what is a synthesis of the literature

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  • 6. Synthesize
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Synthesis matrix example.

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  • Synthesis Worksheet

About Synthesis

What is synthesis? What synthesis is NOT:

Approaches to Synthesis

You can sort the literature in various ways, for example:

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How to Begin?

Read your sources carefully and find the main idea(s) of each source

Look for similarities in your sources – which sources are talking about the same main ideas? (for example, sources that discuss the historical background on your topic)

Use the worksheet (above) or synthesis matrix (below) to get organized

This work can be messy. Don't worry if you have to go through a few iterations of the worksheet or matrix as you work on your lit review!

Four Examples of Student Writing

In the four examples below, only ONE shows a good example of synthesis: the fourth column, or  Student D . For a web accessible version, click the link below the image.

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what is a synthesis of the literature

Literature Syntheis 101

How To Synthesise The Existing Research (With Examples)

By: Derek Jansen (MBA) | Expert Reviewer: Eunice Rautenbach (DTech) | August 2023

One of the most common mistakes that students make when writing a literature review is that they err on the side of describing the existing literature rather than providing a critical synthesis of it. In this post, we’ll unpack what exactly synthesis means and show you how to craft a strong literature synthesis using practical examples.

This post is based on our popular online course, Literature Review Bootcamp . In the course, we walk you through the full process of developing a literature review, step by step. If it’s your first time writing a literature review, you definitely want to use this link to get 50% off the course (limited-time offer).

Overview: Literature Synthesis

  • What exactly does “synthesis” mean?
  • Aspect 1: Agreement
  • Aspect 2: Disagreement
  • Aspect 3: Key theories
  • Aspect 4: Contexts
  • Aspect 5: Methodologies
  • Bringing it all together

What does “synthesis” actually mean?

As a starting point, let’s quickly define what exactly we mean when we use the term “synthesis” within the context of a literature review.

Simply put, literature synthesis means going beyond just describing what everyone has said and found. Instead, synthesis is about bringing together all the information from various sources to present a cohesive assessment of the current state of knowledge in relation to your study’s research aims and questions .

Put another way, a good synthesis tells the reader exactly where the current research is “at” in terms of the topic you’re interested in – specifically, what’s known , what’s not , and where there’s a need for more research .

So, how do you go about doing this?

Well, there’s no “one right way” when it comes to literature synthesis, but we’ve found that it’s particularly useful to ask yourself five key questions when you’re working on your literature review. Having done so,  you can then address them more articulately within your actual write up. So, let’s take a look at each of these questions.

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1. Points Of Agreement

The first question that you need to ask yourself is: “Overall, what things seem to be agreed upon by the vast majority of the literature?”

For example, if your research aim is to identify which factors contribute toward job satisfaction, you’ll need to identify which factors are broadly agreed upon and “settled” within the literature. Naturally, there may at times be some lone contrarian that has a radical viewpoint , but, provided that the vast majority of researchers are in agreement, you can put these random outliers to the side. That is, of course, unless your research aims to explore a contrarian viewpoint and there’s a clear justification for doing so. 

Identifying what’s broadly agreed upon is an essential starting point for synthesising the literature, because you generally don’t want (or need) to reinvent the wheel or run down a road investigating something that is already well established . So, addressing this question first lays a foundation of “settled” knowledge.

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what is a synthesis of the literature

2. Points Of Disagreement

Related to the previous point, but on the other end of the spectrum, is the equally important question: “Where do the disagreements lie?” .

In other words, which things are not well agreed upon by current researchers? It’s important to clarify here that by disagreement, we don’t mean that researchers are (necessarily) fighting over it – just that there are relatively mixed findings within the empirical research , with no firm consensus amongst researchers.

This is a really important question to address as these “disagreements” will often set the stage for the research gap(s). In other words, they provide clues regarding potential opportunities for further research, which your study can then (hopefully) contribute toward filling. If you’re not familiar with the concept of a research gap, be sure to check out our explainer video covering exactly that .

what is a synthesis of the literature

3. Key Theories

The next question you need to ask yourself is: “Which key theories seem to be coming up repeatedly?” .

Within most research spaces, you’ll find that you keep running into a handful of key theories that are referred to over and over again. Apart from identifying these theories, you’ll also need to think about how they’re connected to each other. Specifically, you need to ask yourself:

  • Are they all covering the same ground or do they have different focal points  or underlying assumptions ?
  • Do some of them feed into each other and if so, is there an opportunity to integrate them into a more cohesive theory?
  • Do some of them pull in different directions ? If so, why might this be?
  • Do all of the theories define the key concepts and variables in the same way, or is there some disconnect? If so, what’s the impact of this ?

Simply put, you’ll need to pay careful attention to the key theories in your research area, as they will need to feature within your theoretical framework , which will form a critical component within your final literature review. This will set the foundation for your entire study, so it’s essential that you be critical in this area of your literature synthesis.

If this sounds a bit fluffy, don’t worry. We deep dive into the theoretical framework (as well as the conceptual framework) and look at practical examples in Literature Review Bootcamp . If you’d like to learn more, take advantage of our limited-time offer to get 60% off the standard price.

what is a synthesis of the literature

4. Contexts

The next question that you need to address in your literature synthesis is an important one, and that is: “Which contexts have (and have not) been covered by the existing research?” .

For example, sticking with our earlier hypothetical topic (factors that impact job satisfaction), you may find that most of the research has focused on white-collar , management-level staff within a primarily Western context, but little has been done on blue-collar workers in an Eastern context. Given the significant socio-cultural differences between these two groups, this is an important observation, as it could present a contextual research gap .

In practical terms, this means that you’ll need to carefully assess the context of each piece of literature that you’re engaging with, especially the empirical research (i.e., studies that have collected and analysed real-world data). Ideally, you should keep notes regarding the context of each study in some sort of catalogue or sheet, so that you can easily make sense of this before you start the writing phase. If you’d like, our free literature catalogue worksheet is a great tool for this task.

5. Methodological Approaches

Last but certainly not least, you need to ask yourself the question: “What types of research methodologies have (and haven’t) been used?”

For example, you might find that most studies have approached the topic using qualitative methods such as interviews and thematic analysis. Alternatively, you might find that most studies have used quantitative methods such as online surveys and statistical analysis.

But why does this matter?

Well, it can run in one of two potential directions . If you find that the vast majority of studies use a specific methodological approach, this could provide you with a firm foundation on which to base your own study’s methodology . In other words, you can use the methodologies of similar studies to inform (and justify) your own study’s research design .

On the other hand, you might argue that the lack of diverse methodological approaches presents a research gap , and therefore your study could contribute toward filling that gap by taking a different approach. For example, taking a qualitative approach to a research area that is typically approached quantitatively. Of course, if you’re going to go against the methodological grain, you’ll need to provide a strong justification for why your proposed approach makes sense. Nevertheless, it is something worth at least considering.

Regardless of which route you opt for, you need to pay careful attention to the methodologies used in the relevant studies and provide at least some discussion about this in your write-up. Again, it’s useful to keep track of this on some sort of spreadsheet or catalogue as you digest each article, so consider grabbing a copy of our free literature catalogue if you don’t have anything in place.

Looking at the methodologies of existing, similar studies will help you develop a strong research methodology for your own study.

Bringing It All Together

Alright, so we’ve looked at five important questions that you need to ask (and answer) to help you develop a strong synthesis within your literature review.  To recap, these are:

  • Which things are broadly agreed upon within the current research?
  • Which things are the subject of disagreement (or at least, present mixed findings)?
  • Which theories seem to be central to your research topic and how do they relate or compare to each other?
  • Which contexts have (and haven’t) been covered?
  • Which methodological approaches are most common?

Importantly, you’re not just asking yourself these questions for the sake of asking them – they’re not just a reflection exercise. You need to weave your answers to them into your actual literature review when you write it up. How exactly you do this will vary from project to project depending on the structure you opt for, but you’ll still need to address them within your literature review, whichever route you go.

The best approach is to spend some time actually writing out your answers to these questions, as opposed to just thinking about them in your head. Putting your thoughts onto paper really helps you flesh out your thinking . As you do this, don’t just write down the answers – instead, think about what they mean in terms of the research gap you’ll present , as well as the methodological approach you’ll take . Your literature synthesis needs to lay the groundwork for these two things, so it’s essential that you link all of it together in your mind, and of course, on paper.

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How to Synthesize Written Information from Multiple Sources

Shona McCombes

Content Manager

B.A., English Literature, University of Glasgow

Shona McCombes is the content manager at Scribbr, Netherlands.

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Saul McLeod, PhD

Editor-in-Chief for Simply Psychology

BSc (Hons) Psychology, MRes, PhD, University of Manchester

Saul McLeod, PhD., is a qualified psychology teacher with over 18 years of experience in further and higher education. He has been published in peer-reviewed journals, including the Journal of Clinical Psychology.

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When you write a literature review or essay, you have to go beyond just summarizing the articles you’ve read – you need to synthesize the literature to show how it all fits together (and how your own research fits in).

Synthesizing simply means combining. Instead of summarizing the main points of each source in turn, you put together the ideas and findings of multiple sources in order to make an overall point.

At the most basic level, this involves looking for similarities and differences between your sources. Your synthesis should show the reader where the sources overlap and where they diverge.

Unsynthesized Example

Franz (2008) studied undergraduate online students. He looked at 17 females and 18 males and found that none of them liked APA. According to Franz, the evidence suggested that all students are reluctant to learn citations style. Perez (2010) also studies undergraduate students. She looked at 42 females and 50 males and found that males were significantly more inclined to use citation software ( p < .05). Findings suggest that females might graduate sooner. Goldstein (2012) looked at British undergraduates. Among a sample of 50, all females, all confident in their abilities to cite and were eager to write their dissertations.

Synthesized Example

Studies of undergraduate students reveal conflicting conclusions regarding relationships between advanced scholarly study and citation efficacy. Although Franz (2008) found that no participants enjoyed learning citation style, Goldstein (2012) determined in a larger study that all participants watched felt comfortable citing sources, suggesting that variables among participant and control group populations must be examined more closely. Although Perez (2010) expanded on Franz’s original study with a larger, more diverse sample…

Step 1: Organize your sources

After collecting the relevant literature, you’ve got a lot of information to work through, and no clear idea of how it all fits together.

Before you can start writing, you need to organize your notes in a way that allows you to see the relationships between sources.

One way to begin synthesizing the literature is to put your notes into a table. Depending on your topic and the type of literature you’re dealing with, there are a couple of different ways you can organize this.

Summary table

A summary table collates the key points of each source under consistent headings. This is a good approach if your sources tend to have a similar structure – for instance, if they’re all empirical papers.

Each row in the table lists one source, and each column identifies a specific part of the source. You can decide which headings to include based on what’s most relevant to the literature you’re dealing with.

For example, you might include columns for things like aims, methods, variables, population, sample size, and conclusion.

For each study, you briefly summarize each of these aspects. You can also include columns for your own evaluation and analysis.

summary table for synthesizing the literature

The summary table gives you a quick overview of the key points of each source. This allows you to group sources by relevant similarities, as well as noticing important differences or contradictions in their findings.

Synthesis matrix

A synthesis matrix is useful when your sources are more varied in their purpose and structure – for example, when you’re dealing with books and essays making various different arguments about a topic.

Each column in the table lists one source. Each row is labeled with a specific concept, topic or theme that recurs across all or most of the sources.

Then, for each source, you summarize the main points or arguments related to the theme.

synthesis matrix

The purposes of the table is to identify the common points that connect the sources, as well as identifying points where they diverge or disagree.

Step 2: Outline your structure

Now you should have a clear overview of the main connections and differences between the sources you’ve read. Next, you need to decide how you’ll group them together and the order in which you’ll discuss them.

For shorter papers, your outline can just identify the focus of each paragraph; for longer papers, you might want to divide it into sections with headings.

There are a few different approaches you can take to help you structure your synthesis.

If your sources cover a broad time period, and you found patterns in how researchers approached the topic over time, you can organize your discussion chronologically .

That doesn’t mean you just summarize each paper in chronological order; instead, you should group articles into time periods and identify what they have in common, as well as signalling important turning points or developments in the literature.

If the literature covers various different topics, you can organize it thematically .

That means that each paragraph or section focuses on a specific theme and explains how that theme is approached in the literature.

synthesizing the literature using themes

Source Used with Permission: The Chicago School

If you’re drawing on literature from various different fields or they use a wide variety of research methods, you can organize your sources methodologically .

That means grouping together studies based on the type of research they did and discussing the findings that emerged from each method.

If your topic involves a debate between different schools of thought, you can organize it theoretically .

That means comparing the different theories that have been developed and grouping together papers based on the position or perspective they take on the topic, as well as evaluating which arguments are most convincing.

Step 3: Write paragraphs with topic sentences

What sets a synthesis apart from a summary is that it combines various sources. The easiest way to think about this is that each paragraph should discuss a few different sources, and you should be able to condense the overall point of the paragraph into one sentence.

This is called a topic sentence , and it usually appears at the start of the paragraph. The topic sentence signals what the whole paragraph is about; every sentence in the paragraph should be clearly related to it.

A topic sentence can be a simple summary of the paragraph’s content:

“Early research on [x] focused heavily on [y].”

For an effective synthesis, you can use topic sentences to link back to the previous paragraph, highlighting a point of debate or critique:

“Several scholars have pointed out the flaws in this approach.” “While recent research has attempted to address the problem, many of these studies have methodological flaws that limit their validity.”

By using topic sentences, you can ensure that your paragraphs are coherent and clearly show the connections between the articles you are discussing.

As you write your paragraphs, avoid quoting directly from sources: use your own words to explain the commonalities and differences that you found in the literature.

Don’t try to cover every single point from every single source – the key to synthesizing is to extract the most important and relevant information and combine it to give your reader an overall picture of the state of knowledge on your topic.

Step 4: Revise, edit and proofread

Like any other piece of academic writing, synthesizing literature doesn’t happen all in one go – it involves redrafting, revising, editing and proofreading your work.

Checklist for Synthesis

  •   Do I introduce the paragraph with a clear, focused topic sentence?
  •   Do I discuss more than one source in the paragraph?
  •   Do I mention only the most relevant findings, rather than describing every part of the studies?
  •   Do I discuss the similarities or differences between the sources, rather than summarizing each source in turn?
  •   Do I put the findings or arguments of the sources in my own words?
  •   Is the paragraph organized around a single idea?
  •   Is the paragraph directly relevant to my research question or topic?
  •   Is there a logical transition from this paragraph to the next one?

Further Information

How to Synthesise: a Step-by-Step Approach

Help…I”ve Been Asked to Synthesize!

Learn how to Synthesise (combine information from sources)

How to write a Psychology Essay

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Get Organized

  • Lit Review Prep Use this template to help you evaluate your sources, create article summaries for an annotated bibliography, and a synthesis matrix for your lit review outline.

Synthesize your Information

Synthesize: combine separate elements to form a whole.

Synthesis Matrix

A synthesis matrix helps you record the main points of each source and document how sources relate to each other.

