in new window)

Baltimore Sun eNewspaper

  • Readers Respond

Commentary | Armstrong Williams: The rise of transgenderism | STAFF COMMENTARY

Students from Monarch High School in Coconut Creek, Florida, walk out of the school building Nov. 28, 2023, in support of a transgender student who plays on the girls volleyball team. (Joe Cavaretta/South Florida Sun-Sentinel via AP, File)

The roots of the modern transgender movement in America can be traced back to 1952, when Christine Jorgensen publicly announced that she had physically transitioned from male to female through gender reassignment surgery, turning her into an overnight celebrity.  The next year, the film “ Glen or Glenda ” debuted, with a promotional poster proclaiming: “I changed my sex!” In 1960, California chemist Virginia Prince launched a bi-monthly magazine titled Transvestia: The Journal of the American Society for Equality in Dress ; it published for the next 25 years.

Following the launch of Transvestia, the transgender movement experienced rapid expansion, as did awareness of it. In 1966, a group of trans women confronted police in a San Francisco cafe in response to perceived harassment, leading to a riot that spilled into the streets. Three years later, more riots erupted, this time in New York’s Stonewall Inn, with trans activist Marsha Johnson playing a pivotal role in the resistance.

In the 1970s, Minneapolis outlawed discrimination against transgender people, and the U.S. Supreme Court ruled that a transgender woman was eligible to play as female in the U.S. Open. In the 1980s, “gender identity disorder” was added to the Diagnostic and Statistical Manual of Mental Disorders (DSM), though the term was changed to “gender dysphoria” in the 2010s.

Today, the term transgender is widely known, and the left has adopted it as a social cause, even though only 1.6% of adults in America assert that they are transgender or nonbinary, according to a 2022 Pew Research Center survey . Younger adults within that group are most likely to identify as something other than their sex assigned at birth, with 5.1% of those between the ages of 18 and 29 saying they are trans or nonbinary.

Despite the small number of transgender persons in the United States, the movement has permeated many facets of life. This can be attributed to changing education environments in classrooms and social media, among other factors.

The “marked incongruence between their experienced or expressed gender and the one they were assigned at birth” is how the DSM defines gender dysphoria. Its cause remains unknown, and it does not have an agreed-upon course of treatment. The term “gender dysphoria,” has itself become a subject of political controversy.

In some classrooms across the country, educators are raising LGBTQ flags and teaching students in the elementary age range that one’s designated gender at birth may not always reflect their true identity. Such a serious injustice necessitates immediate rectification and reform. Students in elementary school have limited knowledge regarding sexuality. Being informed that they could be a different gender is confusing to them, and, worse, it could influence them.

It is worth noting that research, albeit controversial, has shown that as many as 94% of children who experience gender dysphoria eventually grow out of it and opt not to identify as transgender in their adult lives. However, according to the Trevor Project , a national organization dedicated to preventing suicide among LGBTQ youth, around 60% of transgender youth experience symptoms of depression and 70% experience anxiety.

Depression affects the general population at a much lower rate of approximately 5-6%, according to the World Health Organization. In addition, around 0.5% of the general population in the U.S. has attempted suicide, according to the National Survey of Drug Use and Mental Health. Meanwhile, nearly half of transgender youth have considered suicide and nearly 20% have attempted it.

The first question we must ask is: What is this depression caused by? Could it be, like the media would have you believe, that transgender rights are persistently violated? Of course not. On the contrary, transgender people are thriving. They are protected by numerous state laws, and they are often given more protections by schools than many other classes of students.

Of course, we can’t forget drag story time, where libraries throughout the country invite males dressed in women’s attire to read books to children. It is absolutely unnecessary to expose children to males flamboyantly dressed in women’s clothing in order for them to hear stories. The mind of a child is sacred and must not be exposed to these sorts of things. It can corrupt the mind and may lead innocent children down the road of gender dysphoria and ultimately depression.

Tragically, transgenderism has compromised the rights of biological women. Undoubtedly, women continue to advocate for equality in the United States as they face significant disparities in the workforce and in public life. However, prior to the complete realization of gender equality for women, transgenderism emerged and complicated the situation. As a result, males are now beating women in all aspects of life. Do you recall in 2015, when Caitlyn Jenner was named one of Glamour Magazine’s “Women of the Year”? The recipient of that award was not a woman who had struggled her entire life to be a woman in a world dominated by men. The recipient was a biological male formerly known as Bruce.

Likewise, transgenderism has entered the realm of athletics. Unsurprisingly, biological males identifying as transgender have emerged victorious in athletic competitions against biological women on a multitude of occasions. Biological men have won significant accolades against biological women in swimming , golf  and even weightlifting , the sport that exemplifies strength disparities. Men who have undergone the “transition” from male to female are often found to have been mediocre, at best, among their male counterparts, but they prove superior when they begin competing against women.

How about sex changes for minors? It should be obvious that the notion that a confused child should undertake surgical gender transition from their biological sex to an alternative gender is utterly absurd and repugnant to the average person. However, 54% of Americans oppose legislation that criminalizes providing medical care for gender transition to minors. Both science and common sense support the notion that it is not until the mid-to-late 20s, that the brain reaches complete maturity and development. This is the reason why children often engage in foolish behavior without contemplating the repercussions and why a contract formed by a child is deemed void in legal terms. Yet, when it comes to transgenderism, all of that goes out the window and delusion seems to take over.

The facts are quite simple: Men are not women, and women are not men. This is the reality that everyone on Earth must face. Those who experience gender dysphoria need treatment, not encouragement in their confusion. For too long, America has allowed itself to be divided and degraded along lines of common sense by the transgender movement. Unless those with rational minds lose their reluctance to opine on the matter, the utter insanity of the the transgender movement will, like a cancer, continue to persist.

Armstrong Williams ([email protected]; @arightside) is a political analyst, syndicated columnist and owner of the broadcasting company, Howard Stirk Holdings. He is also part owner of The Baltimore Sun.

More in Commentary

Effecting lasting and real change to a culture of gun violence takes dedication, patience, resources and cooperation among many parties.

Commentary | Mayor Brandon Scott’s seeds are bearing fruit; he deserves credit for violence reduction | GUEST COMMENTARY

Baltimore’s one-year drop in gun violence is a success, and success, as they say, has many fathers.

Commentary | Gun violence down in Baltimore, but Mayor Scott can’t credibly take credit | GUEST COMMENTARY

We need to move quickly to move kids away from social media or the next generation will be unprepared for the challenges of adulthood.

Commentary | Abandoning children to the internet has dire consequences, just ask Gen Z | GUEST COMMENTARY

Ranked-choice voting allows voters to rank candidates in order of preference. With some simple changes to the ballot, Maryland voters could have this option.

Commentary | Marylanders deserve ranked-choice voting | GUEST COMMENTARY

how do they do gender reassignment surgery male to female

Court rules against mandating transgender surgery to change legal sex status

transgender surgery-sex status

YEONGDONG, South Korea, May 8 (Yonhap) -- A regional court on Wednesday approved the change of gender from male to female for five transgender people without sex reassignment surgery, saying it is against the law to determine whether to allow gender change based on surgery.

The court in the central county of Yeongdong handed down the ruling, saying all human beings have the right to live according to their own gender identity and demanding surgical operations for transgender people amounts to demanding them to violate their own physical integrity.

The five people were assigned male at birth but have strongly identified as women since they were young and have been receiving transgender hormone therapy for years.

The current court guidelines stipulate that an applicant must undergo sex reassignment surgery and be recognized for the change in their physical qualities, including their external genital organs, and verify they lost fertility as a result of the operation, with a slim probability of it being reversed.

The guidelines have been downgraded to be used as reference, and not criteria, but some courts have still grounded their rulings on it to dismiss the requests of those who did not go through gender-affirming surgery, the court noted.

"Every human being has the right to form their character and live a life according to one's gender identity, and so do transgender people, who should be able to pursue happiness as an equal member of society," the court said.

Song Ji-eun, the legal representative in the case, said the ruling is significant in that it called into question the past court rulings made solely through court guidelines.