After summarizing and evaluating your sources, arrange them in a matrix or use a citation manager to help you see how they relate to each other and apply to each of your themes or variables.  

By arranging your sources by theme or variable, you can see how your sources relate to each other, and can start thinking about how you weave them together to create a narrative.

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Literature reviews: synthesis.

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Synthesise Information

So, how can you create paragraphs within your literature review that demonstrates your knowledge of the scholarship that has been done in your field of study?  

You will need to present a synthesis of the texts you read.  

Doug Specht, Senior Lecturer at the Westminster School of Media and Communication, explains synthesis for us in the following video:  

Synthesising Texts  

What is synthesis? 

Synthesis is an important element of academic writing, demonstrating comprehension, analysis, evaluation and original creation.  

With synthesis you extract content from different sources to create an original text. While paraphrase and summary maintain the structure of the given source(s), with synthesis you create a new structure.  

The sources will provide different perspectives and evidence on a topic. They will be put together when agreeing, contrasted when disagreeing. The sources must be referenced.  

Perfect your synthesis by showing the flow of your reasoning, expressing critical evaluation of the sources and drawing conclusions.  

When you synthesise think of "using strategic thinking to resolve a problem requiring the integration of diverse pieces of information around a structuring theme" (Mateos and Sole 2009, p448). 

Synthesis is a complex activity, which requires a high degree of comprehension and active engagement with the subject. As you progress in higher education, so increase the expectations on your abilities to synthesise. 

How to synthesise in a literature review: 

Identify themes/issues you'd like to discuss in the literature review. Think of an outline.  

Read the literature and identify these themes/issues.  

Critically analyse the texts asking: how does the text I'm reading relate to the other texts I've read on the same topic? Is it in agreement? Does it differ in its perspective? Is it stronger or weaker? How does it differ (could be scope, methods, year of publication etc.). Draw your conclusions on the state of the literature on the topic.  

Start writing your literature review, structuring it according to the outline you planned.  

Put together sources stating the same point; contrast sources presenting counter-arguments or different points.  

Present your critical analysis.  

Always provide the references. 

The best synthesis requires a "recursive process" whereby you read the source texts, identify relevant parts, take notes, produce drafts, re-read the source texts, revise your text, re-write... (Mateos and Sole, 2009). 

What is good synthesis?  

The quality of your synthesis can be assessed considering the following (Mateos and Sole, 2009, p439):  

Integration and connection of the information from the source texts around a structuring theme. 

Selection of ideas necessary for producing the synthesis. 

Appropriateness of the interpretation.  

Elaboration of the content.  

Example of Synthesis

Original texts (fictitious): 

Animal testing is necessary to save human lives. Incidents have happened where humans have died or have been seriously harmed for using drugs that had not been tested on animals (Smith 2008).   

Animals feel pain in a way that is physiologically and neuroanatomically similar to humans (Chowdhury 2012).   

Animal testing is not always used to assess the toxicology of a drug; sometimes painful experiments are undertaken to improve the effectiveness of cosmetics (Turner 2015) 

Animals in distress can suffer psychologically, showing symptoms of depression and anxiety (Panatta and Hudson 2016). 

  

Synthesis: 

Animal experimentation is a subject of heated debate. Some argue that painful experiments should be banned. Indeed it has been demonstrated that such experiments make animals suffer physically and psychologically (Chowdhury 2012; Panatta and Hudson 2016). On the other hand, it has been argued that animal experimentation can save human lives and reduce harm on humans (Smith 2008). This argument is only valid for toxicological testing, not for tests that, for example, merely improve the efficacy of a cosmetic (Turner 2015). It can be suggested that animal experimentation should be regulated to only allow toxicological risk assessment, and the suffering to the animals should be minimised.   

Bibliography

Mateos, M. and Sole, I. (2009). Synthesising Information from various texts: A Study of Procedures and Products at Different Educational Levels. European Journal of Psychology of Education,  24 (4), 435-451. Available from https://doi.org/10.1007/BF03178760 [Accessed 29 June 2021].

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Literature Review Basics

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Synthesis: What is it?

First, let's be perfectly clear about what synthesizing your research isn't :

  • - It isn't  just summarizing the material you read
  • - It isn't  generating a collection of annotations or comments (like an annotated bibliography)
  • - It isn't  compiling a report on every single thing ever written in relation to your topic

When you  synthesize  your research, your job is to help your reader understand the current state of the conversation on your topic, relative to your research question.  That may include doing the following:

  • - Selecting and using representative work on the topic
  • - Identifying and discussing trends in published data or results
  • - Identifying and explaining the impact of common features (study populations, interventions, etc.) that appear frequently in the literature
  • - Explaining controversies, disputes, or central issues in the literature that are relevant to your research question
  • - Identifying gaps in the literature, where more research is needed
  • - Establishing the discussion to which your own research contributes and demonstrating the value of your contribution

Essentially, you're telling your reader where they are (and where you are) in the scholarly conversation about your project.

Synthesis: How do I do it?

Synthesis, step by step.

This is what you need to do  before  you write your review.

  • Identify and clearly describe your research question (you may find the Formulating PICOT Questions table at  the Additional Resources tab helpful).
  • Collect sources relevant to your research question.
  • Organize and describe the sources you've found -- your job is to identify what  types  of sources you've collected (reviews, clinical trials, etc.), identify their  purpose  (what are they measuring, testing, or trying to discover?), determine the  level of evidence  they represent (see the Levels of Evidence table at the Additional Resources tab ), and briefly explain their  major findings . Use a Research Table to document this step.
  • Study the information you've put in your Research Table and examine your collected sources, looking for  similarities  and  differences . Pay particular attention to  populations ,   methods  (especially relative to levels of evidence), and  findings .
  • Analyze what you learn in (4) using a tool like a Synthesis Table. Your goal is to identify relevant themes, trends, gaps, and issues in the research.  Your literature review will collect the results of this analysis and explain them in relation to your research question.

Analysis tips

  • - Sometimes, what you  don't  find in the literature is as important as what you do find -- look for questions that the existing research hasn't answered yet.
  • - If any of the sources you've collected refer to or respond to each other, keep an eye on how they're related -- it may provide a clue as to whether or not study results have been successfully replicated.
  • - Sorting your collected sources by level of evidence can provide valuable insight into how a particular topic has been covered, and it may help you to identify gaps worth addressing in your own work.
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What is Synthesis

What is Synthesis? Synthesis writing is a form of analysis related to comparison and contrast, classification and division. On a basic level, synthesis requires the writer to pull together two or more summaries, looking for themes in each text. In synthesis, you search for the links between various materials in order to make your point. Most advanced academic writing, including literature reviews, relies heavily on synthesis. (Temple University Writing Center)  

How To Synthesize Sources in a Literature Review

Literature reviews synthesize large amounts of information and present it in a coherent, organized fashion. In a literature review you will be combining material from several texts to create a new text – your literature review.

You will use common points among the sources you have gathered to help you synthesize the material. This will help ensure that your literature review is organized by subtopic, not by source. This means various authors' names can appear and reappear throughout the literature review, and each paragraph will mention several different authors. 

When you shift from writing summaries of the content of a source to synthesizing content from sources, there is a number things you must keep in mind: 

  • Look for specific connections and or links between your sources and how those relate to your thesis or question.
  • When writing and organizing your literature review be aware that your readers need to understand how and why the information from the different sources overlap.
  • Organize your literature review by the themes you find within your sources or themes you have identified. 
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Literature Reviews

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what is a synthesis of the literature

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In the synthesis step of a literature review, researchers analyze and integrate information from selected sources to identify patterns and themes. This involves critically evaluating findings, recognizing commonalities, and constructing a cohesive narrative that contributes to the understanding of the research topic.

Synthesis Not synthesis
✔️ Analyzing and integrating information ❌ Simply summarizing individual studies or articles
✔️ Identifying patterns and themes ❌ Listing facts without interpretation
✔️ Critically evaluating findings ❌ Copy-pasting content from sources
✔️ Constructing a cohesive narrative ❌ Providing personal opinions
✔️ Recognizing commonalities ❌ Focusing only on isolated details
✔️ Generating new perspectives ❌ Repeating information verbatim

Here are some examples of how to approach synthesizing the literature:

💡 By themes or concepts

🕘 Historically or chronologically

📊 By methodology

These organizational approaches can also be used when writing your review. It can be beneficial to begin organizing your references by these approaches in your citation manager by using folders, groups, or collections.

Create a synthesis matrix

A synthesis matrix allows you to visually organize your literature.

Topic: ______________________________________________

  Source #2 Source #3 Source #4
       
       

Topic: Chemical exposure to workers in nail salons

  Gutierrez et al. 2015 Hansen 2018 Lee et al. 2014
"Participants reported multiple episodes of asthma over one year" (p. 58)    
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Literature Synthesis

  • First Online: 31 August 2021

Cite this chapter

what is a synthesis of the literature

  • Ana Paula Cardoso Ermel   ORCID: orcid.org/0000-0002-3874-9792 5 ,
  • D. P. Lacerda   ORCID: orcid.org/0000-0002-8011-3376 6 ,
  • Maria Isabel W. M. Morandi   ORCID: orcid.org/0000-0003-1337-1487 7 &
  • Leandro Gauss   ORCID: orcid.org/0000-0001-5708-5912 8  

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  • The original version of this chapter was revised: Figure 5.1 was moved to section 5.2.9. The correction to this chapter can be found at https://doi.org/10.1007/978-3-030-75722-9_10

This chapter addresses the concept of Literature Synthesis and classifies it as Configurative and Aggregative based upon the research approach and objectives. For each type of synthesis, its main characteristics, techniques, and applications are pointed out.

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06 february 2022.

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Cardoso Ermel, A.P., Lacerda, D.P., Morandi, M.I.W.M., Gauss, L. (2021). Literature Synthesis. In: Literature Reviews. Springer, Cham. https://doi.org/10.1007/978-3-030-75722-9_5

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Literature Review Step by Step

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  • From University of North Carolina A clear verbal description of the literature review process.

What is Synthesis?

"The combination of components or elements to form a connected whole" (OED)

Forming a synthesis between various ideas is the heart of your literature review, and once done, will be the core of your research paper. As a starting point try:

• finding ideas that are common or controversial • two or three important trends in the research • the most influential theories.

As you read keep these questions in mind:

• does the writer make any assumptions not supported by evidence? • what is the researcher's method? how does she gather data? • what ideas and which researchers are frequently referred to?

Some writers of Literature Review create a matrix for organizing their research articles.

This requires you to come up with a number of categories which  grow out of your reading of the literature. As you read, write down ideas, words or controversies  that occur frequently. Ask yourself why? What question are these different papers trying to answer?

This process will generate a number of categories, You can use these to create a table. The article below offers more information on this method of organizing your process.

  • Creating a Matrix for Literature Review Synthesis
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  • Synthesizing Sources | Examples & Synthesis Matrix

Synthesizing Sources | Examples & Synthesis Matrix

Published on July 4, 2022 by Eoghan Ryan . Revised on May 31, 2023.

Synthesizing sources involves combining the work of other scholars to provide new insights. It’s a way of integrating sources that helps situate your work in relation to existing research.

Synthesizing sources involves more than just summarizing . You must emphasize how each source contributes to current debates, highlighting points of (dis)agreement and putting the sources in conversation with each other.

You might synthesize sources in your literature review to give an overview of the field or throughout your research paper when you want to position your work in relation to existing research.

Table of contents

Example of synthesizing sources, how to synthesize sources, synthesis matrix, other interesting articles, frequently asked questions about synthesizing sources.

Let’s take a look at an example where sources are not properly synthesized, and then see what can be done to improve it.

This paragraph provides no context for the information and does not explain the relationships between the sources described. It also doesn’t analyze the sources or consider gaps in existing research.

Research on the barriers to second language acquisition has primarily focused on age-related difficulties. Building on Lenneberg’s (1967) theory of a critical period of language acquisition, Johnson and Newport (1988) tested Lenneberg’s idea in the context of second language acquisition. Their research seemed to confirm that young learners acquire a second language more easily than older learners. Recent research has considered other potential barriers to language acquisition. Schepens, van Hout, and van der Slik (2022) have revealed that the difficulties of learning a second language at an older age are compounded by dissimilarity between a learner’s first language and the language they aim to acquire. Further research needs to be carried out to determine whether the difficulty faced by adult monoglot speakers is also faced by adults who acquired a second language during the “critical period.”

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To synthesize sources, group them around a specific theme or point of contention.

As you read sources, ask:

  • What questions or ideas recur? Do the sources focus on the same points, or do they look at the issue from different angles?
  • How does each source relate to others? Does it confirm or challenge the findings of past research?
  • Where do the sources agree or disagree?

Once you have a clear idea of how each source positions itself, put them in conversation with each other. Analyze and interpret their points of agreement and disagreement. This displays the relationships among sources and creates a sense of coherence.

Consider both implicit and explicit (dis)agreements. Whether one source specifically refutes another or just happens to come to different conclusions without specifically engaging with it, you can mention it in your synthesis either way.

Synthesize your sources using:

  • Topic sentences to introduce the relationship between the sources
  • Signal phrases to attribute ideas to their authors
  • Transition words and phrases to link together different ideas

To more easily determine the similarities and dissimilarities among your sources, you can create a visual representation of their main ideas with a synthesis matrix . This is a tool that you can use when researching and writing your paper, not a part of the final text.

In a synthesis matrix, each column represents one source, and each row represents a common theme or idea among the sources. In the relevant rows, fill in a short summary of how the source treats each theme or topic.

This helps you to clearly see the commonalities or points of divergence among your sources. You can then synthesize these sources in your work by explaining their relationship.

Example: Synthesis matrix
Lenneberg (1967) Johnson and Newport (1988) Schepens, van Hout, and van der Slik (2022)
Approach Primarily theoretical, due to the ethical implications of delaying the age at which humans are exposed to language Testing the English grammar proficiency of 46 native Korean or Chinese speakers who moved to the US between the ages of 3 and 39 (all participants had lived in the US for at least 3 years at the time of testing) Analyzing the results of 56,024 adult immigrants to the Netherlands from 50 different language backgrounds
Enabling factors in language acquisition A critical period between early infancy and puberty after which language acquisition capabilities decline A critical period (following Lenneberg) General age effects (outside of a contested critical period), as well as the similarity between a learner’s first language and target language
Barriers to language acquisition Aging Aging (following Lenneberg) Aging as well as the dissimilarity between a learner’s first language and target language

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Synthesizing sources means comparing and contrasting the work of other scholars to provide new insights.

It involves analyzing and interpreting the points of agreement and disagreement among sources.

You might synthesize sources in your literature review to give an overview of the field of research or throughout your paper when you want to contribute something new to existing research.

A literature review is a survey of scholarly sources (such as books, journal articles, and theses) related to a specific topic or research question .

It is often written as part of a thesis, dissertation , or research paper , in order to situate your work in relation to existing knowledge.

Topic sentences help keep your writing focused and guide the reader through your argument.

In an essay or paper , each paragraph should focus on a single idea. By stating the main idea in the topic sentence, you clarify what the paragraph is about for both yourself and your reader.

At college level, you must properly cite your sources in all essays , research papers , and other academic texts (except exams and in-class exercises).

Add a citation whenever you quote , paraphrase , or summarize information or ideas from a source. You should also give full source details in a bibliography or reference list at the end of your text.

The exact format of your citations depends on which citation style you are instructed to use. The most common styles are APA , MLA , and Chicago .

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Ryan, E. (2023, May 31). Synthesizing Sources | Examples & Synthesis Matrix. Scribbr. Retrieved August 12, 2024, from https://www.scribbr.com/working-with-sources/synthesizing-sources/

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Literature Reviews

  • Introduction
  • Tutorials and resources
  • Step 1: Literature search
  • Step 2: Analysis, synthesis, critique
  • Step 3: Writing the review

If you need any assistance, please contact the library staff at the Georgia Tech Library Help website . 

Analysis, synthesis, critique

Literature reviews build a story. You are telling the story about what you are researching. Therefore, a literature review is a handy way to show that you know what you are talking about. To do this, here are a few important skills you will need.

Skill #1: Analysis

Analysis means that you have carefully read a wide range of the literature on your topic and have understood the main themes, and identified how the literature relates to your own topic. Carefully read and analyze the articles you find in your search, and take notes. Notice the main point of the article, the methodologies used, what conclusions are reached, and what the main themes are. Most bibliographic management tools have capability to keep notes on each article you find, tag them with keywords, and organize into groups.

Skill #2: Synthesis

After you’ve read the literature, you will start to see some themes and categories emerge, some research trends to emerge, to see where scholars agree or disagree, and how works in your chosen field or discipline are related. One way to keep track of this is by using a Synthesis Matrix .

Skill #3: Critique

As you are writing your literature review, you will want to apply a critical eye to the literature you have evaluated and synthesized. Consider the strong arguments you will make contrasted with the potential gaps in previous research. The words that you choose to report your critiques of the literature will be non-neutral. For instance, using a word like “attempted” suggests that a researcher tried something but was not successful. For example: 

There were some attempts by Smith (2012) and Jones (2013) to integrate a new methodology in this process.

On the other hand, using a word like “proved” or a phrase like “produced results” evokes a more positive argument. For example:

The new methodologies employed by Blake (2014) produced results that provided further evidence of X.

In your critique, you can point out where you believe there is room for more coverage in a topic, or further exploration in in a sub-topic.

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Writing the Literature Review

  • Getting Started
  • Step 1: Choose A Topic
  • Step 2: Find Information
  • Step 3: Evaluate
  • Step 4: Take Notes
  • Step 5: Synthesize
  • Step 6: Stay Organized
  • Write the Review

Synthesizing

What is "Synthesis"?

what is a synthesis of the literature

Synthesis?  

Synthesis refers to combining separate elements to create a whole.  When reading through your sources (peer reviewed journal articles, books, research studies, white papers etc.) you will pay attention to relationships between the studies, between groups in the studies, and look for any pattterns,  similarities or differences.  Pay attention to methodologies, unexplored themes, and things that may represent a "gap" in the literature.  These "gaps" will be things you will want to be sure to identify in your literature review.  

  • Using a Synthesis Matrix to Plan a Literature Review Introduction to synthesis matrices, and explanation of the difference between synthesis and analysis. (Geared towards Health Science/ Nursing but applicable for other literature reviews) ***Includes a synthesis matrix example***
  • Using a Spider Diagram Organize your thoughts with a spider diagram

Ready, Set...Synthesize

  • Create an outline that puts your topics (and subtopics) into a logical order
  • Look at each subtopic that you have identified and determine what the articles in that group have in common with each other
  • Look at the articles in those subtopics that you have identified and look for areas where they differ.
  • If you spot findings that are contradictory, what differences do you think could account for those contradictions?  
  • Determine what general conclusions can be reported about that subtopic, and how it relates to the group of studies that you are discussing
  • As you write, remember to follow your outline, and use transitions as you move between topics 

Galvan, J. L. (2006). Writing literature reviews (3rd ed.). Glendale, CA: Pyrczak Publishing

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what is a synthesis of the literature

What is a Literature Review? How to Write It (with Examples)

literature review

A literature review is a critical analysis and synthesis of existing research on a particular topic. It provides an overview of the current state of knowledge, identifies gaps, and highlights key findings in the literature. 1 The purpose of a literature review is to situate your own research within the context of existing scholarship, demonstrating your understanding of the topic and showing how your work contributes to the ongoing conversation in the field. Learning how to write a literature review is a critical tool for successful research. Your ability to summarize and synthesize prior research pertaining to a certain topic demonstrates your grasp on the topic of study, and assists in the learning process. 

Table of Contents

  • What is the purpose of literature review? 
  • a. Habitat Loss and Species Extinction: 
  • b. Range Shifts and Phenological Changes: 
  • c. Ocean Acidification and Coral Reefs: 
  • d. Adaptive Strategies and Conservation Efforts: 

How to write a good literature review 

  • Choose a Topic and Define the Research Question: 
  • Decide on the Scope of Your Review: 
  • Select Databases for Searches: 
  • Conduct Searches and Keep Track: 
  • Review the Literature: 
  • Organize and Write Your Literature Review: 
  • How to write a literature review faster with Paperpal? 
  • Frequently asked questions 

What is a literature review?

A well-conducted literature review demonstrates the researcher’s familiarity with the existing literature, establishes the context for their own research, and contributes to scholarly conversations on the topic. One of the purposes of a literature review is also to help researchers avoid duplicating previous work and ensure that their research is informed by and builds upon the existing body of knowledge.

what is a synthesis of the literature

What is the purpose of literature review?

A literature review serves several important purposes within academic and research contexts. Here are some key objectives and functions of a literature review: 2  

1. Contextualizing the Research Problem: The literature review provides a background and context for the research problem under investigation. It helps to situate the study within the existing body of knowledge. 

2. Identifying Gaps in Knowledge: By identifying gaps, contradictions, or areas requiring further research, the researcher can shape the research question and justify the significance of the study. This is crucial for ensuring that the new research contributes something novel to the field. 

Find academic papers related to your research topic faster. Try Research on Paperpal  

3. Understanding Theoretical and Conceptual Frameworks: Literature reviews help researchers gain an understanding of the theoretical and conceptual frameworks used in previous studies. This aids in the development of a theoretical framework for the current research. 

4. Providing Methodological Insights: Another purpose of literature reviews is that it allows researchers to learn about the methodologies employed in previous studies. This can help in choosing appropriate research methods for the current study and avoiding pitfalls that others may have encountered. 

5. Establishing Credibility: A well-conducted literature review demonstrates the researcher’s familiarity with existing scholarship, establishing their credibility and expertise in the field. It also helps in building a solid foundation for the new research. 

6. Informing Hypotheses or Research Questions: The literature review guides the formulation of hypotheses or research questions by highlighting relevant findings and areas of uncertainty in existing literature. 

Literature review example

Let’s delve deeper with a literature review example: Let’s say your literature review is about the impact of climate change on biodiversity. You might format your literature review into sections such as the effects of climate change on habitat loss and species extinction, phenological changes, and marine biodiversity. Each section would then summarize and analyze relevant studies in those areas, highlighting key findings and identifying gaps in the research. The review would conclude by emphasizing the need for further research on specific aspects of the relationship between climate change and biodiversity. The following literature review template provides a glimpse into the recommended literature review structure and content, demonstrating how research findings are organized around specific themes within a broader topic. 

Literature Review on Climate Change Impacts on Biodiversity:

Climate change is a global phenomenon with far-reaching consequences, including significant impacts on biodiversity. This literature review synthesizes key findings from various studies: 

a. Habitat Loss and Species Extinction:

Climate change-induced alterations in temperature and precipitation patterns contribute to habitat loss, affecting numerous species (Thomas et al., 2004). The review discusses how these changes increase the risk of extinction, particularly for species with specific habitat requirements. 

b. Range Shifts and Phenological Changes:

Observations of range shifts and changes in the timing of biological events (phenology) are documented in response to changing climatic conditions (Parmesan & Yohe, 2003). These shifts affect ecosystems and may lead to mismatches between species and their resources. 

c. Ocean Acidification and Coral Reefs:

The review explores the impact of climate change on marine biodiversity, emphasizing ocean acidification’s threat to coral reefs (Hoegh-Guldberg et al., 2007). Changes in pH levels negatively affect coral calcification, disrupting the delicate balance of marine ecosystems. 

d. Adaptive Strategies and Conservation Efforts:

Recognizing the urgency of the situation, the literature review discusses various adaptive strategies adopted by species and conservation efforts aimed at mitigating the impacts of climate change on biodiversity (Hannah et al., 2007). It emphasizes the importance of interdisciplinary approaches for effective conservation planning. 

what is a synthesis of the literature

Strengthen your literature review with factual insights. Try Research on Paperpal for free!    

Writing a literature review involves summarizing and synthesizing existing research on a particular topic. A good literature review format should include the following elements. 

Introduction: The introduction sets the stage for your literature review, providing context and introducing the main focus of your review. 

  • Opening Statement: Begin with a general statement about the broader topic and its significance in the field. 
  • Scope and Purpose: Clearly define the scope of your literature review. Explain the specific research question or objective you aim to address. 
  • Organizational Framework: Briefly outline the structure of your literature review, indicating how you will categorize and discuss the existing research. 
  • Significance of the Study: Highlight why your literature review is important and how it contributes to the understanding of the chosen topic. 
  • Thesis Statement: Conclude the introduction with a concise thesis statement that outlines the main argument or perspective you will develop in the body of the literature review. 

Body: The body of the literature review is where you provide a comprehensive analysis of existing literature, grouping studies based on themes, methodologies, or other relevant criteria. 

  • Organize by Theme or Concept: Group studies that share common themes, concepts, or methodologies. Discuss each theme or concept in detail, summarizing key findings and identifying gaps or areas of disagreement. 
  • Critical Analysis: Evaluate the strengths and weaknesses of each study. Discuss the methodologies used, the quality of evidence, and the overall contribution of each work to the understanding of the topic. 
  • Synthesis of Findings: Synthesize the information from different studies to highlight trends, patterns, or areas of consensus in the literature. 
  • Identification of Gaps: Discuss any gaps or limitations in the existing research and explain how your review contributes to filling these gaps. 
  • Transition between Sections: Provide smooth transitions between different themes or concepts to maintain the flow of your literature review. 

Write and Cite as you go with Paperpal Research. Start now for free.   

Conclusion: The conclusion of your literature review should summarize the main findings, highlight the contributions of the review, and suggest avenues for future research. 

  • Summary of Key Findings: Recap the main findings from the literature and restate how they contribute to your research question or objective. 
  • Contributions to the Field: Discuss the overall contribution of your literature review to the existing knowledge in the field. 
  • Implications and Applications: Explore the practical implications of the findings and suggest how they might impact future research or practice. 
  • Recommendations for Future Research: Identify areas that require further investigation and propose potential directions for future research in the field. 
  • Final Thoughts: Conclude with a final reflection on the importance of your literature review and its relevance to the broader academic community. 

what is a literature review

Conducting a literature review

Conducting a literature review is an essential step in research that involves reviewing and analyzing existing literature on a specific topic. It’s important to know how to do a literature review effectively, so here are the steps to follow: 1  

Choose a Topic and Define the Research Question:

  • Select a topic that is relevant to your field of study. 
  • Clearly define your research question or objective. Determine what specific aspect of the topic do you want to explore? 

Decide on the Scope of Your Review:

  • Determine the timeframe for your literature review. Are you focusing on recent developments, or do you want a historical overview? 
  • Consider the geographical scope. Is your review global, or are you focusing on a specific region? 
  • Define the inclusion and exclusion criteria. What types of sources will you include? Are there specific types of studies or publications you will exclude? 

Select Databases for Searches:

  • Identify relevant databases for your field. Examples include PubMed, IEEE Xplore, Scopus, Web of Science, and Google Scholar. 
  • Consider searching in library catalogs, institutional repositories, and specialized databases related to your topic. 

Conduct Searches and Keep Track:

  • Develop a systematic search strategy using keywords, Boolean operators (AND, OR, NOT), and other search techniques. 
  • Record and document your search strategy for transparency and replicability. 
  • Keep track of the articles, including publication details, abstracts, and links. Use citation management tools like EndNote, Zotero, or Mendeley to organize your references. 

Review the Literature:

  • Evaluate the relevance and quality of each source. Consider the methodology, sample size, and results of studies. 
  • Organize the literature by themes or key concepts. Identify patterns, trends, and gaps in the existing research. 
  • Summarize key findings and arguments from each source. Compare and contrast different perspectives. 
  • Identify areas where there is a consensus in the literature and where there are conflicting opinions. 
  • Provide critical analysis and synthesis of the literature. What are the strengths and weaknesses of existing research? 

Organize and Write Your Literature Review:

  • Literature review outline should be based on themes, chronological order, or methodological approaches. 
  • Write a clear and coherent narrative that synthesizes the information gathered. 
  • Use proper citations for each source and ensure consistency in your citation style (APA, MLA, Chicago, etc.). 
  • Conclude your literature review by summarizing key findings, identifying gaps, and suggesting areas for future research. 

Whether you’re exploring a new research field or finding new angles to develop an existing topic, sifting through hundreds of papers can take more time than you have to spare. But what if you could find science-backed insights with verified citations in seconds? That’s the power of Paperpal’s new Research feature!  

How to write a literature review faster with Paperpal?

Paperpal, an AI writing assistant, integrates powerful academic search capabilities within its writing platform. With the Research feature, you get 100% factual insights, with citations backed by 250M+ verified research articles, directly within your writing interface with the option to save relevant references in your Citation Library. By eliminating the need to switch tabs to find answers to all your research questions, Paperpal saves time and helps you stay focused on your writing.   

Here’s how to use the Research feature:  

  • Ask a question: Get started with a new document on paperpal.com. Click on the “Research” feature and type your question in plain English. Paperpal will scour over 250 million research articles, including conference papers and preprints, to provide you with accurate insights and citations. 
  • Review and Save: Paperpal summarizes the information, while citing sources and listing relevant reads. You can quickly scan the results to identify relevant references and save these directly to your built-in citations library for later access. 
  • Cite with Confidence: Paperpal makes it easy to incorporate relevant citations and references into your writing, ensuring your arguments are well-supported by credible sources. This translates to a polished, well-researched literature review. 

The literature review sample and detailed advice on writing and conducting a review will help you produce a well-structured report. But remember that a good literature review is an ongoing process, and it may be necessary to revisit and update it as your research progresses. By combining effortless research with an easy citation process, Paperpal Research streamlines the literature review process and empowers you to write faster and with more confidence. Try Paperpal Research now and see for yourself.  

Frequently asked questions

A literature review is a critical and comprehensive analysis of existing literature (published and unpublished works) on a specific topic or research question and provides a synthesis of the current state of knowledge in a particular field. A well-conducted literature review is crucial for researchers to build upon existing knowledge, avoid duplication of efforts, and contribute to the advancement of their field. It also helps researchers situate their work within a broader context and facilitates the development of a sound theoretical and conceptual framework for their studies.