[email protected]

A civic group holds a press briefing to file a complaint with the human rights watchdog to abolish the criteria that mandates sex reassignment surgery in order to change legal sex status, in this file photo taken Nov. 16, 2021. (Yonhap)

Court says state health-care plans can’t exclude gender-affirming surgery

how do they do gender reassignment surgery male to female

A federal appellate court in Richmond became the first in the country to rule that state health-care plans must pay for gender-affirming surgeries, a major win for transgender rights amid a nationwide wave of anti-trans activism and legislation.

The decision came from a set of cases out of North Carolina and West Virginia, where state officials argued that their policies were based on cost concerns rather than bias. The U.S. Court of Appeals for the 4th Circuit rejected that argument, saying the plans were discriminating against trans people in need of treatment.

Judge Roger L. Gregory, an appointee of President Bill Clinton, wrote for the majority that the restrictions were “obviously discriminatory” based on both sex and gender.

“In this case, discriminating on the basis of diagnosis is discriminating on the basis of gender identity and sex,” Gregory wrote, because “gender dysphoria is so intimately related to transgender status as to be virtually indistinguishable from it.”

The majority ruled that West Virginia’s policy also violated the Affordable Care Act’s anti-discrimination provision, a finding that has broad implications for other states’ Medicaid programs.

It’s the second ruling in favor of trans rights this month from the 4th Circuit, a once-conservative court that has become a trailblazer in the realm of transgender rights. The court was the first to say trans students had a right to use the bathrooms that align with their gender identity and the first to recognize gender dysphoria as a protected disability. Earlier this month, the court said a federally funded middle school could not ban a trans 13-year-old from playing on the girls’ track and field team.

The decision will be appealed to the Supreme Court, which recently allowed Idaho to enforce a ban on gender-affirming care for minors. West Virginia Attorney General Patrick Morrisey, who is running for governor, said in a statement Monday that he would “take this up to the Supreme Court and win.”

But the conservative-led Supreme Court has been reluctant to engage on these issues, letting multiple 4th Circuit rulings in favor of transgender rights stand. The court also generally waits until there is disagreement between circuit courts before getting involved.

All of these rulings split the 4th Circuit court down ideological lines, with judges appointed by Democrats joining the majority opinion and those appointed by Republicans dissenting. In the lead dissent from the ruling Monday, Judge Jay Richardson, a Trump appointee, wrote that there was no role for the federal court in policing what treatments health-care plans decide to cover.

The majority opinion, Richardson wrote, “treats these cases as new fronts upon which this conflict must be waged. But not every battle is part of a larger war. In the majority’s haste to champion plaintiffs’ cause, today’s result oversteps the bounds of the law.”

Richardson said what mattered is that trans patients have the same coverage of the same conditions as others. For example, he said, a trans patient with uterine cancer could get a hysterectomy under these plans.

“The different coverage accorded to treatments for different diagnoses is … based on medical judgment of biological reality,” he wrote. “States can reasonably decide that certain gender-dysphoria services are not cost-justified, in part because they question the services’ medical efficacy and necessity.”

Other states have banned hormonal treatment and surgery for trans minors; some have restricted care for transgender adults as well. Multiple other states have similar laws against insurance coverage for transition-related treatment. The Biden administration has moved to protect trans Americans through federal regulations, including guidelines released Monday that treat misuse of pronouns or refusal to let transgender employees use their preferred bathroom as workplace harassment.

In West Virginia, transgender Medicaid users challenged the state’s program, which since 2004 has by law banned “transsexual surgeries.” In North Carolina, state employees challenged their coverage, which in 2018 excluded surgical treatment of gender dysphoria — the clinical diagnosis of a disconnect between a person’s gender and birth sex.

Both states insisted that there was no bias in their coverage limitations, only cost concerns. Trans patients, they argued, were entitled to the same health treatments as everyone else but not specialized care.

“There is no service that is covered for a cisgendered person that is not covered for a transgender person meeting the same criteria,” Caleb David, an attorney for West Virginia, told judges on the appellate court during the oral argument. David added that the state had decided to provide psychiatric and hormonal treatment for gender dysphoria — just not surgery.