Literature review is a crucial component of research writing, providing a solid background for a research paper’s investigation. The aim is to keep professionals up to date by providing an understanding of ongoing developments within a specific field, including research methods, and experimental techniques used in that field, and present that knowledge in the form of a written report. Also, the depth and breadth of the literature review emphasizes the credibility of the scholar in his or her field.  

Before writing a literature review, it’s essential to undertake several preparatory steps to ensure that your review is well-researched, organized, and focused. This includes choosing a topic of general interest to you and doing exploratory research on that topic, writing an annotated bibliography, and noting major points, especially those that relate to the position you have taken on the topic. 

Literature reviews and academic research papers are essential components of scholarly work but serve different purposes within the academic realm. 3 A literature review aims to provide a foundation for understanding the current state of research on a particular topic, identify gaps or controversies, and lay the groundwork for future research. Therefore, it draws heavily from existing academic sources, including books, journal articles, and other scholarly publications. In contrast, an academic research paper aims to present new knowledge, contribute to the academic discourse, and advance the understanding of a specific research question. Therefore, it involves a mix of existing literature (in the introduction and literature review sections) and original data or findings obtained through research methods. 

Literature reviews are essential components of academic and research papers, and various strategies can be employed to conduct them effectively. If you want to know how to write a literature review for a research paper, here are four common approaches that are often used by researchers.  Chronological Review: This strategy involves organizing the literature based on the chronological order of publication. It helps to trace the development of a topic over time, showing how ideas, theories, and research have evolved.  Thematic Review: Thematic reviews focus on identifying and analyzing themes or topics that cut across different studies. Instead of organizing the literature chronologically, it is grouped by key themes or concepts, allowing for a comprehensive exploration of various aspects of the topic.  Methodological Review: This strategy involves organizing the literature based on the research methods employed in different studies. It helps to highlight the strengths and weaknesses of various methodologies and allows the reader to evaluate the reliability and validity of the research findings.  Theoretical Review: A theoretical review examines the literature based on the theoretical frameworks used in different studies. This approach helps to identify the key theories that have been applied to the topic and assess their contributions to the understanding of the subject.  It’s important to note that these strategies are not mutually exclusive, and a literature review may combine elements of more than one approach. The choice of strategy depends on the research question, the nature of the literature available, and the goals of the review. Additionally, other strategies, such as integrative reviews or systematic reviews, may be employed depending on the specific requirements of the research.

The literature review format can vary depending on the specific publication guidelines. However, there are some common elements and structures that are often followed. Here is a general guideline for the format of a literature review:  Introduction:   Provide an overview of the topic.  Define the scope and purpose of the literature review.  State the research question or objective.  Body:   Organize the literature by themes, concepts, or chronology.  Critically analyze and evaluate each source.  Discuss the strengths and weaknesses of the studies.  Highlight any methodological limitations or biases.  Identify patterns, connections, or contradictions in the existing research.  Conclusion:   Summarize the key points discussed in the literature review.  Highlight the research gap.  Address the research question or objective stated in the introduction.  Highlight the contributions of the review and suggest directions for future research.

Both annotated bibliographies and literature reviews involve the examination of scholarly sources. While annotated bibliographies focus on individual sources with brief annotations, literature reviews provide a more in-depth, integrated, and comprehensive analysis of existing literature on a specific topic. The key differences are as follows: 

 Annotated Bibliography Literature Review 
Purpose List of citations of books, articles, and other sources with a brief description (annotation) of each source. Comprehensive and critical analysis of existing literature on a specific topic. 
Focus Summary and evaluation of each source, including its relevance, methodology, and key findings. Provides an overview of the current state of knowledge on a particular subject and identifies gaps, trends, and patterns in existing literature. 
Structure Each citation is followed by a concise paragraph (annotation) that describes the source’s content, methodology, and its contribution to the topic. The literature review is organized thematically or chronologically and involves a synthesis of the findings from different sources to build a narrative or argument. 
Length Typically 100-200 words Length of literature review ranges from a few pages to several chapters 
Independence Each source is treated separately, with less emphasis on synthesizing the information across sources. The writer synthesizes information from multiple sources to present a cohesive overview of the topic. 

References 

  • Denney, A. S., & Tewksbury, R. (2013). How to write a literature review.  Journal of criminal justice education ,  24 (2), 218-234. 
  • Pan, M. L. (2016).  Preparing literature reviews: Qualitative and quantitative approaches . Taylor & Francis. 
  • Cantero, C. (2019). How to write a literature review.  San José State University Writing Center . 

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  • Empirical Research: A Comprehensive Guide for Academics 
  • How to Write a Scientific Paper in 10 Steps 
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Synthetic literature reviews: An introduction

By Steve Wallis and Bernadette Wright 26/05/2020

Whether you are writing a funding proposal or an academic paper, you will most likely be required to start with a literature review of some kind. Despite (or because of) the work involved, a literature review is a great opportunity to showcase your knowledge on a topic. In this post, we’re going to take it one step further. We’re going to tell you a very practical approach to conducting literature reviews that allows you to show that you are advancing scientific knowledge before your project even begins. Also – and this is no small bonus – this approach lets you show how your literature review will lead to a more successful project.

Literature review – start with the basics

A literature review helps you shape effective solutions to the problems you (and your organisation) are facing. A literature review also helps you demonstrate the value of your activities. You can show how much you add to the process before you spend any money collecting new data. Finally, your literature review helps you avoid reinventing the wheel by showing you what relevant research already exists, so that you can target your new research more efficiently and more effectively.

We all want to conduct good research and have a meaningful impact on people’s lives. To do this, a literature review is a critical step. For funders, a literature review is especially important because it shows how much useful knowledge the writer already has.

Past methods of literature reviews tend to be focused on ‘muscle power’, that is spending more time and more effort to review more papers and adhering more closely to accepted standards. Examples of standards for conducting literature reviews include the PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions and the guidelines for assessing the quality and applicability of systematic reviews developed by the Task Force on Systematic Review and Guidelines . Given the untold millions of papers in many disciplines, even a large literature review that adheres to the best guidelines does little to move us toward integrated knowledge in and across disciplines.

In short, we need we need to work smarter, not harder!

Synthetic literature reviews

One approach that can provide more benefit is the synthetic literature review. Synthetic meaning synthesised or integrated, not artificial. Rather than explaining and reflecting on the results of previous studies (as is typically done in literature reviews), a synthetic literature review strives to create a new and more useful theoretical perspective by rigorously integrating the results of previous studies.

Many people find the process of synthesis difficult, elusive, or mysterious. When presenting their views and making recommendations for research, they tend to fall back on intuition (which is neither harder nor smarter).

After defining your research topic (‘poverty’ for example), the next step is to search the literature for existing theories or models of poverty that have been developed from research. You can use Google Scholar or your institutional database, or the assistance of a research librarian. A broad topic such as ‘poverty’, however, will lead you to millions of articles. You’ll narrow that field by focusing more closely on your topic and adding search terms. For example, you might be more interested in poverty among Latino communities in central California. You might also focus your search according to the date of the study (often, but not always, more recent results are preferred), or by geographic location. Continue refining and focusing your search until you have a workable number of papers (depending on your available time and resources). You might also take this time to throw out the papers that seem to be less relevant.

Skim those papers to be sure that they are really relevant to your topic. Once you have chosen a workable number of relevant papers, it is time to start integrating them.

Next, sort them according to the quality of their data.

Next, read the theory presented in each paper and create a diagram of the theory. The theory may be found in a section called ‘theory’ or sometimes in the ‘introduction’. For research papers, that presented theory may have changed during the research process, so you should look for the theory in the ‘findings’, ‘results’, or ‘discussion’ sections.

That diagram should include all relevant concepts from the theory and show the causal connections between the concepts that have been supported by research (some papers will present two theories, one before and one after the research – use the second one – only the hypotheses that have been supported by the research).

For a couple of brief and partial example from a recent interdisciplinary research paper, one theory of poverty might say ‘Having more education will help people to stay out of poverty’, while another might say ‘The more that the economy develops, the less poverty there will be’.

We then use those statements to create a diagram as we have in Figure 1.

what is a synthesis of the literature

Figure 1. Two (simple, partial) theories of poverty. (We like to use dashed lines to indicate ’causes less’, and solid lines to indicate ’causes more’)

When you have completed a diagram for each theory, the next step is to synthesise (integrate) them where the concepts are the same (or substantively similar) between two or more theories. With causal diagrams such as these, the process of synthesis becomes pretty direct. We simply combine the two (or more) theories to create a synthesised theory, such as in Figure 2.

what is a synthesis of the literature

Figure 2. Two theories synthesised where they overlap (in this case theories of poverty)

Much like a road map, a causal diagram of a theory with more concepts and more connecting arrows is more useful for navigation. You can show that your literature review is better than previous reviews by showing that you have taken a number of fragmented theories (as in Figure 1) and synthesised them to create a more coherent theory (as in Figure 2).

To go a step further, you may use Integrative Propositional Analysis (IPA) to quantify the extent to which your research has improved the structure and potential usefulness of your knowledge through the synthesis. Another source is our new book from Practical Mapping for Applied Research and Program Evaluation (see especially Chapter 5). (For the basics, you can look at Chapter One for free on the publisher’s site by clicking on the ‘Preview’ tab here. )

Once you become comfortable with the process, you will certainly be working ‘smarter’ and showcasing your knowledge to funders!

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How to Synthesise Sources – Steps and Examples

Published by Olive Robin at October 17th, 2023 , Revised On October 17, 2023

The ability to effectively incorporate multiple sources into one’s work is not just a skill, but a necessity. Whether we are talking about research papers, articles, or even simple blog posts, synthesising sources can elevate our content to a more nuanced, comprehensive, and insightful level. But what does it truly mean to synthesise sources, and how does it differ from the commonly understood techniques of summarising and paraphrasing?

Importance of Synthesising Sources in Research and Writing

When finding sources , it is imperative to distinguish between various available information types. Secondary sources , for example, provide interpretations and analyses based on primary sources. Synthesising goes beyond the mere gathering of information. It involves the complex task of interweaving multiple sources to generate a broader and richer perspective. When we synthesise, we are not just collecting; we are connecting. 

By merging various viewpoints and data, we provide our readers with a well-rounded understanding of the topic. This approach ensures that our work is grounded in credible sources  while also adding unique insights.

Summarising, Paraphrasing, and Synthesising

At first glance, these three techniques might seem similar, but they serve distinctly different purposes:

Summarising

Synthesis is the art of blending multiple sources to create a unified narrative or argument. It is essential to use signal phrases to introduce these sources naturally, helping the reader follow the information flow. Block quotes can also be used for direct quotations, especially if they’re longer.

Paraphrasing

Here, we restate the original content using different words. While the wording changes, the essence and core meaning remain intact. This method is useful for clarifying complex ideas or for tailoring content to a specific audience.

Synthesising

Synthesis is the art of blending multiple sources to create a unified narrative or argument. It is not about echoing what others have said; it is about drawing connections, identifying patterns, and building a cohesive piece that holds its own merit.

What is Synthesising Sources?

Synthesising sources is a method used in research and writing wherein the author combines, interprets, and analyses information from various sources to generate a unified perspective, narrative, or argument. It involves a process that we can call source evaluation . It is an intricate process that goes beyond simply collecting data or quoting authors. Instead, it involves evaluating, integrating, and constructing a new narrative based on a collective understanding of all the sources under consideration.

Imagine a quilt where each piece of fabric represents a different source. Synthesising would be the act of sewing these individual pieces together in such a way that they form a beautiful, cohesive blanket. Each piece retains its uniqueness but contributes to the larger design and purpose of the quilt.

Objective of Synthesising

  • Synthesising allows writers to delve deeper into topics by using a multitude of perspectives. This offers a more robust and comprehensive view than any single source could provide.
  • By integrating diverse sources, authors can identify trends, consistencies, or discrepancies within a field or topic. This can lead to new insights or highlight areas needing further exploration.
  • By interlinking sources, writers can add layers of complexity to their arguments, making their content more engaging and thought-provoking.
  • While the sources themselves might not be new, the way in which they are combined and interpreted can lead to fresh conclusions and unique standpoints.
  • Relying on a single source or a few like-minded ones can inadvertently introduce biases. Synthesising encourages the consideration of diverse viewpoints, ensuring a more balanced representation of the topic.

Why is Synthesis Important?

The art of synthesis, while a nuanced aspect of research and writing, holds unparalleled significance in constructing meaningful, in-depth content. Here is a detailed exploration of why synthesis is pivotal:

Enhancing Comprehension and Knowledge Depth

  • Depth Over Breadth: While a vast amount of information exists on nearly any topic, true understanding isn’t about skimming the surface. Synthesising allows you to dive deeper, connecting various pieces of information and seeing the bigger picture.
  • Clarifying Complexity: Topics, especially those in research, can be multifaceted. By merging multiple sources, we can simplify and explain intricate subjects more effectively.
  • Reinforcing Concepts: By revisiting a concept from various sources and angles, the repetition, in a way, strengthens our grasp on the subject. It’s like studying from multiple textbooks; the overlap in content solidifies understanding.

Avoiding Plagiarism

  • Original Thought Generation: While synthesising, you are compelled to merge ideas, compare viewpoints, and draw unique conclusions. This process naturally leads to producing original content rather than merely reproducing what one source says.
  • Skilful Integration: A well-synthesised piece does not heavily rely on long, verbatim quotes. Instead, it seamlessly integrates information from various sources, duly cited, minimising the chances of unintentional plagiarism.
  • Reflecting Authentic Engagement: When you synthesise, it showcases your genuine engagement with the material. It’s evident that you have not just copied content but have wrestled with the information, pondered upon it, and made it your own.

Developing a Holistic Perspective on a Topic

  • Seeing the Full Spectrum: Single sources can offer a limited or biased viewpoint. Synthesis, by its nature, compels you to consult multiple sources, allowing for a more balanced and comprehensive view.
  • Connecting the Dots: Life, society, and most academic subjects are interconnected. Synthesis helps recognise patterns, draw parallels, and understand how various elements interplay in the grand scheme of things.
  • Elevating Critical Thinking: The act of synthesis hones your critical thinking skills. You’re constantly evaluating the validity of sources, comparing arguments, and discerning the weight of different perspectives. This makes your current work stronger and sharpens your intellect for future projects.

Steps of Synthesizing a Source

Here is a step-by-step guide on how to synthesise sources. 

Step 1: Read and Understand

Before you can synthesise sources effectively, you must first understand them individually. A strong synthesis is built upon a clear understanding of each source’s content, context, and nuances.

Tips To Ensure Comprehension

  • Annotations: Make notes in the margins as you read, highlighting key points and ideas.
  • Summarisation: After reading a section or an article, write a brief summary in your own words.
  • Discussion: Talk about the content with peers or mentors. This can help clarify any confusion and deepen your understanding.
  • Questioning: Constantly ask questions as you read. If something is unclear, revisit the content or consult supplementary materials.

Step 2: Identify Common Themes

Sources will often touch upon similar themes, even if they approach them differently. Recognising these themes can act as a foundation for synthesis.