Advocates for trans patients said there was no medical justification for drawing the line there, when the state would cover such procedures for other conditions. They also said the financial explanation was suspect because so few people get gender-affirming surgery. It’s “a drop in the bucket,” Lambda Legal attorney Tara Borelli said during oral arguments. But even if the cost was significant, she argued, the cost of public health insurance “has to be a shared burden. It can’t be shunted onto the backs of a vulnerable minority group.”

The court agreed, saying cost-cutting could not justify covering the same treatments for health concerns other than gender dysphoria. For example, Gregory noted that under these plans, “cisgender people do receive coverage for certain gender-affirming surgeries,” including breast reconstruction for cancer patients after a mastectomy.

North Carolina began covering gender-affirming care in 2017 and stopped the following year, when Republican Dale Folwell became state treasurer. Julia McKeown, a professor at North Carolina State University, accepted her job in 2016, a few years into fully transitioning after a lifetime of “being adamant about what my gender was” but being limited in expressing it. She spent months preparing for surgery, only to be forced to cover the full cost along with all other treatment.

“It’s like having the rug pulled out from under you,” she said. “In some ways it’s worse than going in and knowing it was going to be denied.” She cut into her retirement savings rather than delay the surgery, calling herself “fortunate” to be able to do so.

McKeown grew up in a rural town in Florida and spent years pretending to be a man for fear of social and professional exclusion. Joining the lawsuit meant exposing herself to hate mail from strangers.

“In an ideal world, I would have loved to just move on with my life” after the surgery, she said. “At the same time, I feel a moral obligation to help those who can’t speak up for themselves, and for those who risk being fired or who have dependents on the state health-care plan who need access to treatment.”

Twenty-one Republican-led states asked the court to rule against the plaintiffs, focusing on disagreement over what physical interventions should be available to trans youth. But most major medical plans and the federal government cover gender transition treatment, which has been endorsed by mainstream medical associations. Studies indicate very few people who transition regret doing so or seek to reverse the changes, including those who start treatment in their teens.

Seventeen Democratic-led states and the District of Columbia urged the court to rule for the coverage, saying their “experience demonstrates that protecting access to gender-affirming care improves health outcomes for our transgender residents at little cost.”

An earlier version of this story reported that the contested insurance plans covered mastectomies for cancer patients but not for trans women. The plans covered mastectomies for all cancer patients, but did not cover the procedure for trans men who wanted their breasts removed to treat gender dysphoria.

how do they do gender reassignment surgery male to female

IMAGES

  1. How Gender Reassignment Surgery Works (Infographic)

    how do they do gender reassignment surgery male to female

  2. What it’s Really Like to Have Female to Male Gender Reassignment

    how do they do gender reassignment surgery male to female

  3. Surgical Reconstruction for Male-to-Female Sex Reassignment

    how do they do gender reassignment surgery male to female

  4. What it’s Really Like to Have Female to Male Gender Reassignment

    how do they do gender reassignment surgery male to female

  5. Stunning Before And After Photos Depict The Journey Of Gender

    how do they do gender reassignment surgery male to female

  6. The Role of Nasal Feminization Rhinoplasty in Male-to-Female Gender

    how do they do gender reassignment surgery male to female

VIDEO

  1. Gender Reassignment Surgery (POWER OUTAGE + DETAILS)

  2. Gender reassignment surgery male to female surgery slowed version part 4

  3. Things I didn't expect after gender reassignment surgery |Transgender MTF

  4. Gender reassignment surgery😄😅 "Do i contradict myself? Whatever, i contain multitudes" W. Whitman😄

  5. The BEST Doctor For Sexual Reassignment Surgery.. (SRS)

  6. Gender Reassignment Surgery at Hera Hebe: Empowering Authentic Self-Expression

COMMENTS

  1. How Gender Reassignment Surgery Works (Infographic)

    The cost for female-to-male reassignment can be more than $50,000. The cost for male-to-female reassignment can be $7,000 to $24,000. Between 100 to 500 gender-reassignment procedures are ...

  2. Vaginoplasty for Gender Affirmation

    Gender affirming surgery can be used to create a vulva and vagina. It involves removing the penis, testicles and scrotum. During a vaginoplasty procedure, tissue in the genital area is rearranged to create a vaginal canal (or opening) and vulva (external genitalia), including the labia. A version of vaginoplasty called vulvoplasty can create a ...

  3. Gender Affirming Surgery: Before and After Photos

    Breast augmentation is often performed as an outpatient procedure but some patients may require one night stay in the hospital. See before and after photos of patients who have undergone gender-affirming surgeries at Cleveland Clinic, including breast augmentations, facial feminizations, mastectomies and vaginoplasty.

  4. Gender-affirming surgery (male-to-female)

    Gender-affirming surgery for male-to-female transgender women or transfeminine non-binary people describes a variety of surgical procedures that alter the body to provide physical traits more comfortable and affirming to an individual's gender identity and overall functioning.. Often used to refer to vaginoplasty, sex reassignment surgery can also more broadly refer to other gender-affirming ...

  5. Gender Affirmation Surgery: What Happens, Benefits & Recovery

    Research consistently shows that people who choose gender affirmation surgery experience reduced gender incongruence and improved quality of life. Depending on the procedure, 94% to 100% of people report satisfaction with their surgery results. Gender-affirming surgery provides long-term mental health benefits, too.

  6. Gender Confirmation Surgery

    The cost of transitioning can often exceed $100,000 in the United States, depending upon the procedures needed. A typical genitoplasty alone averages about $18,000. Rhinoplasty, or a nose job, averaged $5,409 in 2019. Insurance Coverage for Sex Reassignment Surgery.

  7. Vaginoplasty: Male to Female (MTF) Genital Reconstructive Surgery

    Your surgeon will give you general guidelines for this as well. Approximately 1 out of 10 people who have a vaginoplasty end up requiring a second, minor surgery to correct some of the scarring from the first surgery and improve the function and cosmetic appearance. Most genital gender affirmation surgeries are covered by insurance.

  8. Feminizing surgery

    Overview. Feminizing surgery, also called gender-affirming surgery or gender-confirmation surgery, involves procedures that help better align the body with a person's gender identity. Feminizing surgery includes several options, such as top surgery to increase the size of the breasts. That procedure also is called breast augmentation.

  9. Frontiers

    Purpose: Gender dysphoria (GD) is an incompatibility between biological sex and personal gender identity; individuals harbor an unalterable conviction that they were born in the wrong body, which causes personal suffering. In this context, surgery is imperative to achieve a successful gender transition and plays a key role in alleviating the associated psychological discomfort. In the current ...

  10. Gender Affirmation Surgery: A Guide

    A gender affirmation surgery allows individuals, such as those who identify as transgender or nonbinary, to change one or more of their sex characteristics. This type of procedure offers a person ...

  11. Phalloplasty for Gender Affirmation

    Featured Expert: Fan Liang, M.D. Phalloplasty is surgery for masculinizing gender affirmation. Phalloplasty is a multistaged process that may include a variety of procedures, including: Creating the penis. Lengthening the urethra so you are able to stand to urinate. Creating the tip (glans) of the penis. Creating the scrotum.

  12. Gender Affirmation Surgeries: Common Questions and Answers

    Overview. Gender affirmation surgery, also known as gender confirmation surgery, is performed to align or transition individuals with gender dysphoria to their true gender. A transgender woman, man, or non-binary person may choose to undergo gender affirmation surgery. The term "transexual" was previously used by the medical community to ...

  13. A Pioneering Approach to Gender Affirming Surgery From a World Leader

    Miroslav Djordjevic, MD, PhD, an internationally renowned surgeon and a leading authority on surgery for transgender individuals, is developing a procedure to match two patients undergoing transgender surgery—one male-to-female, the other female-to-male—and transfer the genitalia between these live donors in a one-stage procedure instead of discarding them as is done now.

  14. Gender-affirming surgery: Male to female

    Medical treatment often includes hormones to expose sex steroid-responsive target tissues to more estrogen and block androgen action. Commonly performed surgeries include facial feminization (craniomaxillofacial procedures), chest ("top") surgery (eg, breast augmentation), and genital ("bottom") surgery (eg, orchiectomy and vaginoplasty).