  • Mind Mapping: Visualise the interconnectedness of topics and subtopics.
  • Lists: Create lists of similar ideas or arguments from different sources.
  • Highlighting: Use colour codes to highlight recurring themes across different documents.

Step 3: Analyse and Compare

Different sources might have diverging opinions or findings. Recognising these differences is crucial to produce a balanced synthesis.

  • Side-by-Side Analysis: Put the information from various sources next to each other to see how they align or diverge.
  • Critical Evaluation: Ask yourself why sources might have different perspectives. Consider the methodology, context, or biases that could contribute.

Determining the Relevance of Each Source

Not all sources will hold equal weight or relevance in your synthesis.

  • Criteria Checklist: Establish criteria for relevance (e.g., publication date, author credentials) and evaluate each source against this.
  • Priority Setting: Decide which sources offer primary insights and which offer supplementary information.

Step 4: Organise Information

A clear structure is essential to guide your readers through the synthesised narrative.

  • Outlines: Create a traditional outline that sequences your main points and supports them with subpoints from your sources.
  • Flowcharts: For more complex topics, flowcharts can visually demonstrate the progression of ideas and their interconnections.

Step 5: Craft Your Narrative

This step involves the actual writing, where you combine the insights, evidence, and analysis into a singular narrative.

  • Transitional Phrasing: Use transitions to move between ideas and sources smoothly.
  • Voice Consistency: Even though you integrate multiple sources, ensure that the narrative maintains a consistent voice and tone.

Step 6: Cite Appropriately

Always credit original authors and sources to maintain integrity in your work and avoid plagiarism. Knowing how to cite sources is crucial in this process.

  • In-text Citations: Whenever you refer to, paraphrase, or quote a source, provide a citation.

Different Citation Styles and Choosing The Right One

There are multiple citation styles (e.g., APA, MLA, Chicago), and your choice will often depend on your discipline or the preference of your institution or publication.

  • Guideline Review: Familiarise yourself with the preferred citation style’s guidelines.

Citation Tools: Consider using tools like Zotero, Mendeley, or EndNote to help streamline and manage your citations.

The research done by our experts have:

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what is a synthesis of the literature

Examples of Source Synthesis

Let’s explore some examples of synthesising sources. 

Example 1: Synthesising sources on climate change

Scenario: You have sources that discuss the causes of climate change. Some sources argue for anthropogenic (human-caused) factors, while others emphasise natural cycles.

Synthesis Approach

  • Begin with an overview of climate change, its impacts, and its significance.
  • Introduce the anthropogenic viewpoint, citing research on the rise of CO2 from industrial processes, deforestation, etc.
  • Present the natural cycle perspective, highlighting periods in Earth’s history where temperature fluctuations were observed.
  • Discuss overlaps, such as how human activities might exacerbate natural cycles.
  • Conclude by emphasising the consensus in the scientific community about human contributions to recent climate change, but acknowledge the existence of natural cycles as part of Earth’s climate history.

Example 2: Merging Historical Texts on a Particular Event

Scenario: You are examining the Battle of Waterloo from British, French, and Prussian primary sources.

  • Provide background on the Battle of Waterloo, setting the stage.
  • Introduce the British perspective, detailing their strategies, key figures, and their account of the battle’s progression.
  • Shift to the French viewpoint, noting their strategic decisions, challenges, and Napoleon’s role.
  • Explore the Prussian account, emphasising their contributions and coordination with the British.
  • Highlight areas of agreement among the sources (e.g., timeline of events) and areas of discrepancy or unique insights (e.g., differing reasons for the outcome).
  • Conclude with a comprehensive view of the battle, incorporating insights from all perspectives and its significance in European history.

Example 3: Synthesising Qualitative And Quantitative Research On A Social Issue

Scenario: You are researching the effects of remote learning on student performance and well-being during the pandemic.

  • Start with an introduction to the sudden shift to remote learning due to COVID-19.
  • Present quantitative data: statistics showcasing the drop or rise in student grades, attendance rates, and standardised test scores.
  • Introduce qualitative insights, like interviews or case studies, highlighting student sentiments, challenges faced at home, or feelings of isolation.
  • Discuss the interplay between numbers and narratives. For instance, a drop in grades (quantitative) could be related to a lack of motivation or home distractions (qualitative).
  • Compare outcomes across different demographics, using both types of data to show how remote learning might affect diverse student populations differently.
  • Conclude with a holistic understanding of the impacts of remote learning, noting areas that need further research or intervention.

Common Mistakes to Avoid when Synthesising Sources

  • Relying heavily on a single source limits the depth and breadth of your understanding. It may also inadvertently introduce bias if that source isn’t comprehensive or neutral.
  • How to Avoid: Ensure you consult various sources for a well-rounded view. This includes both primary and secondary sources, academic articles, and more accessible pieces like news articles or blogs, if relevant.
  • Every source comes with its own perspective. Identifying these biases can lead to a skewed understanding of your topic.
  • How to Avoid: Critical reading is key. Always consider who the author is, their potential motivations, the context in which they’re writing, and the methodologies they use.
  • Simply presenting what each source says without drawing connections or highlighting contrasts misses the essence of synthesis.
  • How to Avoid: As you research, actively look for common themes, conflicting viewpoints, and unique insights. Your goal is to weave a narrative that reflects a comprehensive understanding of all these elements.

Tools and Resources for Synthesising Sources

These are the different tools that can be used for synthesising sources. 

Citation Tools

Managing references can be cumbersome, especially when dealing with numerous sources. Citation tools can help organise, format, and insert citations with ease.

  • Zotero: A free, open-source tool that helps you collect, organise, cite, and share research.
  • Mendeley: A reference manager and academic social network that can help you organise your research, collaborate with others online, and discover the latest developments.

Mind-Mapping Software or Apps

Mind mapping helps visually organise and interlink ideas, making the synthesis process more intuitive.

  • MindMeister: An online mind-mapping tool that lets you capture, develop, and share ideas visually.
  • XMind: A popular mind mapping and brainstorming software with various templates to help structure your thoughts.

Note-Taking Apps and Strategies

Effective note-taking is fundamental to understanding and organising information from various sources. Digital note-taking apps often offer features like tagging, search functionalities, and integration with other tools.

  • Evernote: A cross-platform app designed for note-taking, organising, and archiving.
  • Microsoft OneNote: A digital notebook that allows you to gather drawings, handwritten or typed notes, and save web clippings.
  • Cornell Note-taking System: A structured method of note-taking that divides the paper into sections, encouraging active engagement with the material.

Frequently Asked Questions

What is a literature review.

A literature review is a comprehensive survey of existing research on a particular topic, synthesising findings to provide an overview of key concepts, debates, and gaps in knowledge. It establishes a foundation for new research, highlighting relevant studies and contextualising them within the broader academic conversation.

How to synthesise a source?

To synthesise a source, thoroughly understand its content, and then integrate its insights with information from other sources. This involves comparing and contrasting viewpoints, identifying patterns, and constructing a cohesive narrative or argument that offers a broader perspective rather than merely echoing the original source’s content.

Why do I need to cite sources?

Citing sources acknowledges original authors, maintains academic integrity, and provides readers with a reference for verification. It prevents plagiarism by giving credit to the ideas and research of others, allowing readers to trace the evolution of thought and confirm the reliability and accuracy of the presented information.

What are topic sentences?

Topic sentences are the main statements that introduce and summarise a paragraph’s main idea or focus. They provide context and direction, helping readers follow the writer’s argument or narrative. Typically placed at the beginning of a paragraph, they act as signposts, guiding the flow of the discussion.

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Primary sources refer to original, unmediated documents or records that have not been altered or transformed by interpretation or commentary. They provide first-hand accounts, evidence, or direct testimony concerning a subject or event under investigation.

In the digital age, where information is abundant and readily accessible, quickly finding precise and relevant information is paramount. This is where Boolean operators come into play. 

Information literacy is more than just the ability to find information; it encompasses the skills to recognise when information is needed and the competence to locate, evaluate, use, and ethically disseminate it.

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A Guide to Evidence Synthesis: What is Evidence Synthesis?

  • Meet Our Team
  • Our Published Reviews and Protocols
  • What is Evidence Synthesis?
  • Types of Evidence Synthesis
  • Evidence Synthesis Across Disciplines
  • Finding and Appraising Existing Systematic Reviews
  • 0. Develop a Protocol
  • 1. Draft your Research Question
  • 2. Select Databases
  • 3. Select Grey Literature Sources
  • 4. Write a Search Strategy
  • 5. Register a Protocol
  • 6. Translate Search Strategies
  • 7. Citation Management
  • 8. Article Screening
  • 9. Risk of Bias Assessment
  • 10. Data Extraction
  • 11. Synthesize, Map, or Describe the Results
  • Evidence Synthesis Institute for Librarians
  • Open Access Evidence Synthesis Resources

What are Evidence Syntheses?

What are evidence syntheses.

According to the Royal Society, 'evidence synthesis' refers to the process of bringing together information from a range of sources and disciplines to inform debates and decisions on specific issues. They generally include a methodical and comprehensive literature synthesis focused on a well-formulated research question.  Their aim is to identify and synthesize all  of the scholarly research on a particular topic, including both published and unpublished studies. Evidence syntheses are conducted in an unbiased, reproducible way to provide evidence for practice and policy-making, as well as to identify gaps in the research. Evidence syntheses may also include a meta-analysis, a more quantitative process of synthesizing and visualizing data retrieved from various studies. 

Evidence syntheses are much more time-intensive than traditional literature reviews and require a multi-person research team. See this PredicTER tool to get a sense of a systematic review timeline (one type of evidence synthesis). Before embarking on an evidence synthesis, it's important to clearly identify your reasons for conducting one. For a list of types of evidence synthesis projects, see the next tab.

How Does a Traditional Literature Review Differ From an Evidence Synthesis?

How does a systematic review differ from a traditional literature review.

One commonly used form of evidence synthesis is a systematic review.  This table compares a traditional literature review with a systematic review.

 

Review Question/Topic

Topics may be broad in scope; the goal of the review may be to place one's own research within the existing body of knowledge, or to gather information that supports a particular viewpoint.

Starts with a well-defined research question to be answered by the review. Reviews are conducted with the aim of finding all existing evidence in an unbiased, transparent, and reproducible way.

Searching for Studies

Searches may be ad hoc and based on what the author is already familiar with. Searches are not exhaustive or fully comprehensive.

Attempts are made to find all existing published and unpublished literature on the research question. The process is well-documented and reported.

Study Selection

Often lack clear reasons for why studies were included or excluded from the review.

Reasons for including or excluding studies are explicit and informed by the research question.

Assessing the Quality of Included Studies

Often do not consider study quality or potential biases in study design.

Systematically assesses risk of bias of individual studies and overall quality of the evidence, including sources of heterogeneity between study results.

Synthesis of Existing Research

Conclusions are more qualitative and may not be based on study quality.

Bases conclusion on quality of the studies and provide recommendations for practice or to address knowledge gaps.

Video: Reproducibility and transparent methods (Video 3:25)

Reporting Standards

There are some reporting standards for evidence syntheses. These can serve as guidelines for protocol and manuscript preparation and journals may require that these standards are followed for the review type that is being employed (e.g. systematic review, scoping review, etc). ​

  • PRISMA checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) is an evidence-based minimum set of items for reporting in systematic reviews and meta-analyses.
  • PRISMA-P Standards An updated version of the original PRISMA standards for protocol development.
  • PRISMA - ScR Reporting guidelines for scoping reviews and evidence maps
  • PRISMA-IPD Standards Extension of the original PRISMA standards for systematic reviews and meta-analyses of individual participant data.
  • EQUATOR Network The EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network is an international initiative that seeks to improve the reliability and value of published health research literature by promoting transparent and accurate reporting and wider use of robust reporting guidelines. They provide a list of various standards for reporting in systematic reviews.

Video: Guidelines and reporting standards

PRISMA Flow Diagram

The  PRISMA  flow diagram depicts the flow of information through the different phases of an evidence synthesis. It maps the search (number of records identified), screening (number of records included and excluded), and selection (reasons for exclusion).  Many evidence syntheses include a PRISMA flow diagram in the published manuscript.

See below for resources to help you generate your own PRISMA flow diagram.

  • PRISMA Flow Diagram Tool
  • PRISMA Flow Diagram Word Template
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  • 1. Develop a Protocol
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  • 3. Select Databases
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  • 11. Data Extraction
  • 12. Synthesize, Map, or Describe the Results
  • Evidence Synthesis Resources & Tools

What are evidence syntheses?

According to the Royal Society, 'evidence synthesis' refers to the process of bringing together information from a range of sources and disciplines to inform debates and decisions on specific issues. They generally include a methodical and comprehensive literature synthesis focused on a well-formulated research question. Their aim is to identify and synthesize all of the scholarly research on a particular topic, including both published and unpublished studies. Evidence syntheses are conducted in an unbiased, reproducible way to provide evidence for practice and policy-making, as well as to identify gaps in the research. Evidence syntheses may also include a meta-analysis, a more quantitative process of synthesizing and visualizing data retrieved from various studies.

Evidence syntheses are much more time-intensive than traditional literature reviews and require a multi-person research team. See this PredicTER tool to get a sense of a systematic review timeline (one type of evidence synthesis). Before embarking on an evidence synthesis, it's important to clearly identify your reasons for conducting one. For a list of types of evidence synthesis projects, see the Types of Evidence Synthesis tab.

How does a traditional literature review differ from evidence synthesis?

One commonly used form of evidence synthesis is a systematic review. This table compares a traditional literature review with a systematic review.

 

Review Question/Topic

Topics may be broad in scope; the goal of the review may be to place one's own research within the existing body of knowledge, or to gather information that supports a particular viewpoint.

Starts with a well-defined research question to be answered by the review. Reviews are conducted with the aim of finding all existing evidence in an unbiased, transparent, and reproducible way.

Searching for Studies

Searches may be ad hoc and based on what the author is already familiar with. Searches are not exhaustive or fully comprehensive.

Attempts are made to find all existing published and unpublished literature on the research question. The process is well-documented and reported.

Study Selection

Often lack clear reasons for why studies were included or excluded from the review.

Reasons for including or excluding studies are explicit and informed by the research question.

Assessing the Quality of Included Studies

Often do not consider study quality or potential biases in study design.

Systematically assesses risk of bias of individual studies and overall quality of the evidence, including sources of heterogeneity between study results.

Synthesis of Existing Research

Conclusions are more qualitative and may not be based on study quality.

Bases conclusion on quality of the studies and provide recommendations for practice or to address knowledge gaps.

Video: Reproducibility and transparent methods (Video 3:25)

Reporting standards

There are some reporting standards for evidence syntheses. These can serve as guidelines for protocol and manuscript preparation and journals may require that these standards are followed for the review type that is being employed (e.g. systematic review, scoping review, etc).​

  • PRISMA checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) is an evidence-based minimum set of items for reporting in systematic reviews and meta-analyses.
  • PRISMA-P Standards An updated version of the original PRISMA standards for protocol development.
  • PRISMA - ScR Reporting guidelines for scoping reviews and evidence maps
  • PRISMA-IPD Standards Extension of the original PRISMA standards for systematic reviews and meta-analyses of individual participant data.
  • EQUATOR Network The EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network is an international initiative that seeks to improve the reliability and value of published health research literature by promoting transparent and accurate reporting and wider use of robust reporting guidelines. They provide a list of various standards for reporting in systematic reviews.