  15. Here's how sex reassignment surgery works

    In female to male surgery, the breasts, uterus and ovaries are removed (in two separate procedures). ... institutions to perform sex reassignment surgery, halted the practice when officials ...

  16. What transgender women can expect after gender-affirming surgery

    Sex and sexual health tips for transgender women after gender-affirming surgery. Sex after surgery. Achieving orgasm. Libido. Vaginal depth and lubrication. Aftercare. Contraceptions and STIs ...

  17. Gender-affirming surgery (female-to-male)

    Gender-affirming surgery for female-to-male transgender people includes a variety of surgical procedures that alter anatomical traits to provide physical traits more comfortable to the trans man's male identity and functioning. Often used to refer to phalloplasty, metoidoplasty, or vaginectomy, sex reassignment surgery can also more broadly ...

  18. How does female-to-male surgery work?

    This procedure involves changing the clitoris into a penis. A person will receive hormone therapy before the surgery to enlarge the clitoris for this purpose. During the procedure, the surgeon ...

  19. Gender-affirming surgery for trans men: What to expect from sex

    Summary. Transgender men may choose to have gender-affirming surgery, such as metoidioplasty or phalloplasty. These may provide sensations and functions including erections and urinating standing ...

  20. Male-to-Female Gender-Affirming Surgery: 20-Year Review of Technique

    Purpose: Gender dysphoria (GD) is an incompatibility between biological sex and personal gender identity; individuals harbor an unalterable conviction that they were born in the wrong body, which causes personal suffering. In this context, surgery is imperative to achieve a successful gender transition and plays a key role in alleviating the associated psychological discomfort.

  21. An overview of female-to-male gender-confirming surgery

    Gender transition can substantially improve quality-of-life in individuals with gender dysphoria, and various surgical options are available for female-to-male (FtM) transition, including facial ...

  22. Sex Reassignment Surgery in the Female-to-Male Transsexual

    The two major sex reassignment surgery (SRS) interventions in the female-to-male transsexual patients that will be addressed here are (1) the subcutaneous mastectomy (SCM), often combined with a hysterectomy/ ovariectomy; and (2) the actual genital transformation consisting of vaginectomy, reconstruction of the fixed part of the urethra (if ...

  23. Gender-Reassignment Surgery: Everything You Need to Know

    Gender surgery, such as gender-affirming surgeries, is typically considered permanent as it involves irreversible alterations to one's anatomy to align with their gender identity. Published on May ...

  24. Gender-Reassignment Surgery: Everything You Need to Know

    Female-to-Male Genital Sex Reassignment (Phalloplasty): Phalloplasty is a surgical procedure to construct a phallus for FtM individuals seeking male genitalia. The radial forearm flap method is ...

  25. Ethics panel takes up complaint against Republican senator who sent

    He said the email linked to an academic, medical video created to train physicians on male to female gender reassignment surgery. "You had to click twice to get to the videos. You could have hit ...

  26. Armstrong Williams: The rise of transgenderism

    Younger adults within that group are most likely to identify as something other than their sex assigned at birth, with 5.1% of those between the ages of 18 and 29 saying they are trans or nonbinary.

  27. Court rules against mandating transgender surgery to change legal sex

    transgender surgery-sex status. YEONGDONG, South Korea, May 8 (Yonhap) -- A regional court on Wednesday approved the change of gender from male to female for five transgender people without sex ...

  28. Court says state health-care plans can't exclude gender-affirming surgery

    A federal appellate court in Richmond became the first in the country to rule that state health-care plans must pay for gender-affirming surgeries, a major win for transgender rights amid a ...

  29. Enforcement Guidance on Harassment in the Workplace

    More than once, Josh exposed himself to Eric. Based on these facts, Josh targeted Eric based on his perception that Eric did not conform to traditional male stereotypes and subjected Eric to harassment based on sex. 104. Example 31: Causation Established Based on Sex Stereotyping. Maria, a receptionist, has recently experienced domestic violence.