Video: Guidelines and reporting standards

PRISMA flow diagram

The PRISMA flow diagram depicts the flow of information through the different phases of an evidence synthesis. It maps the search (number of records identified), screening (number of records included and excluded), and selection (reasons for exclusion). Many evidence syntheses include a PRISMA flow diagram in the published manuscript.

See below for resources to help you generate your own PRISMA flow diagram.

  • PRISMA Flow Diagram Tool
  • PRISMA Flow Diagram Word Template
  • << Previous: Schedule a Consultation / Meet our Team
  • Next: Types of Evidence Synthesis >>
  • Last Updated: Aug 1, 2024 10:30 AM
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Synthesising the literature as part of a literature review

Affiliation.

  • 1 University of Manchester, England.
  • PMID: 25783281
  • DOI: 10.7748/ns.29.29.44.e8957

This article examines how to synthesise and critique research literature. To place the process of synthesising the research literature into context, the article explores the critiquing process by breaking it down into seven sequential steps. The article explains how and why these steps need to be kept in mind if a robust comprehensive literature search and analysis are to be achieved. The article outlines how to engage in the critiquing process and explains how the literature review needs to be assembled to generate a logical and reasoned debate to examine a topic of interest or research in more detail.

Keywords: Critical analysis; critique; evaluation; integrative review; literature review; literature search; research; research question; search strategy; synthesis.

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  • Searching and critiquing the research literature. Wakefield A. Wakefield A. Nurs Stand. 2014 Jun 3;28(39):49-57. doi: 10.7748/ns.28.39.49.e8867. Nurs Stand. 2014. PMID: 24866671 Review.
  • How to perform a critically appraised topic: part 1, ask, search, and apply. Kelly AM, Cronin P. Kelly AM, et al. AJR Am J Roentgenol. 2011 Nov;197(5):1039-47. doi: 10.2214/AJR.09.7205. AJR Am J Roentgenol. 2011. PMID: 22021494
  • Reviewing Literature in Bioethics Research: Increasing Rigour in Non-Systematic Reviews. McDougall R. McDougall R. Bioethics. 2015 Sep;29(7):523-8. doi: 10.1111/bioe.12149. Epub 2015 Feb 6. Bioethics. 2015. PMID: 25655982
  • Critiquing research. Preston J. Preston J. Nurs Stand. 2015 Dec 2;30(14):61-2. doi: 10.7748/ns.30.14.61.s47. Nurs Stand. 2015. PMID: 26639295
  • Making sense of research: A guide for critiquing a paper. Stockhausen L, Conrick M. Stockhausen L, et al. Contemp Nurse. 2002 Dec;14(1):38-48. doi: 10.5172/conu.14.1.38. Contemp Nurse. 2002. PMID: 16114192 Review.
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Chapter 9: summarizing study characteristics and preparing for synthesis.

Joanne E McKenzie, Sue E Brennan, Rebecca E Ryan, Hilary J Thomson, Renea V Johnston

Key Points:

  • Synthesis is a process of bringing together data from a set of included studies with the aim of drawing conclusions about a body of evidence. This will include synthesis of study characteristics and, potentially, statistical synthesis of study findings.
  • A general framework for synthesis can be used to guide the process of planning the comparisons, preparing for synthesis, undertaking the synthesis, and interpreting and describing the results.
  • Tabulation of study characteristics aids the examination and comparison of PICO elements across studies, facilitates synthesis of these characteristics and grouping of studies for statistical synthesis.
  • Tabulation of extracted data from studies allows assessment of the number of studies contributing to a particular meta-analysis, and helps determine what other statistical synthesis methods might be used if meta-analysis is not possible.

Cite this chapter as: McKenzie JE, Brennan SE, Ryan RE, Thomson HJ, Johnston RV. Chapter 9: Summarizing study characteristics and preparing for synthesis. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. Available from www.training.cochrane.org/handbook .

9.1 Introduction

Synthesis is a process of bringing together data from a set of included studies with the aim of drawing conclusions about a body of evidence. Most Cochrane Reviews on the effects of interventions will include some type of statistical synthesis. Most commonly this is the statistical combination of results from two or more separate studies (henceforth referred to as meta-analysis) of effect estimates.

An examination of the included studies always precedes statistical synthesis in Cochrane Reviews. For example, examination of the interventions studied is often needed to itemize their content so as to determine which studies can be grouped in a single synthesis. More broadly, synthesis of the PICO (Population, Intervention, Comparator and Outcome) elements of the included studies underpins interpretation of review findings and is an important output of the review in its own right. This synthesis should encompass the characteristics of the interventions and comparators in included studies, the populations and settings in which the interventions were evaluated, the outcomes assessed, and the strengths and weaknesses of the body of evidence.

Chapter 2 defined three types of PICO criteria that may be helpful in understanding decisions that need to be made at different stages in the review:

  • The review PICO (planned at the protocol stage) is the PICO on which eligibility of studies is based (what will be included and what excluded from the review).
  • The PICO for each synthesis (also planned at the protocol stage) defines the question that the specific synthesis aims to answer, determining how the synthesis will be structured, specifying planned comparisons (including intervention and comparator groups, any grouping of outcome and population subgroups).
  • The PICO of the included studies (determined at the review stage) is what was actually investigated in the included studies.

In this chapter, we focus on the PICO for each synthesis and the PICO of the included studies , as the basis for determining which studies can be grouped for statistical synthesis and for synthesizing study characteristics. We describe the preliminary steps undertaken before performing the statistical synthesis. Methods for the statistical synthesis are described in Chapter 10 , Chapter 11 and Chapter 12 .

9.2 A general framework for synthesis

Box 9.2.a A general framework for synthesis that can be applied irrespective of the methods used to synthesize results

Set up the comparisons ( and ).

 

Summarize the characteristics of each study in a ‘Characteristics of included studies’ table (see ), including examining the interventions to itemize their content and other characteristics (Section ).

Determine which studies are similar enough to be grouped within each comparison by comparing the characteristics across studies (e.g. in a matrix) (Section ).

. Determine what data are available for synthesis (Section ; extraction of data and conversion to the desired format is discussed in and ).

Determine if modification to the planned comparisons or outcomes is necessary, or new comparisons are needed, noting any deviations from the protocol plans (Section ; and and ).

Synthesize the characteristics of the studies contributing to each comparison (Section ).

 

Perform a statistical synthesis (if appropriate), or provide structured reporting of the effects (Section 9.5; and , and ).

Interpret and describe the results, including consideration of the direction of effect, size of the effect, certainty of the evidence ( ), and the interventions tested and the populations in which they were tested.

Box 9.2.a provides a general framework for synthesis that can be applied irrespective of the methods used to synthesize results. Planning for the synthesis should start at protocol-writing stage, and Chapter 2 and Chapter 3 describe the steps involved in planning the review questions and comparisons between intervention groups. These steps included specifying which characteristics of the interventions, populations, outcomes and study design would be grouped together for synthesis (the PICO for each synthesis: stage 1 in Box 9.2.a ).

This chapter primarily concerns stage 2 of the general framework in Box 9.2.a . After deciding which studies will be included in the review and extracting data, review authors can start implementing their plan, working through steps 2.1 to 2.5 of the framework. This process begins with a detailed examination of the characteristics of each study (step 2.1), and then comparison of characteristics across studies in order to determine which studies are similar enough to be grouped for synthesis (step 2.2). Examination of the type of data available for synthesis follows (step 2.3). These three steps inform decisions about whether any modification to the planned comparisons or outcomes is necessary, or new comparisons are needed (step 2.4). The last step of the framework covered in this chapter involves synthesis of the characteristics of studies contributing to each comparison (step 2.5). The chapter concludes with practical tips for checking data before synthesis (Section 9.4 ).

Steps 2.1, 2.2 and 2.5 involve analysis and synthesis of mainly qualitative information about study characteristics. The process used to undertake these steps is rarely described in reviews, yet can require many subjective decisions about the nature and similarity of the PICO elements of the included studies. The examples described in this section illustrate approaches for making this process more transparent.

9.3 Preliminary steps of a synthesis

9.3.1 summarize the characteristics of each study (step 2.1).

A starting point for synthesis is to summarize the PICO characteristics of each study (i.e. the PICO of the included studies, see Chapter 3 ) and categorize these PICO elements in the groups (or domains) pre-specified in the protocol (i.e. the PICO for each synthesis). The resulting descriptions are reported in the ‘Characteristics of included studies’ table, and are used in step 2.2 to determine which studies can be grouped for synthesis.

In some reviews, the labels and terminology used in each study are retained when describing the PICO elements of the included studies. This may be sufficient in areas with consistent and widely understood terminology that matches the PICO for each synthesis. However, in most areas, terminology is variable, making it difficult to compare the PICO of each included study to the PICO for each synthesis, or to compare PICO elements across studies. Standardizing the description of PICO elements across studies facilitates these comparisons. This standardization includes applying the labels and terminology used to articulate the PICO for each synthesis ( Chapter 3 ), and structuring the description of PICO elements. The description of interventions can be structured using the Template for Intervention Description and Replication (TIDIeR) checklist, for example (see Chapter 3 and Table 9.3.a ).

Table 9.3.a illustrates the use of pre-specified groups to categorize and label interventions in a review of psychosocial interventions for smoking cessation in pregnancy (Chamberlain et al 2017). The main intervention strategy in each study was categorized into one of six groups: counselling, health education, feedback, incentive-based interventions, social support, and exercise. This categorization determined which studies were eligible for each comparison (e.g. counselling versus usual care; single or multi-component strategy). The extract from the ‘Characteristics of included studies’ table shows the diverse descriptions of interventions in three of the 54 studies for which the main intervention was categorized as ‘counselling’. Other intervention characteristics, such as duration and frequency, were coded in pre-specified categories to standardize description of the intervention intensity and facilitate meta-regression (not shown here).

Table 9.3.a Example of categorizing interventions into pre-defined groups

Definition of (selected) intervention groups from the PICO for each synthesis

: “provide[s] motivation to quit, support to increase problem solving and coping skills, and may incorporate ‘transtheoretical’ models of change. … includes … motivational interviewing, cognitive behaviour therapy, psychotherapy, relaxation, problem solving facilitation, and other strategies.”* : “ women receive a financial incentive, contingent on their smoking cessation; these incentives may be gift vouchers. … Interventions that provided a ‘chance’ of incentive (e.g. lottery tickets) combined with counselling were coded as counselling.” : “interventions where the intervention explicitly included provision of support from a peer (including self-nominated peers, ‘lay’ peers trained by project staff, or support from healthcare professionals), or from partners ” (Chamberlain et al 2017).

Study 1

Counselling

Incentive

Study 2

Routine prenatal advice on a range of health issues, from midwives and obstetricians plus:

Counselling

Social support

Study 3

Midwives received two and a half days of training on theory of transtheoretical model. Participants received a set of six stage-based self-help manuals ‘Pro-Change programme for a healthy pregnancy’. The midwife assessed each participant’s stage of change and pointed the woman to the appropriate manual. No more than 15 minutes was spent on the intervention.

Counselling

Nil

* The definition also specified eligible modes of delivery, intervention duration and personnel.

While this example focuses on categorizing and describing interventions according to groups pre-specified in the PICO for each synthesis, the same approach applies to other PICO elements.

9.3.2 Determine which studies are similar enough to be grouped within each comparison (step 2.2)

Once the PICO of included studies have been coded using labels and descriptions specified in the PICO for each synthesis, it will be possible to compare PICO elements across studies and determine which studies are similar enough to be grouped within each comparison.

Tabulating study characteristics can help to explore and compare PICO elements across studies, and is particularly important for reviews that are broad in scope, have diversity across one or more PICO elements, or include large numbers of studies. Data about study characteristics can be ordered in many different ways (e.g. by comparison or by specific PICO elements), and tables may include information about one or more PICO elements. Deciding on the best approach will depend on the purpose of the table and the stage of the review. A close examination of study characteristics will require detailed tables; for example, to identify differences in characteristics that were pre-specified as potentially important modifiers of the intervention effects. As the review progresses, this detail may be replaced by standardized description of PICO characteristics (e.g. the coding of counselling interventions presented in Table 9.3.a ).

Table 9.3.b illustrates one approach to tabulating study characteristics to enable comparison and analysis across studies. This table presents a high-level summary of the characteristics that are most important for determining which comparisons can be made. The table was adapted from tables presented in a review of self-management education programmes for osteoarthritis (Kroon et al 2014). The authors presented a structured summary of intervention and comparator groups for each study, and then categorized intervention components thought to be important for enabling patients to manage their own condition. Table 9.3.b shows selected intervention components, the comparator, and outcomes measured in a subset of studies (some details are fictitious). Outcomes have been grouped by the outcome domains ‘Pain’ and ‘Function’ (column ‘Outcome measure’ Table 9.3.b ). These pre-specified outcome domains are the chosen level for the synthesis as specified in the PICO for each synthesis. Authors will need to assess whether the measurement methods or tools used within each study provide an appropriate assessment of the domains ( Chapter 3, Section 3.2.4 ). A next step is to group each measure into the pre-specified time points. In this example, outcomes are grouped into short-term (<6 weeks) and long-term follow-up (≥6 weeks to 12 months) (column ‘Time points (time frame)’ Table 9.3.b ).

Variations on the format shown in Table 9.3.b can be presented within a review to summarize the characteristics of studies contributing to each synthesis, which is important for interpreting findings (step 2.5).

Table 9.3.b Table of study characteristics illustrating similarity of PICO elements across studies

1

Attention control

BEH

   

MON

CON

SKL

NAV

Pain

Pain VAS

1 mth (short), 8 mths (long)

Mean, N / group

Yes

Function

HAQ disability subscale

1 mth (short), 8 mths (long)

Median, IQR, N / group

Maybe

2

Acupuncture

BEH

 

EMO

 

CON

SKL

NAV

Pain

Pain on walking VAS

1 mth (short), 12 mths (long)

MD from ANCOVA model, 95%CI

Yes

Function

Dutch AIMS-SF

1 mth (short), 12 mths (long)

Median, range, N / group

Maybe

4

Information

BEH

ENG

EMO

MON

CON

SKL

NAV

Pain

Pain VAS

1 mth (short)

MD, SE

Yes

Function

Dutch AIMS-SF

1 mth (short)

Mean, SD, N / group

Yes

12

Information

BEH

       

SKL

 

Pain

WOMAC pain subscore

12 mths (long)

MD from ANCOVA model, 95%CI

Yes

3

Usual care

BEH

 

EMO

MON

 

SKL

NAV

Pain

Pain VAS*

Pain on walking VAS

1 mth (short)

1 mth (short)

Mean, SD, N / group

Yes

5

Usual care

BEH

ENG

EMO

MON

CON

SKL

 

Pain

Pain on walking VAS

2 wks (short)

Mean, SD, N / group

Yes

6

Usual care

BEH

   

MON

CON

SKL

NAV

Pain

Pain VAS

2 wks (short), 1 mth (short)*

MD, t-value and P value for MD

Yes

Function

WOMAC disability subscore

2 wks (short), 1 mth (short)*

Mean, N / group

Yes

7

Usual care

BEH

   

MON

CON

SKL

NAV

Pain

WOMAC pain subscore

1 mth (short)

Direction of effect

No

Function

WOMAC disability subscore

1 mth (short)

Means, N / group; statistically significant difference

Yes

8

Usual care

     

MON

     

Pain

Pain VAS

12 mths (long)

MD, 95%CI

Yes

9

Usual care

BEH

   

MON

 

SKL

 

Function

Global disability

12 mths (long)

Direction of effect, NS

No

10

Usual care

BEH

 

EMO

MON

CON

SKL

NAV

Pain

Pain VAS

1 mth (short)

No information

No

Function

Global disability

1 mth (short)

Direction of effect

No

11

Usual care

BEH

   

MON

 

SKL

 

Pain

WOMAC pain subscore

1 mth (short), 12 mths (long)

Mean, SD, N / group

Yes

BEH = health-directed behaviour; CON = constructive attitudes and approaches; EMO = emotional well-being; ENG = positive and active engagement in life; MON = self-monitoring and insight; NAV = health service navigation; SKL = skill and technique acquisition. ANCOVA = Analysis of covariance; CI = confidence interval; IQR = interquartile range; MD = mean difference; SD = standard deviation; SE = standard error, NS = non-significant. Pain and function measures: Dutch AIMS-SF = Dutch short form of the Arthritis Impact Measurement Scales; HAQ = Health Assessment Questionnaire; VAS = visual analogue scale; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index. 1 Ordered by type of comparator; 2 Short-term (denoted ‘immediate’ in the review Kroon et al (2014)) follow-up is defined as <6 weeks, long-term follow-up (denoted ‘intermediate’ in the review) is ≥6 weeks to 12 months; 3 For simplicity, in this example the available data are assumed to be the same for all outcomes within an outcome domain within a study. In practice, this is unlikely and the available data would likely vary by outcome; 4 Indicates that an effect estimate and its standard error may be computed through imputation of missing statistics, methods to convert between statistics (e.g. medians to means) or contact with study authors. *Indicates the selected outcome when there was multiplicity in the outcome domain and time frame.

9.3.3 Determine what data are available for synthesis (step 2.3)

Once the studies that are similar enough to be grouped together within each comparison have been determined, a next step is to examine what data are available for synthesis. Tabulating the measurement tools and time frames as shown in Table 9.3.b allows assessment of the potential for multiplicity (i.e. when multiple outcomes within a study and outcome domain are available for inclusion ( Chapter 3, Section 3.2.4.3 )). In this example, multiplicity arises in two ways. First, from multiple measurement instruments used to measure the same outcome domain within the same time frame (e.g. ‘Short-term Pain’ is measured using the ‘Pain VAS’ and ‘Pain on walking VAS’ scales in study 3). Second, from multiple time points measured within the same time frame (e.g. ‘Short-term Pain’ is measured using ‘Pain VAS’ at both 2 weeks and 1 month in study 6). Pre-specified methods to deal with the multiplicity can then be implemented (see Table 9.3.c for examples of approaches for dealing with multiplicity). In this review, the authors pre-specified a set of decision rules for selecting specific outcomes within the outcome domains. For example, for the outcome domain ‘Pain’, the selected outcome was the highest on the following list: global pain, pain on walking, WOMAC pain subscore, composite pain scores other than WOMAC, pain on activities other than walking, rest pain or pain during the night. The authors further specified that if there were multiple time points at which the outcome was measured within a time frame, they would select the longest time point. The selected outcomes from applying these rules to studies 3 and 6 are indicated by an asterisk in Table 9.3.b .

Table 9.3.b also illustrates an approach to tabulating the extracted data. The available statistics are tabulated in the column labelled ‘Data’, from which an assessment can be made as to whether the study contributes the required data for a meta-analysis (column ‘Effect & SE’) ( Chapter 10 ). For example, of the seven studies comparing health-directed behaviour (BEH) with usual care, six measured ‘Short-term Pain’, four of which contribute required data for meta-analysis. Reordering the table by comparison, outcome and time frame, will more readily show the number of studies that will contribute to a particular meta-analysis, and help determine what other synthesis methods might be used if the data available for meta-analysis are limited.

Table 9.3.c Examples of approaches for selecting one outcome (effect estimate) for inclusion in a synthesis.* Adapted from López-López et al (2018)

Random selection

Randomly select an outcome (effect estimate) when multiple are available for an outcome domain

Assumes that the effect estimates are interchangeable measures of the domain and that random selection will yield a ‘representative’ effect for the meta-analysis.

Averaging of effect estimates

Calculate the average of the intervention effects when multiple are available for a particular outcome domain

Assumes that the effect estimates are interchangeable measures of the domain. The standard error of the average effect can be calculated using a simple method of averaging the variances of the effect estimates.

Median effect estimate

Rank the effect estimates of outcomes within an outcome domain and select the outcome with the middle value

An alternative to averaging effect estimates. Assumes that the effect estimates are interchangeable measures of the domain and that the median effect will yield a ‘representative’ effect for the meta-analysis. This approach is often adopted in Effective Practice and Organization of Care reviews that include broad outcome domains.

Decision rules

Select the most relevant outcome from multiple that are available for an outcome domain using a decision rule

Assumes that while the outcomes all provide a measure of the outcome domain, they are not completely interchangeable, with some being more relevant. The decision rules aim to select the most relevant. The rules may be based on clinical (e.g. content validity of measurement tools) or methodological (e.g. reliability of the measure) considerations. If multiple rules are specified, a hierarchy will need to be determined to specify the order in which they are applied.

9.3.4 Determine if modification to the planned comparisons or outcomes is necessary, or new comparisons are needed (step 2.4)

The previous steps may reveal the need to modify the planned comparisons. Important variations in the intervention may be identified leading to different or modified intervention groups. Few studies or sparse data, or both, may lead to different groupings of interventions, populations or outcomes. Planning contingencies for anticipated scenarios is likely to lead to less post-hoc decision making ( Chapter 2 and Chapter 3 ); however, it is difficult to plan for all scenarios. In the latter circumstance, the rationale for any post-hoc changes should be reported. This approach was adopted in a review examining the effects of portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco (Hollands et al 2015). After preliminary examination of the outcome data, the review authors changed their planned intervention groups. They judged that intervention groups based on ‘size’ and those based on ‘shape’ of the products were not conceptually comparable, and therefore should form separate comparisons. The authors provided a rationale for the change and noted that it was a post-hoc decision.

9.3.5 Synthesize the characteristics of the studies contributing to each comparison (step 2.5)

A final step, and one that is essential for interpreting combined effects, is to synthesize the characteristics of studies contributing to each comparison. This description should integrate information about key PICO characteristics across studies, and identify any potentially important differences in characteristics that were pre-specified as possible effect modifiers. The synthesis of study characteristics is also needed for GRADE assessments, informing judgements about whether the evidence applies directly to the review question (indirectness) and analyses conducted to examine possible explanations for heterogeneity (inconsistency) (see Chapter 14 ).

Tabulating study characteristics is generally preferable to lengthy description in the text, since the structure imposed by a table can make it easier and faster for readers to scan and identify patterns in the information presented. Table 9.3.b illustrates one such approach. Tabulating characteristics of studies that contribute to each comparison can also help to improve the transparency of decisions made around grouping of studies, while also ensuring that studies that do not contribute to the combined effect are accounted for.

9.4 Checking data before synthesis

Before embarking on a synthesis, it is important to be confident that the findings from the individual studies have been collated correctly. Therefore, review authors must compare the magnitude and direction of effects reported by studies with how they are to be presented in the review. This is a reasonably straightforward way for authors to check a number of potential problems, including typographical errors in studies’ reports, accuracy of data collection and manipulation, and data entry into RevMan. For example, the direction of a standardized mean difference may accidentally be wrong in the review. A basic check is to ensure the same qualitative findings (e.g. direction of effect and statistical significance) between the data as presented in the review and the data as available from the original study.

Results in forest plots should agree with data in the original report (point estimate and confidence interval) if the same effect measure and statistical model is used. There are legitimate reasons for differences, however, including: using a different measure of intervention effect; making different choices between change-from-baseline measures, post-intervention measures alone or post-intervention measures adjusted for baseline values; grouping similar intervention groups; or making adjustments for unit-of-analysis errors in the reports of the primary studies.

9.5 Types of synthesis

The focus of this chapter has been describing the steps involved in implementing the planned comparisons between intervention groups (stage 2 of the general framework for synthesis ( Box 9.2.a )). The next step (stage 3) is often performing a statistical synthesis. Meta-analysis of effect estimates, and its extensions have many advantages. There are circumstances under which a meta-analysis is not possible, however, and other statistical synthesis methods might be considered, so as to make best use of the available data. Available summary and synthesis methods, along with the questions they address and examples of associated plots, are described in Table 9.5.a . Chapter 10 and Chapter 11 discuss meta-analysis (of effect estimate) methods, while Chapter 12 focuses on the other statistical synthesis methods, along with approaches to tabulating, visually displaying and providing a structured presentation of the findings. An important part of planning the analysis strategy is building in contingencies to use alternative methods when the desired method cannot be used.

Table 9.5.a Overview of available methods for summary and synthesis

 

Text/Tabular

Vote counting

Combining P values

Summary of effect estimates

Pairwise meta-analysis

Network meta-analysis

Subgroup analysis/meta-regression

Narrative summary of evidence presented in either text or tabular form

Is there any evidence of an effect?

Is there evidence that there is an effect in at least one study?

What is the range and distribution of observed effects?

What is the common intervention effect? (fixed-effect model)

What is the average intervention effect? (random effects model)

Which intervention of multiple is most effective?

What factors modify the magnitude of the intervention effects?

Forest plot (plotting individual study effects without a combined effect estimate)

Harvest plot

Effect direction plot

Albatross plot

Box and whisker plot

Bubble plot

Forest plot

Forest plot

Network diagram

Rankogram plots

Forest plot

Box and whisker plot

Bubble plot

9.6 Chapter information

Authors: Joanne E McKenzie, Sue E Brennan, Rebecca E Ryan, Hilary J Thomson, Renea V Johnston

Acknowledgements: Sections of this chapter build on Chapter 9 of version 5.1 of the Handbook , with editors Jonathan Deeks, Julian Higgins and Douglas Altman. We are grateful to Julian Higgins, James Thomas and Tianjing Li for commenting helpfully on earlier drafts.

Funding: JM is supported by an NHMRC Career Development Fellowship (1143429). SB and RR’s positions are supported by the NHMRC Cochrane Collaboration Funding Program. HT is funded by the UK Medical Research Council (MC_UU_12017-13 and MC_UU_12017-15) and Scottish Government Chief Scientist Office (SPHSU13 and SPHSU15). RJ’s position is supported by the NHMRC Cochrane Collaboration Funding Program and Cabrini Institute.

9.7 References

Chamberlain C, O’Mara-Eves A, Porter J, Coleman T, Perlen SM, Thomas J, McKenzie JE. Psychosocial interventions for supporting women to stop smoking in pregnancy. Cochrane Database of Systematic Reviews 2017; 2 : CD001055.

Hollands GJ, Shemilt I, Marteau TM, Jebb SA, Lewis HB, Wei Y, Higgins JPT, Ogilvie D. Portion, package or tableware size for changing selection and consumption of food, alcohol and tobacco. Cochrane Database of Systematic Reviews 2015; 9 : CD011045.

Kroon FPB, van der Burg LRA, Buchbinder R, Osborne RH, Johnston RV, Pitt V. Self-management education programmes for osteoarthritis. Cochrane Database of Systematic Reviews 2014; 1 : CD008963.

López-López JA, Page MJ, Lipsey MW, Higgins JPT. Dealing with effect size multiplicity in systematic reviews and meta-analyses. Research Synthesis Methods 2018; 9 : 336–351.

For permission to re-use material from the Handbook (either academic or commercial), please see here for full details.

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  • Conducting a Literature Review by Ann Dyer Last Updated Aug 13, 2024 1978 views this year

Doing Diligence

The first step in any systematic review or other type of evidence synthesis project is to search the existing literature to identify what research, both primary and secondary, has already been conducted. As with any publication, your review will likely need to be original/novel in order to be of interest to editors and publications. In addition, duplicating a previously done study may not add new understandings to the body of evidence. Here are some questions for consideration:

  • Has your research question already been answered?
  • How recently has the existing secondary research been conducted/published?
  • Does the existing secondary research need to be updated due to new original research that has been conducted after its publication?
  • Is there existing secondary research that answers a different research question than the one you want to answer?
  • How does your question, methodology, or timing differ from existing research?

All of these questions will help you identify  why  you would conduct this new study. It is disheartening (at best) to learn part way through an evidence synthesis project that the research has already been conducted.

Search Published Literature

Search for published studies that address your research question. This should be done in several different databases to ensure you have a solid sense of what has already been accomplished. It will also inform the way that you create your search strategy for this study, as you'll learn the types of words that are used to describe this research question, publications that have published these types of studies, and how the articles have been indexed within the databases. Below are a few databases that you might consider searching for health sciences publications.

  • PubMed This link to PubMed is for those affiliated with WSU. PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
  • EMBASE Embase is an abstract and Indexing (A & I) database covering over 8,500 journal titles, 30 million articles back to 1974, all disciplines of medicine and biomedical science, and includes substantial coverage of Allied Health subjects.
  • CINAHL Complete (EBSCOHost) CINAHL Complete is the world's most comprehensive source of full-text for nursing & allied health journals, providing full text for more than 1,300 journals indexed in CINAHL.
  • APA PsycInfo (ProQuest) This link opens in a new window An index with summaries of citations to articles in over 1,300 psychology research journals. Articles date from 1806 - present. Note: There are less than 146 records with publication dates prior to 1890. Updated weekly.

Search for Preregistrations

In addition to finding articles that have already been published, you will need to search registries to see if others are currently in the process of researching this topic/question, just as you would for clinical research. Here are a few repositories for you to search:

  • Open Science Framework (OSF) Registries
  • Cochrane Preregistrations
  • Campbell Preregistrations

Identification of Review Type

While considering conducting a literature review, you should compare your draft research question to the different review types that can be used to explore the existing research. Some types, such as narrative reviews, do not consider the literature search as a formal methodology, while others such as Systematic Reviews view the literature search as a reproducible research methodology.

As a first step, search the literature for other published articles and studies that address the same or similar research question. The quantity, quality, and depth of existing research will be an important component in deciding on a review type.

Selection of the review type includes not only aspirations for what the review could accomplish, but also pragmatic limitations based on how much time the team has to devote to the project, how many team members are participating in the review, and deadlines for the review completion (such as the date of an upcoming conference). In addition, the breadth of the research question may result in a large number of search results; this should be considered in terms of the number of team members involved in the screening and abstraction of the included studies, as well as whether the research question should be narrowed or include more limitations/exclusion criteria in order to satisfy the practical limitations of the team.

Use the decision tree below from Cornell University to determine what type of review best suits your question/topic and available resources. The PDF is linked for you to view/download along with descriptions of the review types, with an image of the decision tree displayed on this page. To learn more about the different types, purposes, and methods of reviews, click the "Types of Reviews" link below the decision tree. 

Types of Reviews

  • What Type of Review is Right For You? | Decision Tree

what is a synthesis of the literature

Reproduced from Grant, M. J. and Booth, A. (2009), A typology of reviews: an analysis of 14 review types and associated methodologies. Health Information & Libraries Journal, 26: 91–108. doi: 10.1111/j.1471-1842.2009.00848.x 

Label Description Search Appraisal Synthesis Analysis
Critical Review Aims to demonstrate writer has extensively researched literature and critically evaluated its quality. Goes beyond mere description to include degree of analysis and conceptual innovation. Typically results in hypothesis or model Seeks to identify most significant items in the field No formal quality assessment. Attempts to evaluate according to contribution Typically narrative, perhaps conceptual or chronological Significant component: seeks to identify conceptual contribution to embody existing or derive new theory
Literature Review Generic term: published materials that provide examination of recent or current literature. Can cover wide range of subjects at various levels of completeness and comprehensiveness. May include research findings May or may not include comprehensive searching May or may not include quality assessment Typically narrative Analysis may be chronological, conceptual, thematic, etc.
Mapping Review / Systematic Map Map out and categorize existing literature from which to commission further reviews and/or primary research by identifying gaps in research literature Completeness of searching determined by time/scope constraints No formal quality assessment May be graphical and tabular Characterizes quantity and quality of literature, perhaps by study design and other key features. May identify need for primary or secondary research
Meta-Analysis Technique that statistically combines the results of quantitative studies to provide a more precise effect of the results Aims for exhaustive, comprehensive searching. May use funnel plot to assess completeness Quality assessment may determine inclusion/exclusion and/or sensitivity analyses Graphical and tabular with narrative commentary Numerical analysis of measures of effect assuming absence of heterogeneity
Mixed Studies Review / Mixed Methods Review Refers to any combination of methods where one significant component is a literature review (usually systematic). Within a review context it refers to a combination of review approaches for example combining quantitative with qualitative research or outcome with process studies Requires either very sensitive search to retrieve all studies or separately conceived quantitative and qualitative strategies Requires either a generic appraisal instrument or separate appraisal processes with corresponding checklists Typically both components will be presented as narrative and in tables. May also employ graphical means of integrating quantitative and qualitative studies Analysis may characterise both literatures and look for correlations between characteristics or use gap analysis to identify aspects absent in one literature but missing in the other
Overview Generic term: summary of the [medical] literature that attempts to survey the literature and describe its characteristics May or may not include comprehensive searching (depends whether systematic overview or not) May or may not include quality assessment (depends whether systematic overview or not) Synthesis depends on whether systematic or not. Typically narrative but may include tabular features Analysis may be chronological, conceptual, thematic, etc.
Qualitative Systematic Review / Qualitative Evidence Synthesis Method for integrating or comparing the findings from qualitative studies. It looks for ‘themes’ or ‘constructs’ that lie in or across individual qualitative studies May employ selective or purposive sampling Quality assessment typically used to mediate messages not for inclusion/exclusion Qualitative, narrative synthesis Thematic analysis, may include conceptual models
Rapid Review Assessment of what is already known about a policy or practice issue, by using systematic review methods to search and critically appraise existing research Completeness of searching determined by time constraints Time-limited formal quality assessment Typically narrative and tabular Quantities of literature and overall quality/direction of effect of literature
Scoping Review Preliminary assessment of potential size and scope of available research literature. Aims to identify nature and extent of research evidence (usually including ongoing research) Completeness of searching determined by time/scope constraints. May include research in progress No formal quality assessment Typically tabular with some narrative commentary Characterizes quantity and quality of literature, perhaps by study design and other key features. Attempts to specify a viable review
State-of-the-Art Review Tend to address more current matters in contrast to other combined retrospective and current approaches. May offer new perspectives on issue or point out area for further research Aims for comprehensive searching of current literature Aims for comprehensive searching of current literature Typically narrative, may have tabular accompaniment Current state of knowledge and priorities for future investigation and research
Systematic Review Seeks to systematically search for, appraise and synthesis research evidence, often adhering to guidelines on the conduct of a review Aims for exhaustive, comprehensive searching Quality assessment may determine inclusion/exclusion Typically narrative with tabular accompaniment What is known; recommendations for practice. What remains unknown; uncertainty around findings, recommendations for future research
Systematic Search and Review Combines strengths of critical review with a comprehensive search process. Typically addresses broad questions to produce ‘best evidence synthesis’ Aims for exhaustive, comprehensive searching May or may not include quality assessment Minimal narrative, tabular summary of studies What is known; recommendations for practice. Limitations
Systematized Review Attempt to include elements of systematic review process while stopping short of systematic review. Typically conducted as postgraduate student assignment May or may not include comprehensive searching May or may not include quality assessment Typically narrative with tabular accompaniment What is known; uncertainty around findings; limitations of methodology
Umbrella Review Specifically refers to review compiling evidence from multiple reviews into one accessible and usable document. Focuses on broad condition or problem for which there are competing interventions and highlights reviews that address these interventions and their results Identification of component reviews, but no search for primary studies Quality assessment of studies within component reviews and/or of reviews themselves Graphical and tabular with narrative commentary What is known; recommendations for practice. What remains unknown; recommendations for future research

Develop a Searchable Question

When developing a searchable question, it helps to identify the key concepts of your research proposal. A clear and precise search question can be used to develop search terms during the literature searching process.

There are a number of frameworks available to use to help you break your question into its key concepts. Take a look at the frameworks below. 

  • Evidence-Based Practice
  • General Health
  • Health Management

From BMJ Best Practice :

The PICO (Population, Intervention, Comparator and Outcomes) model captures the key elements and is a good strategy to provide answerable questions.

Population : who are the relevant patients or the target audience for the problem being addressed?      Example: In women with non-tubal infertility

Intervention : what intervention is being considered?     Example: …would intrauterine insemination…

Comparator : what is the main comparator to the intervention that you want to assess?      Example: …when compared with fallopian tube sperm perfusion…

Outcomes : what are the consequences of the interventions for the patient? Or what are the main outcomes of interest to the patient or decision maker?      Example: …lead to higher live birth rates with no increase in multiple pregnancy, miscarriage or ectopic pregnancy rates?

How to clarify a clinical question. (n.d.). BMJ Best Practice . Retrieved October 26, 2022, from https://bestpractice.bmj.com/info/us/toolkit/learn-ebm/how-to-clarify-a-clinical-question/

From "Formulating the Evidence Based Practice Question":

Setting : What is the context for the question? The research evidence should reflect the context or the research findings may not be transferable.

Perspective : Who are the users, potential users, or stakeholders of the service?

Intervention : What is being done for the users, potential users, or stakeholders?

Comparison : What are the alternatives? An alternative might maintain the status quo and change nothing.

Evaluation : What measurement will determine the intervention’s success? In other words, what is the result?

Davies, K. S. (2011). Formulating the Evidence Based Practice Question: A Review of the Frameworks. Evidence Based Library and Information Practice , 6 (2), Article 2. https://doi.org/10.18438/B8WS5N

From "How CLIP became ECLIPSE":

Expectation —what does the search requester want the information for (the original ‘I’s)? Client Group Location Impact:  what is the change in the service, if any, which is being looked for? What would constitute success? How is this being measured? Professionals Service:  for which service are you looking for information? For example, outpatient services, nurse-led clinics, intermediate care

Wildridge, V., & Bell, L. (2002). How CLIP became ECLIPSE: A mnemonic to assist in searching for health policy/management information. Health Information & Libraries Journal , 19 (2), 113–115. https://doi.org/10.1046/j.1471-1842.2002.00378.x

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  1. 6. Synthesize

    In the four examples below, only ONE shows a good example of synthesis: the fourth column, or Student D. For a web accessible version, click the link below the image. For a web accessible version, click the link below the image.

  2. Literature Synthesis 101: How To Guide + Examples

    Simply put, literature synthesis means going beyond just describing what everyone has said and found. Instead, synthesis is about bringing together all the information from various sources to present a cohesive assessment of the current state of knowledge in relation to your study's research aims and questions.

  3. How To Write Synthesis In Research: Example Steps

    Step 1 Organize your sources. Step 2 Outline your structure. Step 3 Write paragraphs with topic sentences. Step 4 Revise, edit and proofread. When you write a literature review or essay, you have to go beyond just summarizing the articles you've read - you need to synthesize the literature to show how it all fits together (and how your own ...

  4. Synthesize

    Synthesis Matrix. A synthesis matrix helps you record the main points of each source and document how sources relate to each other. After summarizing and evaluating your sources, arrange them in a matrix or use a citation manager to help you see how they relate to each other and apply to each of your themes or variables. By arranging your ...

  5. Synthesis

    Synthesis is a complex activity, which requires a high degree of comprehension and active engagement with the subject. As you progress in higher education, so increase the expectations on your abilities to synthesise. How to synthesise in a literature review: Identify themes/issues you'd like to discuss in the literature review. Think of an ...

  6. Synthesizing Research

    Synthesis, step by step. This is what you need to do before you write your review. Identify and clearly describe your research question ... Your literature review will collect the results of this analysis and explain them in relation to your research question. Analysis tips

  7. PDF Writing A Literature Review and Using a Synthesis Matrix

    One way that seems particularly helpful in organizing literature reviews is the synthesis matrix. The synthesis matrix is a chart that allows a researcher to sort and categorize the different arguments presented on an issue. Across the top of the chart are the spaces to record sources, and along the side of the chart are the spaces to record ...

  8. LibGuides: Literature Review How To: Synthesizing Sources

    Literature reviews synthesize large amounts of information and present it in a coherent, organized fashion. In a literature review you will be combining material from several texts to create a new text - your literature review. You will use common points among the sources you have gathered to help you synthesize the material.

  9. LibGuides: Literature Reviews: 5. Synthesize your findings

    How to synthesize. In the synthesis step of a literature review, researchers analyze and integrate information from selected sources to identify patterns and themes. This involves critically evaluating findings, recognizing commonalities, and constructing a cohesive narrative that contributes to the understanding of the research topic. Synthesis.

  10. Literature Synthesis

    As posed by Pawson et al. ( 2005 ), it consists of a technique composed of five steps: (1) explain the scope; (2) search for evidence; (3) evaluate primary studies and extract data; (4) synthesize evidence and conclude; and (5) disseminate, implement and evaluate. In the first step, the review question is defined.

  11. LibGuides: Literature Review Step by Step: Synthesize

    Forming a synthesis between various ideas is the heart of your literature review, and once done, will be the core of your research paper. As a starting point try: • finding ideas that are common or controversial. • two or three important trends in the research. • the most influential theories. As you read keep these questions in mind:

  12. Synthesizing Sources

    Synthesis matrix. To more easily determine the similarities and dissimilarities among your sources, you can create a visual representation of their main ideas with a synthesis matrix. This is a tool that you can use when researching and writing your paper, not a part of the final text.

  13. Step 2: Analysis, synthesis, critique

    Skill #3: Critique. As you are writing your literature review, you will want to apply a critical eye to the literature you have evaluated and synthesized. Consider the strong arguments you will make contrasted with the potential gaps in previous research. The words that you choose to report your critiques of the literature will be non-neutral.

  14. Conducting a Literature Review: Synthesize

    Review the information in the Resources box to learn about using a synthesis matrix. Create your own literature review synthesis matrix using the Word or Excel files available in the Activity box. Organize and synthesize literature related to your topic using your synthesis matrix;

  15. Step 5: Synthesize

    Synthesis refers to combining separate elements to create a whole. When reading through your sources (peer reviewed journal articles, books, research studies, white papers etc.) you will pay attention to relationships between the studies, between groups in the studies, and look for any pattterns, similarities or differences.

  16. What is a Literature Review? How to Write It (with Examples)

    A literature review is a critical analysis and synthesis of existing research on a particular topic. It provides an overview of the current state of knowledge, identifies gaps, and highlights key findings in the literature. 1 The purpose of a literature review is to situate your own research within the context of existing scholarship ...

  17. Synthetic literature reviews: An introduction

    Rather than explaining and reflecting on the results of previous studies (as is typically done in literature reviews), a synthetic literature review strives to create a new and more useful theoretical perspective by rigorously integrating the results of previous studies. Many people find the process of synthesis difficult, elusive, or ...

  18. Literature Synthesis 101: How to Synthesise In Your ...

    Learn how to synthesise the existing literature for your literature review by addressing five key questions. In this video, we explain exactly how you can en...

  19. How to Synthesise Sources

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  20. A Guide to Evidence Synthesis: What is Evidence Synthesis?

    They generally include a methodical and comprehensive literature synthesis focused on a well-formulated research question. Their aim is to identify and synthesize all of the scholarly research on a particular topic, including both published and unpublished studies. Evidence syntheses are conducted in an unbiased, reproducible way to provide ...

  21. Systematic Reviews & Evidence Synthesis Methods

    They generally include a methodical and comprehensive literature synthesis focused on a well-formulated research question. Their aim is to identify and synthesize all of the scholarly research on a particular topic, including both published and unpublished studies. Evidence syntheses are conducted in an unbiased, reproducible way to provide ...

  22. Synthesising the literature as part of a literature review

    Review Literature as Topic*. This article examines how to synthesise and critique research literature. To place the process of synthesising the research literature into context, the article explores the critiquing process by breaking it down into seven sequential steps. The article explains how and why these steps need to be ke ….

  23. PDF 1. Planning a Synthesis Paper

    Literature Review: Synthesizing Multiple Sources The term "synthesis" means to combine separate elements to form a whole. Writing teachers often use this term when they assign students to write a literature review or other paper that requires the use of a variety of sources. When writing teachers use this term, they often hope that students ...

  24. Synthesis for Literature Reviews

    This video gives you tips on conducting literature reviews using synthesis methods.Creative Commons License:This work is licensed under a Creative Commons At...

  25. Chapter 9: Summarizing study characteristics and preparing for synthesis

    Box 9.2.a provides a general framework for synthesis that can be applied irrespective of the methods used to synthesize results. Planning for the synthesis should start at protocol-writing stage, and Chapter 2 and Chapter 3 describe the steps involved in planning the review questions and comparisons between intervention groups. These steps included specifying which characteristics of the ...

  26. LibGuides: Evidence Synthesis Service: Starting a Review

    The first step in any systematic review or other type of evidence synthesis project is to search the existing literature to identify what research, both primary and secondary, has already been conducted. As with any publication, your review will likely need to be original/novel in order to be of interest to editors and publications.

  27. (PDF) The Essentials of Conducting a Literature Review: A Guide to

    The literature review is a fundamental component of academic work, serving to synthesize existing knowledge, critique methodologies, and potentially generate new insights through reconceptualization.